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Research ArticleMetabolism, Transport, and Pharmacogenomics

Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter

Kristin M. Bircsak, Vivek Gupta, Poi Yu Sofia Yuen, Ludwik Gorczyca, Barry I. Weinberger, Anna M. Vetrano and Lauren M. Aleksunes
Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 103-113; DOI: https://doi.org/10.1124/jpet.115.230185
Kristin M. Bircsak
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Vivek Gupta
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Poi Yu Sofia Yuen
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Ludwik Gorczyca
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Barry I. Weinberger
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Anna M. Vetrano
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Lauren M. Aleksunes
Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
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Article Information

vol. 357 no. 1 103-113
DOI 
https://doi.org/10.1124/jpet.115.230185
PubMed 
26850786

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received October 30, 2015
  • Accepted February 2, 2016
  • Published online March 14, 2016.

Article Versions

  • Earlier version (February 5, 2016 - 10:31).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kristin M. Bircsak,
  2. Vivek Gupta,
  3. Poi Yu Sofia Yuen,
  4. Ludwik Gorczyca,
  5. Barry I. Weinberger,
  6. Anna M. Vetrano, and
  7. Lauren M. Aleksunes
  1. Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy (K.M.B., L.M.A., L.G.), and Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey (L.M.A.), Piscataway, New Jersey; Departments of Obstetrics and Gynecology (V.G.) and Pediatrics (P.Y.S.Y., A.M.V.), Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey; Hofstra North Shore-LIJ School of Medicine, Cohen Children’s Medical Center of New York, New Hyde Park, New York (B.I.W.)
  1. Address correspondence to:
    Dr. Lauren Aleksunes, Dept of Pharmacology and Toxicology, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854. E-mail: aleksunes{at}eohsi.rutgers.edu
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Journal of Pharmacology and Experimental Therapeutics: 357 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 357, Issue 1
1 Apr 2016
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Research ArticleMetabolism, Transport, and Pharmacogenomics

Genistein Reduces Placental BCRP Function and Expression

Kristin M. Bircsak, Vivek Gupta, Poi Yu Sofia Yuen, Ludwik Gorczyca, Barry I. Weinberger, Anna M. Vetrano and Lauren M. Aleksunes
Journal of Pharmacology and Experimental Therapeutics April 1, 2016, 357 (1) 103-113; DOI: https://doi.org/10.1124/jpet.115.230185

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Genistein Reduces Placental BCRP Function and Expression

Kristin M. Bircsak, Vivek Gupta, Poi Yu Sofia Yuen, Ludwik Gorczyca, Barry I. Weinberger, Anna M. Vetrano and Lauren M. Aleksunes
Journal of Pharmacology and Experimental Therapeutics April 1, 2016, 357 (1) 103-113; DOI: https://doi.org/10.1124/jpet.115.230185
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