Research ArticleChemotherapy, Antibiotics, and Gene Therapy
Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform
Brian B. Hasinoff, Xing Wu, Daywin Patel, Ragu Kanagasabai, Soumendrakrishna Karmahapatra and Jack C. Yalowich
Journal of Pharmacology and Experimental Therapeutics February 2016, 356 (2) 397-409; DOI: https://doi.org/10.1124/jpet.115.228650
Brian B. Hasinoff
College of Pharmacy, Apotex Centre, University of Manitoba, Winnipeg, Manitoba, Canada (B.B.H., X.W., D.P.); and Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus, Ohio (R.K., S.K., J.C.Y.)
Xing Wu
College of Pharmacy, Apotex Centre, University of Manitoba, Winnipeg, Manitoba, Canada (B.B.H., X.W., D.P.); and Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus, Ohio (R.K., S.K., J.C.Y.)
Daywin Patel
College of Pharmacy, Apotex Centre, University of Manitoba, Winnipeg, Manitoba, Canada (B.B.H., X.W., D.P.); and Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus, Ohio (R.K., S.K., J.C.Y.)
Ragu Kanagasabai
College of Pharmacy, Apotex Centre, University of Manitoba, Winnipeg, Manitoba, Canada (B.B.H., X.W., D.P.); and Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus, Ohio (R.K., S.K., J.C.Y.)
Soumendrakrishna Karmahapatra
College of Pharmacy, Apotex Centre, University of Manitoba, Winnipeg, Manitoba, Canada (B.B.H., X.W., D.P.); and Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus, Ohio (R.K., S.K., J.C.Y.)
Jack C. Yalowich
College of Pharmacy, Apotex Centre, University of Manitoba, Winnipeg, Manitoba, Canada (B.B.H., X.W., D.P.); and Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus, Ohio (R.K., S.K., J.C.Y.)
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Research ArticleChemotherapy, Antibiotics, and Gene Therapy
Mechanisms of the Reduced Cardiotoxicity of Pixantrone
Brian B. Hasinoff, Xing Wu, Daywin Patel, Ragu Kanagasabai, Soumendrakrishna Karmahapatra and Jack C. Yalowich
Journal of Pharmacology and Experimental Therapeutics February 1, 2016, 356 (2) 397-409; DOI: https://doi.org/10.1124/jpet.115.228650
Research ArticleChemotherapy, Antibiotics, and Gene Therapy
Mechanisms of the Reduced Cardiotoxicity of Pixantrone
Brian B. Hasinoff, Xing Wu, Daywin Patel, Ragu Kanagasabai, Soumendrakrishna Karmahapatra and Jack C. Yalowich
Journal of Pharmacology and Experimental Therapeutics February 1, 2016, 356 (2) 397-409; DOI: https://doi.org/10.1124/jpet.115.228650
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