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Index by author

April 01, 2015; Volume 353,Issue 1

A

  1. Adams, Sean H.

    1. Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
      Daniel H. Bedinger, Ira D. Goldfine, John A. Corbin, Marina K. Roell and Sean H. Adams
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 35-43; DOI: https://doi.org/10.1124/jpet.114.221309

  2. Aguayo, Luis G.

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

  3. Akaogi, Ryo

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  4. Aoyagi-Scharber, Mika

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  5. Ason, Brandon

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

B

  1. Babu, Ellappan

    1. Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
      Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523

  2. Bedinger, Daniel H.

    1. Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
      Daniel H. Bedinger, Ira D. Goldfine, John A. Corbin, Marina K. Roell and Sean H. Adams
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 35-43; DOI: https://doi.org/10.1124/jpet.114.221309

  3. Bell, Sean M.

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  4. Benavidez, Jillian M.

    1. Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
      Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

  5. Berg, Kelly A.

    1. Dual Regulation of δ-Opioid Receptor Function by Arachidonic Acid Metabolites in Rat Peripheral Sensory Neurons
      Laura C. Sullivan, Kelly A. Berg and William P. Clarke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 44-51; DOI: https://doi.org/10.1124/jpet.114.221366

  6. Bhutia, Yangzom D.

    1. Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
      Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523

  7. Bivin, William

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  8. Black, Mendy

    1. Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
      Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

  9. Blednov, Yuri A.

    1. Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
      Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

  10. Borroni, Edilio

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  11. Bruns, Andreas

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  12. Bullens, Sherry

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  13. Bunting, Stuart

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  14. Burgos, Carlos F.

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

C

  1. Carter, Dwayne E.

    1. Aryl Hydrocarbon Receptor–Dependent Stanniocalcin 2 Induction by Cinnabarinic Acid Provides Cytoprotection against Endoplasmic Reticulum and Oxidative Stress
      Aditya D. Joshi, Dwayne E. Carter, Tod A. Harper and Cornelis J. Elferink
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 201-212; DOI: https://doi.org/10.1124/jpet.114.222265

  2. Castillo, Sianna

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  3. Causey, Corey P.

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  4. Chan, Joyce C. Y.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  5. Chang, Yan

    1. Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
      Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665

  6. Chen, Jingyu

    1. Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
      Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665

  7. Christopoulos, Arthur

    1. Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
      Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913

  8. Clarke, William P.

    1. Dual Regulation of δ-Opioid Receptor Function by Arachidonic Acid Metabolites in Rat Peripheral Sensory Neurons
      Laura C. Sullivan, Kelly A. Berg and William P. Clarke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 44-51; DOI: https://doi.org/10.1124/jpet.114.221366

  9. Corbin, John A.

    1. Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
      Daniel H. Bedinger, Ira D. Goldfine, John A. Corbin, Marina K. Roell and Sean H. Adams
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 35-43; DOI: https://doi.org/10.1124/jpet.114.221309

  10. Couraud, Pierre-Olivier

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  11. Cui, Xiangli

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  12. Cui, Ying-Yu

    1. Pine Bark Extracts: Nutraceutical, Pharmacological, and Toxicological Evaluation
      Ying-Ya Li, Jiao Feng, Xiao-Lu Zhang and Ying-Yu Cui
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 9-16; DOI: https://doi.org/10.1124/jpet.114.220277

D

  1. Durham, Nickie

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

  2. Duthaler, Urs

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

  3. Dvorak-Ewell, Melita

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

E

  1. Elferink, Cornelis J.

    1. Aryl Hydrocarbon Receptor–Dependent Stanniocalcin 2 Induction by Cinnabarinic Acid Provides Cytoprotection against Endoplasmic Reticulum and Oxidative Stress
      Aditya D. Joshi, Dwayne E. Carter, Tod A. Harper and Cornelis J. Elferink
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 201-212; DOI: https://doi.org/10.1124/jpet.114.222265

  2. Even, Sarah

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

F

  1. Feng, Jiao

    1. Pine Bark Extracts: Nutraceutical, Pharmacological, and Toxicological Evaluation
      Ying-Ya Li, Jiao Feng, Xiao-Lu Zhang and Ying-Yu Cui
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 9-16; DOI: https://doi.org/10.1124/jpet.114.220277

  2. Fujimoto, Kazuhisa

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  3. Fukasawa, Masayoshi

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  4. Funk, Christoph

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

G

  1. Ganapathy, Vadivel

    1. Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
      Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523

  2. Gavin, Terrence

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  3. Geohagen, Brian C.

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  4. Gloge, Andreas

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  5. Goldfine, Ira D.

