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Research ArticleDrug Discovery and Translational Medicine

Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist

David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

Article Information

vol. 353 no. 2 340-350
DOI 
https://doi.org/10.1124/jpet.114.221358
PubMed 
25736418
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 10, 2014
  • Accepted February 27, 2015
  • Published online March 26, 2015.

Article Versions

Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. David J. Nicholls,
  2. Katherine Wiley1,
  3. Ian Dainty,
  4. Fraser MacIntosh2,
  5. Caroline Phillips,
  6. Alasdair Gaw3, and
  7. Carina Kärrman Mårdh
  1. Departments of Discovery Sciences (D.J.N.) and Oncology (C.P.), AstraZeneca R&D, Alderley Park, United Kingdom; Biosciences, AstraZeneca R&D Charnwood, Loughborough, Leicestershire, United Kingdom (K.W., F.M., A.G.); and Biosciences, AstraZeneca R&D, Mölndal, Sweden (I.D., C.K.M.)
  1. Address correspondence to:
    Carina Kärrman Mårdh, AstraZeneca R&D Mölndal, Pepparedsleden 1, Mölndal S-43183, Sweden. E-mail: carina.karrman-mardh{at}astrazeneca.com
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Research ArticleDrug Discovery and Translational Medicine

Pharmacology of AZD5069, a CXCR2 Antagonist

David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
Journal of Pharmacology and Experimental Therapeutics May 1, 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358
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