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Index by author

May 01, 2015; Volume 353,Issue 2

A

  1. Abdullah, Rehab

    1. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

  2. Ahn, Kay

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

B

  1. Bailey-Downs, Lora C.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  2. Bankstahl, J. P.

    1. Pilocarpine-Induced Convulsive Activity Is Limited by Multidrug Transporters at the Rodent Blood-Brain Barrier
      K. Römermann, J. P. Bankstahl, W. Löscher and M. Bankstahl
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 351-359; DOI: https://doi.org/10.1124/jpet.114.221952

  3. Bankstahl, M.

    1. Pilocarpine-Induced Convulsive Activity Is Limited by Multidrug Transporters at the Rodent Blood-Brain Barrier
      K. Römermann, J. P. Bankstahl, W. Löscher and M. Bankstahl
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 351-359; DOI: https://doi.org/10.1124/jpet.114.221952

  4. Barker-Haliski, Melissa L.

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

  5. Bastian, Anja

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  6. Bell, Sammy

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  7. Bobrowski, Walter

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  8. Boger, Elin

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

  9. Bonin, Paul D.

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  10. Brouwer, Kim L. R.

    1. Species Differences in Hepatobiliary Disposition of Taurocholic Acid in Human and Rat Sandwich-Cultured Hepatocytes: Implications for Drug-Induced Liver Injury
      Kyunghee Yang, Nathan D. Pfeifer, Kathleen Köck and Kim L. R. Brouwer
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 415-423; DOI: https://doi.org/10.1124/jpet.114.221564

  11. Buckbinder, Leonard

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

C

  1. Calani, Luca

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  2. Castrop, Hayo

    1. In Vivo Visualization of the Antialbuminuric Effects of the Angiotensin-Converting Enzyme Inhibitor Enalapril
      Ina Maria Schießl, Veronika Kattler and Hayo Castrop
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 299-306; DOI: https://doi.org/10.1124/jpet.114.222125

  3. Chappell, Michael

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

  4. Christopoulos, Arthur

    1. Endogenous Allosteric Modulators of G Protein–Coupled Receptors
      Emma T. van der Westhuizen, Celine Valant, Patrick M. Sexton and Arthur Christopoulos
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 246-260; DOI: https://doi.org/10.1124/jpet.114.221606

  5. Cortes, Christian

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  6. Coskran, Timothy

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  7. Cravatt, Benjamin F.

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836
    2. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

D

  1. Dahle, E. Jill

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

  2. Dainty, Ian

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  3. Dávalos, Alberto

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  4. Del Rio, Daniele

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  5. Devambatla, Ravi K. V.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  6. Disch, Bryan C.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  7. Donaldson, Cynthia J.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

E

  1. E. Zumbrun, Elizabeth

    1. Protective Role of Cannabinoid Receptor 2 Activation in Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure through Regulation of Macrophage Polarization and MicroRNAs
      Sunil Tomar, Elizabeth E. Zumbrun, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 369-379; DOI: https://doi.org/10.1124/jpet.114.220368

  2. Erchegyi, Judit

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  3. Eriksson, Ulf G.

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

  4. Espín, Juan Carlos

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  5. Evans, Neil

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

  6. Ewing, Pär

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

F

  1. Fancher, R. Marcus

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  2. Farmer, Luc

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  3. Fihn, Britt-Marie

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

  4. Fridén, Markus

    1. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships
      Elin Boger, Pär Ewing, Ulf G. Eriksson, Britt-Marie Fihn, Michael Chappell, Neil Evans and Markus Fridén
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 279-287; DOI: https://doi.org/10.1124/jpet.114.221226

G

  1. Gangjee, Aleem

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  2. Gaw, Alasdair

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  3. Giuffrida, Andrea

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836

  4. Gómez de Cedrón, Marta

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  5. González-Sarrías, Antonio

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  6. González-Vallinas, Margarita

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

H

  1. Heck, Taylor D.

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

  2. Henthorn, Jim

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  3. Heulens, Nele

    1. Innate Immune Modulation in Chronic Obstructive Pulmonary Disease: Moving Closer toward Vitamin D Therapy
      Nele Heulens, Hannelie Korf and Wim Janssens
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 360-368; DOI: https://doi.org/10.1124/jpet.115.223032

  4. Hogan, James K.

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  5. Hoock, Thomas C.

