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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

June 01, 2016; Volume 357,Issue 3

Minireview

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    Dopamine Reuptake Inhibitors in Parkinson’s Disease: A Review of Nonhuman Primate Studies and Clinical Trials
    Philippe Huot, Susan H. Fox and Jonathan M. Brotchie
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 562-569; DOI: https://doi.org/10.1124/jpet.116.232371

Behavioral Pharmacology

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    Antinociceptive Interactions between the Imidazoline I2 Receptor Agonist 2-BFI and Opioids in Rats: Role of Efficacy at the μ-Opioid Receptor
    Justin N. Siemian, Samuel Obeng, Yan Zhang, Yanan Zhang and Jun-Xu Li
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 509-519; DOI: https://doi.org/10.1124/jpet.116.232421
  • Open Access
    Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives
    S. Khom, J. Hintersteiner, D. Luger, M. Haider, G. Pototschnig, M. D. Mihovilovic, C. Schwarzer and S. Hering
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 580-590; DOI: https://doi.org/10.1124/jpet.116.232983

Cardiovascular

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    C-Type Natriuretic Peptide Improves Left Ventricular Functional Performance at Rest and Restores Normal Exercise Responses after Heart Failure
    Tiankai Li, Heng-Jie Cheng, Nobuyuki Ohte, Hiroshi Hasegawa, Atsushi Morimoto, David M. Herrington, William C. Little, Weimin Li and Che Ping Cheng
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 545-553; DOI: https://doi.org/10.1124/jpet.115.231696

Drug Discovery and Translational Medicine

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    β-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1– and Oxidative Stress–Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis
    Yougen Wu, Xue Wang, Siyu Chang, Weiqiang Lu, Mingyao Liu and Xiufeng Pang
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 466-475; DOI: https://doi.org/10.1124/jpet.116.232694
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    Enolate-Forming Phloretin Pharmacophores: Hepatoprotection in an Experimental Model of Drug-Induced Toxicity
    Brian C. Geohagen, Amaresh Vydyanathan, Boleslav Kosharskyy, Naum Shaparin, Terrence Gavin and Richard M. LoPachin
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 476-486; DOI: https://doi.org/10.1124/jpet.115.231001
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    TASP0434299: A Novel Pyridopyrimidin-4-One Derivative as a Radioligand for Vasopressin V1B Receptor
    Kazumi Koga, Mitsukane Yoshinaga, Yoshikatsu Uematsu, Yuji Nagai, Naoki Miyakoshi, Yoko Shimoda, Masayuki Fujinaga, Takafumi Minamimoto, Ming-Rong Zhang, Makoto Higuchi, Norikazu Ohtake, Tetsuya Suhara and Shigeyuki Chaki
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 495-508; DOI: https://doi.org/10.1124/jpet.116.232942
  • BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells
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    BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells
    David J. Lamb, Stefan Lutz Wollin, Andreas Schnapp, Daniel Bischoff, Klaus J. Erb, Thierry Bouyssou, Bernd Guilliard, Christine Strasser, Eva Wex, Sylvia Blum, Eva Thaler, Helga Nickel, Oliver Radmacher, Hannah Haas, Jennifer L. Swantek, Don Souza, Melissa Canfield, Della White, Mark Panzenbeck, Mohammed A. Kashem, Mary Sanville-Ross, Takeshi Kono, Katherina Sewald, Armin Braun, Helena Obernolte, Olga Danov, Gerhard Schaenzle, Georg Rast, Gerd-Michael Maier and Matthias Hoffmann
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 554-561; DOI: https://doi.org/10.1124/jpet.116.233155

Endocrine and Diabetes

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    In Vivo and In Vitro Characterization of Basal Insulin Peglispro: A Novel Insulin Analog
    Rebecca A. Owens, Ryan J. Hansen, Steven D. Kahl, Chen Zhang, Xiaoping Ruan, Anja Koester, Shun Li, Hui-Rong Qian, Mark W. Farmen, M. Dodson Michael, Julie S. Moyers, Gordon B. Cutler, Andrew Vick and John M. Beals
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 459-465; DOI: https://doi.org/10.1124/jpet.115.231035
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    Inhibition of the Inflammasome NLRP3 by Arglabin Attenuates Inflammation, Protects Pancreatic β-Cells from Apoptosis, and Prevents Type 2 Diabetes Mellitus Development in ApoE2Ki Mice on a Chronic High-Fat Diet
    Amna Abderrazak, Khadija El Hadri, Elodie Bosc, Bertrand Blondeau, Mohamed-Naceur Slimane, Berthold Büchele, Thomas Simmet, Dominique Couchie and Mustapha Rouis
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 487-494; DOI: https://doi.org/10.1124/jpet.116.232934

