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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

October 01, 2015; Volume 355,Issue 1

Announcement

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    Announcement
    Mary Vore
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 135; DOI: https://doi.org/10.1124/jpet.115.229096

Highlighted Papers

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    Potent and Selective Inhibitors of Human Leukotriene C4 Synthase
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 1; DOI: https://doi.org/10.1124/jpet.115.1015HIc
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    Biodistribution Impacts Lung Anti-Inflammatory Efficacy of PKC-Delta Peptide
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 1; DOI: https://doi.org/10.1124/jpet.115.1015HIb
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    Sphingosine Kinase 2 Inhibition and Blood Sphingosine Kinase 1-Phosphate Levels
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 1; DOI: https://doi.org/10.1124/jpet.115.1015HIa
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    The Prodrug 4-Chlorokynurenine Causes Antidepressant Effects
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 1; DOI: https://doi.org/10.1124/jpet.115.1015HI

Behavioral Pharmacology

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    The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition
    Panos Zanos, Sean C. Piantadosi, Hui-Qiu Wu, Heather J. Pribut, Matthew J. Dell, Adem Can, H. Ralph Snodgrass, Carlos A. Zarate, Robert Schwarcz and Todd D. Gould
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 76-85; DOI: https://doi.org/10.1124/jpet.115.225664

Cardiovascular

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    Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide–High Angiotensin II–Induced Cardiovascular Injury
    Luminita H. Pojoga, Tham M. Yao, Lauren A. Opsasnick, Waleed T. Siddiqui, Ossama M. Reslan, Gail K. Adler, Gordon H. Williams and Raouf A. Khalil
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 32-47; DOI: https://doi.org/10.1124/jpet.115.226043
  • A Novel Arginase Inhibitor Derived from <em>Scutellavia indica</em> Restored Endothelial Function in ApoE-Null Mice Fed a High-Cholesterol Diet
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    A Novel Arginase Inhibitor Derived from Scutellavia indica Restored Endothelial Function in ApoE-Null Mice Fed a High-Cholesterol Diet
    Hye Mi Hwang, Jeong Hyung Lee, Byung Sun Min, Byeong Hwa Jeon, Kwang Lae Hoe, Young Myeong Kim and Sungwoo Ryoo
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 57-65; DOI: https://doi.org/10.1124/jpet.115.224592

Cellular and Molecular

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    Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels
    Yugesh Kharel, Emily A. Morris, Molly D. Congdon, Steven B. Thorpe, Jose L. Tomsig, Webster L. Santos and Kevin R. Lynch
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 23-31; DOI: https://doi.org/10.1124/jpet.115.225862

Drug Discovery and Translational Medicine

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    Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains
    Kurt Giles, David B. Berry, Carlo Condello, Ronald C. Hawley, Alejandra Gallardo-Godoy, Clifford Bryant, Abby Oehler, Manuel Elepano, Sumita Bhardwaj, Smita Patel, B. Michael Silber, Shenheng Guan, Stephen J. DeArmond, Adam R. Renslo and Stanley B. Prusiner
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 2-12; DOI: https://doi.org/10.1124/jpet.115.224659

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Pharmacological In Vivo Inhibition of S-Nitrosoglutathione Reductase Attenuates Bleomycin-Induced Inflammation and Fibrosis
    Irina G. Luzina, Virginia Lockatell, Nevins W. Todd, Pavel Kopach, Helen S. Pentikis and Sergei P. Atamas
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 13-22; DOI: https://doi.org/10.1124/jpet.115.224675
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    MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux
    Boris Tchernychev, Pei Ge, Marco M. Kessler, Robert M. Solinga, Derek Wachtel, Jenny V. Tobin, Sara R. Thomas, Craig E. Lunte, Angelika Fretzen, Gerhard Hannig, Alexander P. Bryant, Caroline B. Kurtz, Mark G. Currie and Inmaculada Silos-Santiago
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 48-56; DOI: https://doi.org/10.1124/jpet.115.224329
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    The Impact of Spironolactone on the Severity of Portal-Systemic Collaterals and Hepatic Encephalopathy in Cirrhotic Rats
    Shao-Jung Hsu, Sun-Sang Wang, Teh-Ia Huo, Fa-Yauh Lee, Hui-Chun Huang, Ching-Chih Chang, I-Fang Hsin, Hsin-Ling Ho, Han-Chieh Lin and Shou-Dong Lee
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 117-124; DOI: https://doi.org/10.1124/jpet.115.225516

Inflammation, Immunopharmacology, and Asthma

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    HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid
    Christeene G. Haj, Percy F. Sumariwalla, Lumír Hanuš, Natalya M. Kogan, Zhana Yektin, Raphael Mechoulam, Mark Feldmann and Ruth Gallily
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 66-75; DOI: https://doi.org/10.1124/jpet.115.226100
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    Biodistribution and Efficacy of Targeted Pulmonary Delivery of a Protein Kinase C-δ Inhibitory Peptide: Impact on Indirect Lung Injury
    Mark J. Mondrinos, Linda C. Knight, Paul A. Kennedy, Jichuan Wu, Matthew Kauffman, Sandy T. Baker, Marla R. Wolfson and Laurie E. Kilpatrick
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 86-98; DOI: https://doi.org/10.1124/jpet.115.224832
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    Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase
    Thea K. Kleinschmidt, Martin Haraldsson, Devaraj Basavarajappa, Erik Lundeberg, Madhuranayaki Thulasingam, Maria Ekoff, Alexander Fauland, Christoph Lehmann, Astrid S. Kahnt, Lennart Lindbom and Jesper Z. Haeggström
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 108-116; DOI: https://doi.org/10.1124/jpet.115.227157

Metabolism, Transport, and Pharmacogenomics

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    P-Glycoprotein Transport of Neurotoxic Pesticides
    Sarah E. Lacher, Kasse Skagen, Joachim Veit, Rachel Dalton and Erica L. Woodahl
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 99-107; DOI: https://doi.org/10.1124/jpet.115.226373
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    The Drug-Drug Effects of Rhein on the Pharmacokinetics and Pharmacodynamics of Clozapine in Rat Brain Extracellular Fluid by In Vivo Microdialysis
    Mei-Ling Hou, Chi-Hung Lin, Lie-Chwen Lin and Tung-Hu Tsai
    Journal of Pharmacology and Experimental Therapeutics October 2015, 355 (1) 125-134; DOI: https://doi.org/10.1124/jpet.115.225763
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Journal of Pharmacology and Experimental Therapeutics: 355 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 355, Issue 1
1 Oct 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Inflammation, Immunopharmacology, and Asthma
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  • Potential Clinical Uses of CBG
  • Ocular Drug Delivery: Past, Present, and Future
  • Rho GTPase–Pathway Inhibitor Reduces Markers of Fibrosis
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