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  6. Hruba, Lenka

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836

  7. Humphries, Kenneth M.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

I

  1. Ignatowska-Jankowska, Bogna

    1. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

  2. Ihnat, Michael A.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  3. Iyer, Ramaswamy

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

J

  1. Janssens, Wim

    1. Innate Immune Modulation in Chronic Obstructive Pulmonary Disease: Moving Closer toward Vitamin D Therapy
      Nele Heulens, Hannelie Korf and Wim Janssens
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 360-368; DOI: https://doi.org/10.1124/jpet.115.223032

  2. Johnson, Kent

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

K

  1. Kalgutkar, Amit

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  2. Kapoor, Bhupesh

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  3. Kashiwagi, Hitoshi

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

  4. Kattler, Veronika

    1. In Vivo Visualization of the Antialbuminuric Effects of the Angiotensin-Converting Enzyme Inhibitor Enalapril
      Ina Maria Schießl, Veronika Kattler and Hayo Castrop
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 299-306; DOI: https://doi.org/10.1124/jpet.114.222125

  5. Kawabe, Thomas

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  6. Köck, Kathleen

    1. Species Differences in Hepatobiliary Disposition of Taurocholic Acid in Human and Rat Sandwich-Cultured Hepatocytes: Implications for Drug-Induced Liver Injury
      Kyunghee Yang, Nathan D. Pfeifer, Kathleen Köck and Kim L. R. Brouwer
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 415-423; DOI: https://doi.org/10.1124/jpet.114.221564

  7. Kojima, Fumiaki

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

  8. Korf, Hannelie

    1. Innate Immune Modulation in Chronic Obstructive Pulmonary Disease: Moving Closer toward Vitamin D Therapy
      Nele Heulens, Hannelie Korf and Wim Janssens
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 360-368; DOI: https://doi.org/10.1124/jpet.115.223032

  9. Kumei, Shima

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

L

  1. Lai, Yurong

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  2. Lewis, Kathy A.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  3. Li, Lun

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  4. Lichtman, Aron H.

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836
    2. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

  5. Liu, Tongtong

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  6. Löscher, W.

    1. Pilocarpine-Induced Convulsive Activity Is Limited by Multidrug Transporters at the Rodent Blood-Brain Barrier
      K. Römermann, J. P. Bankstahl, W. Löscher and M. Bankstahl
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 351-359; DOI: https://doi.org/10.1124/jpet.114.221952

M

  1. MacIntosh, Fraser

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  2. Mahajan, Sudipta

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  3. Marathe, Punit

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  4. Mårdh, Carina Kärrman

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  5. Martín-Hernández, Roberto

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  6. Martínez-Romero, Jorge

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  7. Maurer, Tristan S.

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  8. McMahon, Lance R.

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836

  9. Miller, Charleen

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  10. Mintier, Gabe

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  11. Molina, Susana

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  12. Mustafa, Mohammed

    1. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

N

  1. Nagarkatti, Mitzi

    1. Protective Role of Cannabinoid Receptor 2 Activation in Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure through Regulation of Macrophage Polarization and MicroRNAs
      Sunil Tomar, Elizabeth E. Zumbrun, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 369-379; DOI: https://doi.org/10.1124/jpet.114.220368

  2. Nagarkatti, Prakash S.

    1. Protective Role of Cannabinoid Receptor 2 Activation in Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure through Regulation of Macrophage Polarization and MicroRNAs
      Sunil Tomar, Elizabeth E. Zumbrun, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 369-379; DOI: https://doi.org/10.1124/jpet.114.220368

