Journal of Pharmacology and Experimental Therapeutics: 354 (1)

July 01, 2015; Volume 354,Issue 1

Announcement

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ASPET Journals Support the National Institutes of Health Principles and Guidelines for Reporting Preclinical Research
Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 88-89; DOI: https://doi.org/10.1124/jpet.115.225995

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Intestinal Epithelium-Specific Knockout of P450 Exacerbates Colitis
Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0715HIc
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Altering Metabolic Profiles of Drugs with Precision Deuteration
Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0715HIa
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ATP-Sensitive Potassium Channel Activation Induces Angiogenesis
Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0715HI
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Chronopharmacology of Antiallodynic Effects of Pregabalin
Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0715HIb

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Targeting IL-33 in Autoimmunity and Inflammation
Theoharis C. Theoharides, Anastasia I. Petra, Alexandra Taracanova, Smaro Panagiotidou and Pio Conti

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 24-31; DOI: https://doi.org/10.1124/jpet.114.222505
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Viral and Other Cell-Penetrating Peptides as Vectors of Therapeutic Agents in Medicine
Julia Durzyńska, Łucja Przysiecka, Robert Nawrot, Jakub Barylski, Grzegorz Nowicki, Alicja Warowicka, Oskar Musidlak and Anna Goździcka-Józefiak

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 32-42; DOI: https://doi.org/10.1124/jpet.115.223305

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DSR-71167, a Novel Mineralocorticoid Receptor Antagonist with Carbonic Anhydrase Inhibitory Activity, Separates Urinary Sodium Excretion and Serum Potassium Elevation in Rats
Tetsuro Nariai, Katsuya Fujita, Kenji Kawane, Masaya Mori, Ryo Nakayama, Koichi Matsuda, Seiji Katayama, Nobuhisa Fukuda, Seiji Hori, Masato Iwata, Futoshi Hasegawa, Kuniko Suzuki and Hiroshi Kato

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 2-9; DOI: https://doi.org/10.1124/jpet.114.221341
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ATP-Sensitive Potassium Channel Activation Induces Angiogenesis In Vitro and In Vivo
Bukar Umaru, Anastasia Pyriochou, Vasileios Kotsikoris, Andreas Papapetropoulos and Stavros Topouzis

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 79-87; DOI: https://doi.org/10.1124/jpet.114.222000

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Altering Metabolic Profiles of Drugs by Precision Deuteration: Reducing Mechanism-Based Inhibition of CYP2D6 by Paroxetine
Vinita Uttamsingh, Richard Gallegos, Julie F. Liu, Scott L. Harbeson, Gary W. Bridson, Changfu Cheng, David S. Wells, Philip B. Graham, Robert Zelle and Roger Tung

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 43-54; DOI: https://doi.org/10.1124/jpet.115.223768
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Semimechanistic Cell-Cycle Type–Based Pharmacokinetic/Pharmacodynamic Model of Chemotherapy-Induced Neutropenic Effects of Diflomotecan under Different Dosing Schedules
Víctor Mangas-Sanjuan, Núria Buil-Bruna, María J. Garrido, Elena Soto and Iñaki F. Trocóniz

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 55-64; DOI: https://doi.org/10.1124/jpet.115.223776
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Humanized Thymidine Kinase–NOG Mice Can Be Used to Identify Drugs That Cause Animal-Specific Hepatotoxicity: A Case Study with Furosemide
Dan Xu, Sara A. Michie, Ming Zheng, Saori Takeda, Manhong Wu and Gary Peltz

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 73-78; DOI: https://doi.org/10.1124/jpet.115.224493

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Dosing Time-Dependent Changes in the Analgesic Effect of Pregabalin on Diabetic Neuropathy in Mice
Takahiro Akamine, Satoru Koyanagi, Naoki Kusunose, Hana Hashimoto, Marie Taniguchi, Naoya Matsunaga and Shigehiro Ohdo

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 65-72; DOI: https://doi.org/10.1124/jpet.115.223891

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Intestinal Epithelium–Specific Knockout of the Cytochrome P450 Reductase Gene Exacerbates Dextran Sulfate Sodium–Induced Colitis
Yi Zhu, Fang Xie, Liang Ding, Xiaoyu Fan, Xinxin Ding and Qing-Yu Zhang

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 10-17; DOI: https://doi.org/10.1124/jpet.115.223263

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Different Mechanisms for Histone Acetylation by Ethanol and Its Metabolite Acetate in Rat Primary Hepatocytes
Shivendra D. Shukla, Ricardo Restrepo, Philip Fish, Robert W. Lim and Jamal A. Ibdah

Journal of Pharmacology and Experimental Therapeutics July 2015, 354 (1) 18-23; DOI: https://doi.org/10.1124/jpet.115.223867