Journal of Pharmacology and Experimental Therapeutics: 357 (1)

April 01, 2016; Volume 357,Issue 1

Minireviews

You have access
The Pharmacological Basis of Cannabis Therapy for Epilepsy
Doodipala Samba Reddy and Victoria M. Golub

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 45-55; DOI: https://doi.org/10.1124/jpet.115.230151
You have access
Targeting Epigenetic Mechanisms for Chronic Pain: A Valid Approach for the Development of Novel Therapeutics
Casey O. Ligon, Rachel D. Moloney and Beverley Greenwood-Van Meerveld

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 84-93; DOI: https://doi.org/10.1124/jpet.115.231670

Behavioral Pharmacology

You have access
Characterization of the Discriminative Stimulus Effects of a NOP Receptor Agonist Ro 64-6198 in Rhesus Monkeys
Phillip A. Saccone, Kathy A. Zelenock, Angela M. Lindsey, Agnieszka Sulima, Kenner C. Rice, Eric P. Prinssen, Jürgen Wichmann and James H. Woods

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 17-23; DOI: https://doi.org/10.1124/jpet.115.231134
You have access
Comparisons of Δ⁹-Tetrahydrocannabinol and Anandamide on a Battery of Cognition-Related Behavior in Nonhuman Primates
Brian D. Kangas, Michael Z. Leonard, Vidyanand G. Shukla, Shakiru O. Alapafuja, Spyros P. Nikas, Alexandros Makriyannis and Jack Bergman

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 125-133; DOI: https://doi.org/10.1124/jpet.115.228189
You have access
The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model
Jenny L. Wilkerson, Micah J. Niphakis, Travis W. Grim, Mohammed A. Mustafa, Rehab A. Abdullah, Justin L. Poklis, William L. Dewey, Hamid Akbarali, Matthew L. Banks, Laura E. Wise, Benjamin F. Cravatt and Aron H. Lichtman

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 145-156; DOI: https://doi.org/10.1124/jpet.115.229971

Cardiovascular

You have access
Inhibition of K_V7 Channels Protects the Rat Heart against Myocardial Ischemia and Reperfusion Injury
Elise R. Hedegaard, Jacob Johnsen, Jonas A. Povlsen, Nichlas R. Jespersen, Jeffrey A. Shanmuganathan, Mia R. Laursen, Steen B. Kristiansen, Ulf Simonsen and Hans Erik Bøtker

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 94-102; DOI: https://doi.org/10.1124/jpet.115.230409

Cellular and Molecular

You have access
Ethanol Regulation of Synaptic GABA_A α4 Receptors Is Prevented by Protein Kinase A Activation
Stephen L. Carlson, John Peyton Bohnsack and A. Leslie Morrow

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 10-16; DOI: https://doi.org/10.1124/jpet.115.230417
You have access
Ligand-Independent Adenosine A_2B Receptor Constitutive Activity as a Promoter of Prostate Cancer Cell Proliferation
Elizabeth A. Vecchio, Christina Y. R. Tan, Karen J. Gregory, Arthur Christopoulos, Paul J. White and Lauren T. May

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 36-44; DOI: https://doi.org/10.1124/jpet.115.230003

Drug Discovery and Translational Medicine

You have access
5-HT₂ Receptor Regulation of Mitochondrial Genes: Unexpected Pharmacological Effects of Agonists and Antagonists
Jennifer L. Harmon, Lauren P. Wills, Caitlin E. McOmish, Elena Y. Demireva, Jay A. Gingrich, Craig C. Beeson and Rick G. Schnellmann

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 1-9; DOI: https://doi.org/10.1124/jpet.115.228395
You have access
Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine
Aaron Janowsky, Dilip K. Tosh, Amy J. Eshleman and Kenneth A. Jacobson

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 24-35; DOI: https://doi.org/10.1124/jpet.115.229666
You have access
Stronger Uricosuric Effects of the Novel Selective URAT1 Inhibitor UR-1102 Lowered Plasma Urate in Tufted Capuchin Monkeys to a Greater Extent than Benzbromarone
Sung Oh Ahn, Shuichi Ohtomo, Jumpei Kiyokawa, Toshito Nakagawa, Mizuki Yamane, Kyoung June Lee, Ki Hwan Kim, Byung Ho Kim, Jo Tanaka, Yoshiki Kawabe and Naoshi Horiba