    1. Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
      Daniel H. Bedinger, Ira D. Goldfine, John A. Corbin, Marina K. Roell and Sean H. Adams
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 35-43; DOI: https://doi.org/10.1124/jpet.114.221309

  6. Gopal, Elangovan

    1. Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
      Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523

  7. Grouzmann, Eric

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

H

  1. Harper, Tod A.

    1. Aryl Hydrocarbon Receptor–Dependent Stanniocalcin 2 Induction by Cinnabarinic Acid Provides Cytoprotection against Endoplasmic Reticulum and Oxidative Stress
      Aditya D. Joshi, Dwayne E. Carter, Tod A. Harper and Cornelis J. Elferink
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 201-212; DOI: https://doi.org/10.1124/jpet.114.222265

  2. Harris, R. Adron

    1. Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
      Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

  3. Harrison, Anthony C.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  4. Hartman, James J.

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

  5. Hartung, Thomas

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  6. Harvey, Robert J.

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

  7. Henne, Kirk R.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  8. Higbee, Jared

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  9. Hofseth, Anne B.

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  10. Hofseth, Lorne J.

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  11. Honer, Michael

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  12. Hosoya, Ken-ichi

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  13. Howard, Monique

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  14. Hwee, Darren T.

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

  15. Hysek, Cédric M.

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

I

  1. Iida, Manami

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  2. Ishibashi, Megumi

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  3. Ishii-Watabe, Akiko

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

J

  1. Jackson, Simon M.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  2. Jaeschke, Georg

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  3. Jasper, Jeffrey R.

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

  4. Joshi, Aditya D.

    1. Aryl Hydrocarbon Receptor–Dependent Stanniocalcin 2 Induction by Cinnabarinic Acid Provides Cytoprotection against Endoplasmic Reticulum and Oxidative Stress
      Aditya D. Joshi, Dwayne E. Carter, Tod A. Harper and Cornelis J. Elferink
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 201-212; DOI: https://doi.org/10.1124/jpet.114.222265

K

  1. Kaneko, Yosuke

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  2. Kennedy, Adam R.

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

  3. Ketchem, Randal R.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  4. Kilduff, Thomas S.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  5. King, Chadwick

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  6. Kolczewski, Sabine

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  7. Kondoh, Masuo

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  8. Koole, Cassandra

    1. Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
      Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913

  9. Kosharskyy, Boleslav

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  10. Krejci, Pavel

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  11. Kuennecke, Basil

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

L

  1. Leiter, Courtney R.

    1. Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
      Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

  2. Li, Ying-Ya

    1. Pine Bark Extracts: Nutraceutical, Pharmacological, and Toxicological Evaluation
      Ying-Ya Li, Jiao Feng, Xiao-Lu Zhang and Ying-Yu Cui
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 9-16; DOI: https://doi.org/10.1124/jpet.114.220277

  3. Liechti, Matthias E.

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

  4. Lindemann, Lothar

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  5. Liu, Kangkang

    1. Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
      Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665

  6. Liu, Qiang

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  7. LoPachin, Richard M.

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  8. Lorget, Florence

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

M

  1. Makwana, Raj

    1. The Effect of Phytocannabinoids on Airway Hyper-Responsiveness, Airway Inflammation, and Cough
      Raj Makwana, Radhakrishnan Venkatasamy, Domenico Spina and Clive Page
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 169-180; DOI: https://doi.org/10.1124/jpet.114.221283

  2. Malik, Fady I.

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

  3. Matsuda, Katherine C.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  4. Michaels, Mark Leo

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  5. Miller, Laurence J.

    1. Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
      Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913

  6. Montezano, Augusto C.

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

  7. Moraga-Cid, Gustavo

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

  8. Morairty, Stephen R.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  9. Moreau, Jean-Luc

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

N

  1. Nagase, Shotaro

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  2. Neves, Karla B.

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

  3. Nguyen Dinh Cat, Aurelie

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

  4. Niederhauser, Urs

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

O

  1. O’Neill, Charles A.

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  2. Ohtsuki, Sumio

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  3. Osterndorff-Kahanek, Elizabeth

    1. Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
      Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

P

  1. Paehler, Axel

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  2. Page, Clive

    1. The Effect of Phytocannabinoids on Airway Hyper-Responsiveness, Airway Inflammation, and Cough
      Raj Makwana, Radhakrishnan Venkatasamy, Domenico Spina and Clive Page
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 169-180; DOI: https://doi.org/10.1124/jpet.114.221283

  3. Palacios, Roberto

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

  4. Parrott, Neil J.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  5. Peng, Jeff

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  6. Piper, Derek E.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  7. Polonchuk, Liudmila

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  8. Porter, Richard H.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  9. Prasad, Puttur D.

    1. Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
      Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523

  10. Prinssen, Eric

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

R

  1. Ramachandran, Sabarish

    1. Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
      Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523

  2. Retter, Marc W.

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  3. Rickli, Anna

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

  4. Rigas, Basil

    1. The Evolving Role of Nonsteroidal Anti-Inflammatory Drugs in Colon Cancer Prevention: A Cause for Optimism
      Basil Rigas and George J. Tsioulias
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 2-8; DOI: https://doi.org/10.1124/jpet.114.220806

  5. Rimoin, David L.

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  6. Rios, Francisco J.

