Research ArticleInflammation, Immunopharmacology, and Asthma
Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor
Igor A. Schepetkin, Liliya N. Kirpotina, Deepa Hammaker, Irina Kochetkova, Andrei I. Khlebnikov, Sergey A. Lyakhov, Gary S. Firestein and Mark T. Quinn
Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 505-516; DOI: https://doi.org/10.1124/jpet.114.220251
Igor A. Schepetkin
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Liliya N. Kirpotina
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Deepa Hammaker
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Irina Kochetkova
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Andrei I. Khlebnikov
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Sergey A. Lyakhov
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Gary S. Firestein
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
Mark T. Quinn
Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)
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In this issue
Research ArticleInflammation, Immunopharmacology, and Asthma
Inhibition of Collagen-Induced Arthritis by IQ-1S
Igor A. Schepetkin, Liliya N. Kirpotina, Deepa Hammaker, Irina Kochetkova, Andrei I. Khlebnikov, Sergey A. Lyakhov, Gary S. Firestein and Mark T. Quinn
Journal of Pharmacology and Experimental Therapeutics June 1, 2015, 353 (3) 505-516; DOI: https://doi.org/10.1124/jpet.114.220251
Research ArticleInflammation, Immunopharmacology, and Asthma
Inhibition of Collagen-Induced Arthritis by IQ-1S
Igor A. Schepetkin, Liliya N. Kirpotina, Deepa Hammaker, Irina Kochetkova, Andrei I. Khlebnikov, Sergey A. Lyakhov, Gary S. Firestein and Mark T. Quinn
Journal of Pharmacology and Experimental Therapeutics June 1, 2015, 353 (3) 505-516; DOI: https://doi.org/10.1124/jpet.114.220251
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