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 157-166; DOI: https://doi.org/10.1124/jpet.115.231647
You have access
3,3′-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B–Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells
David M. Elliott, Mitzi Nagarkatti and Prakash S. Nagarkatti

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 177-187; DOI: https://doi.org/10.1124/jpet.115.226563

Endocrine and Diabetes

You have access
Fasiglifam/TAK-875, a Selective GPR40 Agonist, Improves Hyperglycemia in Rats Unresponsive to Sulfonylureas and Acts Additively with Sulfonylureas
Ryo Ito, Yoshiyuki Tsujihata, Masami Suzuki, Kazumasa Miyawaki, Kae Matsuda and Koji Takeuchi

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 217-227; DOI: https://doi.org/10.1124/jpet.115.230730

Gastrointestinal, Hepatic, Pulmonary, and Renal

Open Access
Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs
Emlyn Clay, Riccardo Patacchini, Marcello Trevisani, Delia Preti, Maria Pia Branà, Domenico Spina and Clive Page

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 73-83; DOI: https://doi.org/10.1124/jpet.115.230227

Inflammation, Immunopharmacology, and Asthma

You have access
Roflumilast Increases Bacterial Load and Dissemination in a Model of Pseudomononas Aeruginosa Airway Infection
Gopinath Kasetty, Praveen Papareddy, Ravi K.V. Bhongir and Arne Egesten

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 66-72; DOI: https://doi.org/10.1124/jpet.115.229641
You have access
Involvement of Extracellular Signal-Regulated Kinase 5 in Kinin B₁ Receptor Upregulation in Isolated Human Umbilical Veins
Yael Kilstein, Wanda Nowak, Andrea Emilse Errasti, Antía Andrea Barcia Feás, Arnaldo Raúl Armesto, Facundo Germán Pelorosso and Rodolfo Pedro Rothlin

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 114-124; DOI: https://doi.org/10.1124/jpet.115.230169

Metabolism, Transport, and Pharmacogenomics

You have access
Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter
Kristin M. Bircsak, Vivek Gupta, Poi Yu Sofia Yuen, Ludwik Gorczyca, Barry I. Weinberger, Anna M. Vetrano and Lauren M. Aleksunes

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 103-113; DOI: https://doi.org/10.1124/jpet.115.230185

Neuropharmacology

You have access
Cyclin-Dependent Kinase Inhibitor 1a (p21) Modulates Response to Cocaine and Motivated Behaviors
Natalie E. Scholpa, Sherri B. Briggs, John J. Wagner and Brian S. Cummings

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 56-65; DOI: https://doi.org/10.1124/jpet.115.230888
You have access
In Vitro Characterization of Psychoactive Substances at Rat, Mouse, and Human Trace Amine-Associated Receptor 1
Linda D. Simmler, Danièle Buchy, Sylvie Chaboz, Marius C. Hoener and Matthias E. Liechti

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 134-144; DOI: https://doi.org/10.1124/jpet.115.229765
You have access
Neurosteroid Structure-Activity Relationships for Functional Activation of Extrasynaptic δGABA_A Receptors
Chase Matthew Carver and Doodipala Samba Reddy

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 188-204; DOI: https://doi.org/10.1124/jpet.115.229302
You have access
Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer Pool
Eline M.T. van Maanen, Tamara J. van Steeg, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie A. Stone and Meindert Danhof

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 205-216; DOI: https://doi.org/10.1124/jpet.115.230565

Toxicology

You have access
Elucidation of the Mechanisms through Which the Reactive Metabolite Diclofenac Acyl Glucuronide Can Mediate Toxicity
Renato J. Scialis and José E. Manautou

Journal of Pharmacology and Experimental Therapeutics April 2016, 357 (1) 167-176; DOI: https://doi.org/10.1124/jpet.115.230755

Main menu

User menu

Search

Table of Contents

Minireviews

Behavioral Pharmacology

Cardiovascular

Cellular and Molecular

Drug Discovery and Translational Medicine

Endocrine and Diabetes

Gastrointestinal, Hepatic, Pulmonary, and Renal

Inflammation, Immunopharmacology, and Asthma

Metabolism, Transport, and Pharmacogenomics

Neuropharmacology

Toxicology

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals