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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Novel Epidermal Growth Factor Receptor Inhibitor Attenuates Angiotensin II–Induced Kidney Fibrosis

Yuanyuan Qian, Kesong Peng, Chenyu Qiu, Melissa Skibba, Yi Huang, Zheng Xu, Yali Zhang, Jie Hu, Dandan Liang, Chunpeng Zou, Yi Wang and Guang Liang
Journal of Pharmacology and Experimental Therapeutics January 2016, 356 (1) 32-42; DOI: https://doi.org/10.1124/jpet.115.228080
Yuanyuan Qian
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Kesong Peng
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Chenyu Qiu
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Melissa Skibba
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Yi Huang
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Zheng Xu
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Yali Zhang
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Jie Hu
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Dandan Liang
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Chunpeng Zou
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Yi Wang
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Guang Liang
Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
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Article Information

vol. 356 no. 1 32-42
DOI 
https://doi.org/10.1124/jpet.115.228080
PubMed 
26514795

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 25, 2015
  • Accepted October 27, 2015
  • Published online November 25, 2015.

Article Versions

  • Earlier version (October 29, 2015 - 09:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yuanyuan Qian,
  2. Kesong Peng,
  3. Chenyu Qiu,
  4. Melissa Skibba,
  5. Yi Huang,
  6. Zheng Xu,
  7. Yali Zhang,
  8. Jie Hu,
  9. Dandan Liang,
  10. Chunpeng Zou,
  11. Yi Wang, and
  12. Guang Liang
  1. Chemical Biology Research Center, School of Pharmaceutical Science (Y.Q., K.P., C.Q., M.S., Y.H., Z.X., Y.Z., J.H., D.L., Y.W., and G.L.); Department of Ultrasonography, 2nd Affiliated Hospital (C.Z.), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China
  1. Address correspondence to:
    Dr. Guang Liang, Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, People’s Republic of China. E-mail: wzmcliangguang{at}163.com
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Journal of Pharmacology and Experimental Therapeutics: 356 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 356, Issue 1
1 Jan 2016
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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

EGFR Inhibition Attenuates Kidney Fibrosis

Yuanyuan Qian, Kesong Peng, Chenyu Qiu, Melissa Skibba, Yi Huang, Zheng Xu, Yali Zhang, Jie Hu, Dandan Liang, Chunpeng Zou, Yi Wang and Guang Liang
Journal of Pharmacology and Experimental Therapeutics January 1, 2016, 356 (1) 32-42; DOI: https://doi.org/10.1124/jpet.115.228080

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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

EGFR Inhibition Attenuates Kidney Fibrosis

Yuanyuan Qian, Kesong Peng, Chenyu Qiu, Melissa Skibba, Yi Huang, Zheng Xu, Yali Zhang, Jie Hu, Dandan Liang, Chunpeng Zou, Yi Wang and Guang Liang
Journal of Pharmacology and Experimental Therapeutics January 1, 2016, 356 (1) 32-42; DOI: https://doi.org/10.1124/jpet.115.228080
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