Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.N.S., J.-X.L.); Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia (S.O., Yan.Z.); and Research Triangle Institute, Research Triangle Park, North Carolina (Yanan.Z.)

Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.N.S., J.-X.L.); Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia (S.O., Yan.Z.); and Research Triangle Institute, Research Triangle Park, North Carolina (Yanan.Z.)

Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.N.S., J.-X.L.); Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia (S.O., Yan.Z.); and Research Triangle Institute, Research Triangle Park, North Carolina (Yanan.Z.)

Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.N.S., J.-X.L.); Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia (S.O., Yan.Z.); and Research Triangle Institute, Research Triangle Park, North Carolina (Yanan.Z.)

Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.N.S., J.-X.L.); Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia (S.O., Yan.Z.); and Research Triangle Institute, Research Triangle Park, North Carolina (Yanan.Z.)