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Research ArticleDrug Discovery and Translational Medicine

Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism

Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

Article Information

vol. 353 no. 1 132-149
DOI 
https://doi.org/10.1124/jpet.114.218560
PubMed 
25650377
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 4, 2014
  • Accepted January 30, 2015
  • Published online February 27, 2015.

Article Versions

Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Daniel J. Wendt,
  2. Melita Dvorak-Ewell1,
  3. Sherry Bullens,
  4. Florence Lorget2,
  5. Sean M. Bell,
  6. Jeff Peng,
  7. Sianna Castillo,
  8. Mika Aoyagi-Scharber,
  9. Charles A. O’Neill,
  10. Pavel Krejci3,
  11. William R. Wilcox4,
  12. David L. Rimoin, and
  13. Stuart Bunting
  1. BioMarin Pharmaceutical Inc., Novato, California (D.J.W., M.D.-E., Sh.B., F.L., S.M.B., J.P., S.C., M.A.-S., C.A.O., St.B.); and Cedars-Sinai Medical Center, Los Angeles, California (P.K., W.R.W., D.L.R.)
  1. Address correspondence to:
    Daniel J. Wendt, Department of Analytical Chemistry, BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA 94949. E-mail: dwendt{at}bmrn.com
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Research ArticleDrug Discovery and Translational Medicine

C-Type Natriuretic Peptide Variant for FGFR3-Related Dwarfism

Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
Journal of Pharmacology and Experimental Therapeutics April 1, 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560
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