Journal of Pharmacology and Experimental Therapeutics: 353 (3)

June 01, 2015; Volume 353,Issue 3

Highlighted Papers

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N-Methyl-d-Aspartate Receptor Coagonists and Cocaine-Induced Conditioned Place Preference
Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 445; DOI: https://doi.org/10.1124/jpet.115.0615HI
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Inhibition of Collagen-Induced Arthritis by a c-Jun N-Terminal Kinase Inhibitor
Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 445; DOI: https://doi.org/10.1124/jpet.115.0615HIa
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Identification of Novel Allosteric Dopamine Transporter Ligands
Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 445; DOI: https://doi.org/10.1124/jpet.115.0615HIb
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Mechanism of Midazolam Antiseizure Activity
Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 445; DOI: https://doi.org/10.1124/jpet.115.0615HIc

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Trapping Poly(ADP-Ribose) Polymerase
Yuqiao Shen, Mika Aoyagi-Scharber and Bing Wang

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 446-457; DOI: https://doi.org/10.1124/jpet.114.222448
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Arsenic, Reactive Oxygen, and Endothelial Dysfunction
David C. Ellinsworth

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 458-464; DOI: https://doi.org/10.1124/jpet.115.223289

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Availability of N-Methyl-d-Aspartate Receptor Coagonists Affects Cocaine-Induced Conditioned Place Preference and Locomotor Sensitization: Implications for Comorbid Schizophrenia and Substance Abuse
Matthew D. Puhl, Alexandra R. Berg, Anita J. Bechtholt and Joseph T. Coyle

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 465-470; DOI: https://doi.org/10.1124/jpet.115.223099
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Donepezil Reverses Intermittent Stress-Induced Generalized Chronic Pain Syndrome in Mice
Takehiro Mukae, Hitoshi Uchida and Hiroshi Ueda

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 471-479; DOI: https://doi.org/10.1124/jpet.114.222414

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Ranolazine Reduces Remodeling of the Right Ventricle and Provoked Arrhythmias in Rats with Pulmonary Hypertension
John T. Liles, Kirsten Hoyer, Jason Oliver, Liguo Chi, Arvinder K. Dhalla and Luiz Belardinelli

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 480-489; DOI: https://doi.org/10.1124/jpet.114.221861
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Inhibition of Extracellular Cyclophilins with Cyclosporine Analog and Development of Atherosclerosis in Apolipoprotein E–Deficient Mice
Michael Ditiatkovski, Vijaya N. L. V. Neelisetti, Huanhuan L. Cui, Miroslav Malesevic, Gunter Fischer, Michael Bukrinsky and Dmitri Sviridov

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 490-495; DOI: https://doi.org/10.1124/jpet.115.223420

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A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor γ with Excellent Effect on Insulin Resistance and Type 2 Diabetes
Hui-juan Liu, Cheng-yu Zhang, Fei Song, Ting Xiao, Jing Meng, Qiang Zhang, Cai-li Liang, Shan Li, Jing Wang, Bo Zhang, Yan-rong Liu, Tao Sun and Hong-gang Zhou

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 573-581; DOI: https://doi.org/10.1124/jpet.115.223107

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Synergistic Effects of a GPR119 Agonist with Metformin on Weight Loss in Diet-Induced Obese Mice
Kamal Al-Barazanji, Judi McNulty, Jane Binz, Claudia Generaux, William Benson, Andrew Young and Lihong Chen

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 496-504; DOI: https://doi.org/10.1124/jpet.115.222828

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Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor
Igor A. Schepetkin, Liliya N. Kirpotina, Deepa Hammaker, Irina Kochetkova, Andrei I. Khlebnikov, Sergey A. Lyakhov, Gary S. Firestein and Mark T. Quinn

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 505-516; DOI: https://doi.org/10.1124/jpet.114.220251
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Curcumin Analog L48H37 Prevents Lipopolysaccharide-Induced TLR4 Signaling Pathway Activation and Sepsis via Targeting MD2
Yi Wang, Xiaoou Shan, Yuanrong Dai, Lili Jiang, Gaozhi Chen, Yali Zhang, Zhe Wang, Lili Dong, Jianzhang Wu, Guilong Guo and Guang Liang

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 539-550; DOI: https://doi.org/10.1124/jpet.115.222570
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Endothelin Receptor B Protects Granulocyte Macrophage Colony-Stimulating Factor mRNA from Degradation
David Jungck, Jürgen Knobloch, Sandra Körber, Yingfeng Lin, Jürgen Konradi, Sarah Yanik, Erich Stoelben and Andrea Koch

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 564-572; DOI: https://doi.org/10.1124/jpet.114.215822

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Antiseizure Activity of Midazolam in Mice Lacking δ-Subunit Extrasynaptic GABA_A Receptors
Sandesh D. Reddy, Iyan Younus, Bryan L. Clossen and Doodipala Samba Reddy

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 517-528; DOI: https://doi.org/10.1124/jpet.114.222075
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Studies of the Biogenic Amine Transporters 15. Identification of Novel Allosteric Dopamine Transporter Ligands with Nanomolar Potency
Richard B. Rothman, Subramaniam Ananthan, John S. Partilla, Surendra K. Saini, Omar Moukha-Chafiq, Vibha Pathak and Michael H. Baumann

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 529-538; DOI: https://doi.org/10.1124/jpet.114.222299
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Amiloride and GMQ Allosteric Modulation of the GABA-A ρ1 Receptor: Influences of the Intersubunit Site
Heather D. Snell and Eric B. Gonzales

Journal of Pharmacology and Experimental Therapeutics June 2015, 353 (3) 551-559; DOI: https://doi.org/10.1124/jpet.115.222802