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Protection from Cigarette Smoke–Induced Lung Dysfunction and Damage by H2 Relaxin (Serelaxin)
    Alessandro Pini, Giulia Boccalini, Laura Lucarini, Stefano Catarinicchia, Daniele Guasti, Emanuela Masini, Daniele Bani and Silvia Nistri
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 451-458; DOI: https://doi.org/10.1124/jpet.116.232215
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    Enhanced Sensitivity of α3β4 Nicotinic Receptors in Enteric Neurons after Long-Term Morphine: Implication for Opioid-Induced Constipation
    Aravind R. Gade, Minho Kang, Fayez Khan, John R. Grider, M. Imad Damaj, William L. Dewey and Hamid I. Akbarali
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 520-528; DOI: https://doi.org/10.1124/jpet.116.233304
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    Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers
    Sumanta Kumar Goswami, Debin Wan, Jun Yang, Carlos A. Trindade da Silva, Christophe Morisseau, Sean D. Kodani, Guang-Yu Yang, Bora Inceoglu and Bruce D. Hammock
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 529-536; DOI: https://doi.org/10.1124/jpet.116.232108
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    Pharmacology of Bradykinin-Evoked Coughing in Guinea Pigs
    Matthew M. Hewitt, Gregory Adams, Stuart B. Mazzone, Nanako Mori, Li Yu and Brendan J. Canning
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 620-628; DOI: https://doi.org/10.1124/jpet.115.230383

Inflammation, Immunopharmacology, and Asthma

  • Open Access
    Tiotropium Attenuates Virus-Induced Pulmonary Inflammation in Cigarette Smoke–Exposed Mice
    Hannes Bucher, Matthias J. Duechs, Cornelia Tilp, Birgit Jung and Klaus J. Erb
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 606-618; DOI: https://doi.org/10.1124/jpet.116.232009

Metabolism, Transport, and Pharmacogenomics

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    Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal Microsomes
    Vyvyca J. Walker, Alisha P. Griffin, Dagan K. Hammar and Paul F. Hollenberg
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 537-544; DOI: https://doi.org/10.1124/jpet.116.232553

Neuropharmacology

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    Differential Potency of 2,6-Dimethylcyclohexanol Isomers for Positive Modulation of GABAA Receptor Currents
    Luvana Chowdhury, Celine J. Croft, Shikha Goel, Naina Zaman, Angela C.-S. Tai, Erin M. Walch, Kelly Smith, Alexandra Page, Kevin M. Shea, C. Dennis Hall, D. Jishkariani, Girinath G. Pillai and Adam C. Hall
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 570-579; DOI: https://doi.org/10.1124/jpet.115.228890
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    Notoginsenoside R1 Protects against Neonatal Cerebral Hypoxic-Ischemic Injury through Estrogen Receptor–Dependent Activation of Endoplasmic Reticulum Stress Pathways
    Yan Wang, Liu Tu, Yingbo Li, Di Chen and Shali Wang
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 591-605; DOI: https://doi.org/10.1124/jpet.115.230359

Erratum

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    Correction to “Combined Antiproliferative Effects of the Aminoalkylindole WIN55,212-2 and Radiation in Breast Cancer Cells”
    Journal of Pharmacology and Experimental Therapeutics June 2016, 357 (3) 619; DOI: https://doi.org/10.1124/jpet.113.205120err
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 357 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 357, Issue 3
1 Jun 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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Jump to

  • Minireview
  • Behavioral Pharmacology
  • Cardiovascular
  • Drug Discovery and Translational Medicine
  • Endocrine and Diabetes
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Inflammation, Immunopharmacology, and Asthma
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
  • Erratum
  • Most Cited
  • Most Read
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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