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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

December 01, 2015; Volume 355,Issue 3

Highlighted Papers

  • You have access
    Magnesium Modifies the Impact of Calcitriol Treatment In Chronic Kidney Disease
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 351; DOI: https://doi.org/10.1124/jpet.115.1215HIa
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    Minimal Anticipated Biological Effect Level of Anti-CD28 Receptor Antagonist
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 351; DOI: https://doi.org/10.1124/jpet.115.1215HIc
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    Administration of Carvedilol Protects Against Doxorubicin-Induced Cardiomyopathy
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 351; DOI: https://doi.org/10.1124/jpet.115.1215HIb
  • You have access
    Directly Observable Behavioral Effects of Lorcaserin in Rats
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 351; DOI: https://doi.org/10.1124/jpet.115.1215HI

Commentary

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    Editor’s Note
    Michael F. Jarvis
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 352; DOI: https://doi.org/10.1124/jpet.115.229138

Minireviews

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    Cracking the Egg: Potential of the Developing Chicken as a Model System for Nonclinical Safety Studies of Pharmaceuticals
    Sigrid Bjørnstad, Lars Peter Engeset Austdal, Borghild Roald, Joel Clinton Glover and Ragnhild Elisabeth Paulsen
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 386-396; DOI: https://doi.org/10.1124/jpet.115.227025
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    Matrix Metalloproteinases as Regulators of Vein Structure and Function: Implications in Chronic Venous Disease
    Elisabeth MacColl and Raouf A. Khalil
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 410-428; DOI: https://doi.org/10.1124/jpet.115.227330

Behavioral Pharmacology

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    Directly Observable Behavioral Effects of Lorcaserin in Rats
    Katherine M. Serafine, Kenner C. Rice and Charles P. France
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 381-385; DOI: https://doi.org/10.1124/jpet.115.228148
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    The M1 Muscarinic Positive Allosteric Modulator PQCA Improves Performance on Translatable Tests of Memory and Attention in Rhesus Monkeys
    Henry S. Lange, Christopher E. Cannon, Jason T. Drott, Scott D. Kuduk and Jason M. Uslaner
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 442-450; DOI: https://doi.org/10.1124/jpet.115.226712

Cardiovascular

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    Magnesium Modifies the Impact of Calcitriol Treatment on Vascular Calcification in Experimental Chronic Kidney Disease
    Jason G. E. Zelt, Kristin M. McCabe, Bruno Svajger, Henry Barron, Kim Laverty, Rachel M. Holden and Michael A. Adams
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 451-462; DOI: https://doi.org/10.1124/jpet.115.228106
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    Early Administration of Carvedilol Protected against Doxorubicin-Induced Cardiomyopathy
    Yung-Lung Chen, Sheng-Ying Chung, Han-Tan Chai, Chih-Hung Chen, Chu-Feng Liu, Yi-Ling Chen, Tien-Hung Huang, Yen-Yi Zhen, Pei-Hsun Sung, Cheuk-Kwan Sun, Sarah Chua, Hung-I Lu, Fan-Yen Lee, Jiunn-Jye Sheu and Hon-Kan Yip
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 516-527; DOI: https://doi.org/10.1124/jpet.115.225375

Drug Discovery and Translational Medicine

  • LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity
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    LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity
    Min Qin, Shihong Peng, Ning Liu, Meichun Hu, Yundong He, Guoliang Li, Huang Chen, Yuan He, Ang Chen, Xin Wang, Mingyao Liu, Yihua Chen and Zhengfang Yi
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 473-483; DOI: https://doi.org/10.1124/jpet.115.225912
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    Integrated Pharmacokinetic/Pharmacodynamic Analysis for Determining the Minimal Anticipated Biological Effect Level of a Novel Anti-CD28 Receptor Antagonist BMS-931699
    Zheng Yang, Haiqing Wang, Theodora W. Salcedo, Suzanne J. Suchard, Jenny H. Xie, Lumelle A. Schneeweis, Catherine A. Fleener, James D. Calore, Rong Shi, Sean X.Y. Zhang, A. David Rodrigues, Bruce D. Car, Punit H. Marathe and Steven G. Nadler
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 506-515; DOI: https://doi.org/10.1124/jpet.115.227249