  3. Narumiya, Shuh

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

  4. Nicholls, David J.

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  5. Niphakis, Micah

    1. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

  6. Nunes, Kenia Pedrosa

    1. Beneficial Effect of the Soluble Guanylyl Cyclase Stimulator BAY 41-2272 on Impaired Penile Erection in db/db−/− Type II Diabetic and Obese Mice
      Kenia Pedrosa Nunes, Cleber E. Teixeira, Fernanda B. M. Priviero, Haroldo A. Toque and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 330-339; DOI: https://doi.org/10.1124/jpet.114.220970

O

  1. Oh, Luke

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  2. Okerberg, Carlin

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

P

  1. Park, Frank

    1. Activators of G Protein Signaling in the Kidney
      Frank Park
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 235-245; DOI: https://doi.org/10.1124/jpet.115.222695

  2. Perrin, Marilyn H.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  3. Pfeifer, Nathan D.

    1. Species Differences in Hepatobiliary Disposition of Taurocholic Acid in Human and Rat Sandwich-Cultured Hepatocytes: Implications for Drug-Induced Liver Injury
      Kyunghee Yang, Nathan D. Pfeifer, Kathleen Köck and Kim L. R. Brouwer
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 415-423; DOI: https://doi.org/10.1124/jpet.114.221564

  4. Phillips, Caroline

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  5. Priviero, Fernanda B. M.

    1. Beneficial Effect of the Soluble Guanylyl Cyclase Stimulator BAY 41-2272 on Impaired Penile Erection in db/db−/− Type II Diabetic and Obese Mice
      Kenia Pedrosa Nunes, Cleber E. Teixeira, Fernanda B. M. Priviero, Haroldo A. Toque and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 330-339; DOI: https://doi.org/10.1124/jpet.114.220970

  6. Pruess, Timothy H.

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

R

  1. Ramírez de Molina, Ana

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  2. Reglero, Guillermo

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  3. Rivier, Jean E.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  4. Rodrigues, A. David

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  5. Römermann, K.

    1. Pilocarpine-Induced Convulsive Activity Is Limited by Multidrug Transporters at the Rodent Blood-Brain Barrier
      K. Römermann, J. P. Bankstahl, W. Löscher and M. Bankstahl
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 351-359; DOI: https://doi.org/10.1124/jpet.114.221952

  6. Ruggeri, Roger

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

S

  1. Sakai, Yoshiki

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

  2. Salituro, Francesco G.

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  3. Sánchez, Jenifer

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  4. Sánchez-Martínez, Ruth

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  5. Sawchenko, Paul E.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  6. Schießl, Ina Maria

    1. In Vivo Visualization of the Antialbuminuric Effects of the Angiotensin-Converting Enzyme Inhibitor Enalapril
      Ina Maria Schießl, Veronika Kattler and Hayo Castrop
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 299-306; DOI: https://doi.org/10.1124/jpet.114.222125

  7. Seillier, Alexandre

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836

  8. Sexton, Patrick M.

    1. Endogenous Allosteric Modulators of G Protein–Coupled Receptors
      Emma T. van der Westhuizen, Celine Valant, Patrick M. Sexton and Arthur Christopoulos
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 246-260; DOI: https://doi.org/10.1124/jpet.114.221606

  9. Shen, Hong

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  10. Shlyakhter, Dina

    1. VX-509 (Decernotinib) Is a Potent and Selective Janus Kinase 3 Inhibitor That Attenuates Inflammation in Animal Models of Autoimmune Disease
      Sudipta Mahajan, James K. Hogan, Dina Shlyakhter, Luke Oh, Francesco G. Salituro, Luc Farmer and Thomas C. Hoock
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 405-414; DOI: https://doi.org/10.1124/jpet.114.221176

  11. Skoura, Athanasia

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  12. Su, Chunyan

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  13. Su, Hong

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  14. Sun, Dexue

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

T

  1. Takahata, Osamu

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

  2. Tan, Laura A.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

  3. Teixeira, Cleber E.

    1. Beneficial Effect of the Soluble Guanylyl Cyclase Stimulator BAY 41-2272 on Impaired Penile Erection in db/db−/− Type II Diabetic and Obese Mice
      Kenia Pedrosa Nunes, Cleber E. Teixeira, Fernanda B. M. Priviero, Haroldo A. Toque and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 330-339; DOI: https://doi.org/10.1124/jpet.114.220970

  4. Thorpe, Jessica E.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  5. Tomar, Sunil

    1. Protective Role of Cannabinoid Receptor 2 Activation in Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure through Regulation of Macrophage Polarization and MicroRNAs
      Sunil Tomar, Elizabeth E. Zumbrun, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 369-379; DOI: https://doi.org/10.1124/jpet.114.220368

  6. Tomás-Barberán, Francisco A.

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  7. Toque, Haroldo A.

    1. Beneficial Effect of the Soluble Guanylyl Cyclase Stimulator BAY 41-2272 on Impaired Penile Erection in db/db−/− Type II Diabetic and Obese Mice
      Kenia Pedrosa Nunes, Cleber E. Teixeira, Fernanda B. M. Priviero, Haroldo A. Toque and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 330-339; DOI: https://doi.org/10.1124/jpet.114.220970

U

  1. Ushikubi, Fumitaka

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

V

  1. Vadvalkar, Shraddha S.

    1. A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer
      Anja Bastian, Jessica E. Thorpe, Bryan C. Disch, Lora C. Bailey-Downs, Aleem Gangjee, Ravi K. V. Devambatla, Jim Henthorn, Kenneth M. Humphries, Shraddha S. Vadvalkar and Michael A. Ihnat
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 392-404; DOI: https://doi.org/10.1124/jpet.114.220335

  2. Valant, Celine

    1. Endogenous Allosteric Modulators of G Protein–Coupled Receptors
      Emma T. van der Westhuizen, Celine Valant, Patrick M. Sexton and Arthur Christopoulos
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 246-260; DOI: https://doi.org/10.1124/jpet.114.221606

  3. van der Westhuizen, Emma T.

    1. Endogenous Allosteric Modulators of G Protein–Coupled Receptors
      Emma T. van der Westhuizen, Celine Valant, Patrick M. Sexton and Arthur Christopoulos
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 246-260; DOI: https://doi.org/10.1124/jpet.114.221606

  4. Vanegas, Fabiola

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

  5. Vargas, Teodoro

    1. The Ellagic Acid Derivative 4,4′-Di-O-Methylellagic Acid Efficiently Inhibits Colon Cancer Cell Growth through a Mechanism Involving WNT16
      Ana Ramírez de Molina, Teodoro Vargas, Susana Molina, Jenifer Sánchez, Jorge Martínez-Romero, Margarita González-Vallinas, Roberto Martín-Hernández, Ruth Sánchez-Martínez, Marta Gómez de Cedrón, Alberto Dávalos, Luca Calani, Daniele Del Rio, Antonio González-Sarrías, Juan Carlos Espín, Francisco A. Tomás-Barberán and Guillermo Reglero
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 433-444; DOI: https://doi.org/10.1124/jpet.114.221796

  6. Vaughan, Joan M.

    1. Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies
      Marilyn H. Perrin, Laura A. Tan, Joan M. Vaughan, Kathy A. Lewis, Cynthia J. Donaldson, Charleen Miller, Judit Erchegyi, Jean E. Rivier and Paul E. Sawchenko
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 307-317; DOI: https://doi.org/10.1124/jpet.114.222307

W

  1. Ward, Jessica

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  2. Warner, Roscoe

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  3. Webb, R. Clinton

    1. Beneficial Effect of the Soluble Guanylyl Cyclase Stimulator BAY 41-2272 on Impaired Penile Erection in db/db−/− Type II Diabetic and Obese Mice
      Kenia Pedrosa Nunes, Cleber E. Teixeira, Fernanda B. M. Priviero, Haroldo A. Toque and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 330-339; DOI: https://doi.org/10.1124/jpet.114.220970