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Autophagy Deficiency Diminishes Indomethacin-Induced Intestinal Epithelial Cell Damage through Activation of the ERK/Nrf2/HO-1 Pathway
    Satoshi Harada, Takatoshi Nakagawa, Shunichi Yokoe, Shoko Edogawa, Toshihisa Takeuchi, Takuya Inoue, Kazuhide Higuchi and Michio Asahi
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 353-361; DOI: https://doi.org/10.1124/jpet.115.226431
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    Cinnamamides, Novel Liver X Receptor Antagonists that Inhibit Ligand-Induced Lipogenesis and Fatty Liver
    Woo-Cheol Sim, Dong Gwang Kim, Kyeong Jin Lee, You-Jin Choi, Yeon Jae Choi, Kye Jung Shin, Dae Won Jun, So-Jung Park, Hyun-Ju Park, Jiwon Kim, Won Keun Oh and Byung-Hoon Lee
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 362-369; DOI: https://doi.org/10.1124/jpet.115.226738

Inflammation, Immunopharmacology, and Asthma

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    NLRP3 Inflammasome Involvement in the Organ Damage and Impaired Spermatogenesis Induced by Testicular Ischemia and Reperfusion in Mice
    Letteria Minutoli, Pietro Antonuccio, Natasha Irrera, Mariagrazia Rinaldi, Alessandra Bitto, Herbert Marini, Gabriele Pizzino, Carmelo Romeo, Antonina Pisani, Giuseppe Santoro, Domenico Puzzolo, Carlo Magno, Francesco Squadrito, Antonio Micali and Domenica Altavilla
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 370-380; DOI: https://doi.org/10.1124/jpet.115.226936

Metabolism, Transport, and Pharmacogenomics

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    Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes
    Elizabeth A. Rondini, Asmita Pant and Thomas A. Kocarek
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 429-441; DOI: https://doi.org/10.1124/jpet.115.226365

Neuropharmacology

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    MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition
    Matthew J. Fell, Christian Mirescu, Kallol Basu, Boonlert Cheewatrakoolpong, Duane E. DeMong, J. Michael Ellis, Lynn A. Hyde, Yinghui Lin, Carrie G. Markgraf, Hong Mei, Michael Miller, Frederique M. Poulet, Jack D. Scott, Michelle D. Smith, Zhizhang Yin, Xiaoping Zhou, Eric M. Parker, Matthew E. Kennedy and John A. Morrow
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 397-409; DOI: https://doi.org/10.1124/jpet.115.227587
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    Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits
    Paula L. Vieira-Brock, Lisa M. McFadden, Shannon M. Nielsen, Jonathan D. Ellis, Elliot T. Walters, Kristen A. Stout, J. Michael McIntosh, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 463-472; DOI: https://doi.org/10.1124/jpet.114.221945
  • Inhibition of Plasma Membrane Na/Ca-Exchanger by KB-R7943 or Lithium Reveals Its Role in Ca-Dependent <em>N</em>-methyl-<span class="sc">d</span>-aspartate Receptor Inactivation
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    Inhibition of Plasma Membrane Na/Ca-Exchanger by KB-R7943 or Lithium Reveals Its Role in Ca-Dependent N-methyl-d-aspartate Receptor Inactivation
    Dmitry A. Sibarov, Polina A. Abushik, Ekaterina E. Poguzhelskaya, Konstantin V. Bolshakov and Sergei M. Antonov
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 484-495; DOI: https://doi.org/10.1124/jpet.115.227173
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    Phosphorylation of the N-methyl-d-aspartate receptor is increased in the nucleus accumbens during both acute and extended morphine withdrawal
    Ethan M. Anderson, Turi Reeves, Katherine Kapernaros, John K. Neubert and Robert M. Caudle
    Journal of Pharmacology and Experimental Therapeutics December 2015, 355 (3) 496-505; DOI: https://doi.org/10.1124/jpet.115.227629
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Journal of Pharmacology and Experimental Therapeutics: 355 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 355, Issue 3
1 Dec 2015
  • Table of Contents
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