  4. White, H. Steve

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

  5. Wilcox, Karen S.

    1. Evaluating an Etiologically Relevant Platform for Therapy Development for Temporal Lobe Epilepsy: Effects of Carbamazepine and Valproic Acid on Acute Seizures and Chronic Behavioral Comorbidities in the Theiler’s Murine Encephalomyelitis Virus Mouse Model
      Melissa L. Barker-Haliski, E. Jill Dahle, Taylor D. Heck, Timothy H. Pruess, Fabiola Vanegas, Karen S. Wilcox and H. Steve White
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 318-329; DOI: https://doi.org/10.1124/jpet.114.222513

  6. Wiley, Jenny L.

    1. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

  7. Wiley, Katherine

    1. Pharmacological Characterization of AZD5069, a Slowly Reversible CXC Chemokine Receptor 2 Antagonist
      David J. Nicholls, Katherine Wiley, Ian Dainty, Fraser MacIntosh, Caroline Phillips, Alasdair Gaw and Carina Kärrman Mårdh
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 340-350; DOI: https://doi.org/10.1124/jpet.114.221358

  8. Wilkerson, Jenny L.

    1. Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice
      Bogna Ignatowska-Jankowska, Jenny L. Wilkerson, Mohammed Mustafa, Rehab Abdullah, Micah Niphakis, Jenny L. Wiley, Benjamin F. Cravatt and Aron H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 424-432; DOI: https://doi.org/10.1124/jpet.114.222315

Y

  1. Yang, Kyunghee

    1. Species Differences in Hepatobiliary Disposition of Taurocholic Acid in Human and Rat Sandwich-Cultured Hepatocytes: Implications for Drug-Induced Liver Injury
      Kyunghee Yang, Nathan D. Pfeifer, Kathleen Köck and Kim L. R. Brouwer
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 415-423; DOI: https://doi.org/10.1124/jpet.114.221564

  2. Yao, Ming

    1. Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys
      Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, Lun Li, R. Marcus Fancher, Ramaswamy Iyer, Punit Marathe, Yurong Lai and A. David Rodrigues
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 380-391; DOI: https://doi.org/10.1124/jpet.114.221804

  3. Yuhki, Koh-ichi

    1. The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Osamu Takahata, Yoshiki Sakai, Shuh Narumiya and Fumitaka Ushikubi
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 269-278; DOI: https://doi.org/10.1124/jpet.115.222612

Z

  1. Zaki, Armia

    1. Simultaneous Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Shares Discriminative Stimulus Effects with Δ9-Tetrahydrocannabinol in Mice
      Lenka Hruba, Alexandre Seillier, Armia Zaki, Benjamin F. Cravatt, Aron H. Lichtman, Andrea Giuffrida and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 261-268; DOI: https://doi.org/10.1124/jpet.115.222836

  2. Zhang, Yanwei

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788

  3. Zheng, Wei

    1. PF-1355, a Mechanism-Based Myeloperoxidase Inhibitor, Prevents Immune Complex Vasculitis and Anti–Glomerular Basement Membrane Glomerulonephritis
      Wei Zheng, Roscoe Warner, Roger Ruggeri, Chunyan Su, Christian Cortes, Athanasia Skoura, Jessica Ward, Kay Ahn, Amit Kalgutkar, Dexue Sun, Tristan S. Maurer, Paul D. Bonin, Carlin Okerberg, Walter Bobrowski, Thomas Kawabe, Yanwei Zhang, Timothy Coskran, Sammy Bell, Bhupesh Kapoor, Kent Johnson and Leonard Buckbinder
      Journal of Pharmacology and Experimental Therapeutics May 2015, 353 (2) 288-298; DOI: https://doi.org/10.1124/jpet.114.221788
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