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

  7. Roell, Marina K.

    1. Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
      Daniel H. Bedinger, Ira D. Goldfine, John A. Corbin, Marina K. Roell and Sean H. Adams
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 35-43; DOI: https://doi.org/10.1124/jpet.114.221309

  8. Ryans, Julie

    1. The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
      Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224

S

  1. Sánchez, Andrea

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

  2. San Martin, Loreto

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

  3. Schaffner, Antonia

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

  4. Scharf, Sebastian H.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  5. Schmid, Yasmin

    1. Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
      Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356

  6. Schneider, Manfred

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  7. Sexton, Patrick M.

    1. Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
      Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913

  8. Shaparin, Naum

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  9. Shirasago, Yoshitaka

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  10. Simms, John

    1. Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
      Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913

  11. Smothers, C. Thetford

    1. Cysteine Substitution of Transmembrane Domain Amino Acids Alters the Ethanol Inhibition of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
      Minfu Xu, C. Thetford Smothers and John J. Woodward
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 91-101; DOI: https://doi.org/10.1124/jpet.114.222034

  12. Spina, Domenico

    1. The Effect of Phytocannabinoids on Airway Hyper-Responsiveness, Airway Inflammation, and Cough
      Raj Makwana, Radhakrishnan Venkatasamy, Domenico Spina and Clive Page
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 169-180; DOI: https://doi.org/10.1124/jpet.114.221283

  13. Spooren, Will

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  14. Subramanian, Venkataraman

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  15. Sullivan, Laura C.

    1. Dual Regulation of δ-Opioid Receptor Function by Arachidonic Acid Metabolites in Rat Peripheral Sensory Neurons
      Laura C. Sullivan, Kelly A. Berg and William P. Clarke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 44-51; DOI: https://doi.org/10.1124/jpet.114.221366

  16. Sun, Jeonghoon

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

T

  1. Tachikawa, Masanori

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  2. Tada, Minoru

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  3. Tang, Jie

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  4. Terasaki, Tetsuya

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

  5. Thompson, Paul R.

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  6. Touyz, Rhian M.

    1. Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
      Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002

  7. Tsioulias, George J.

    1. The Evolving Role of Nonsteroidal Anti-Inflammatory Drugs in Colon Cancer Prevention: A Cause for Optimism
      Basil Rigas and George J. Tsioulias
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 2-8; DOI: https://doi.org/10.1124/jpet.114.220806

U

  1. Uchida, Yasuo

    1. Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
      Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

V

  1. Venkatasamy, Radhakrishnan

    1. The Effect of Phytocannabinoids on Airway Hyper-Responsiveness, Airway Inflammation, and Cough
      Raj Makwana, Radhakrishnan Venkatasamy, Domenico Spina and Clive Page
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 169-180; DOI: https://doi.org/10.1124/jpet.114.221283

  2. Vieira, Eric

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  3. von Kienlin, Markus

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  4. Vydyanathan, Amaresh

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

W

  1. Wang, Qingtong

    1. Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
      Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665

  2. Wang, Wei

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

  3. Watari, Akihiro

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  4. Wei, Wei

    1. Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
      Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665

  5. Wendt, Daniel J.

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  6. Wettstein, Joseph G.

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  7. Wichmann, Juergen

    1. Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
      Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

  8. Wilcox, William R.

    1. Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
      Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560

  9. Witalison, Erin E.

    1. Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
      Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

  10. Woodward, John J.

    1. Cysteine Substitution of Transmembrane Domain Amino Acids Alters the Ethanol Inhibition of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
      Minfu Xu, C. Thetford Smothers and John J. Woodward
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 91-101; DOI: https://doi.org/10.1124/jpet.114.222034

  11. Wootten, Denise

    1. Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
      Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913

  12. Wu, Huaxun

    1. Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
      Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665

X

  1. Xu, Minfu

    1. Cysteine Substitution of Transmembrane Domain Amino Acids Alters the Ethanol Inhibition of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
      Minfu Xu, C. Thetford Smothers and John J. Woodward
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 91-101; DOI: https://doi.org/10.1124/jpet.114.222034

  2. Xu, Ren

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242

Y

  1. Yagi, Kiyohito

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  2. Yamashita, Mayo

    1. Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
      Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653

  3. Yévenes, Gonzalo E.

    1. Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
      Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143

Z

  1. Zhang, Lihai

    1. 2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
      Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622

  2. Zhang, Xiao-Lu

    1. Pine Bark Extracts: Nutraceutical, Pharmacological, and Toxicological Evaluation
      Ying-Ya Li, Jiao Feng, Xiao-Lu Zhang and Ying-Yu Cui
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 9-16; DOI: https://doi.org/10.1124/jpet.114.220277

  3. Zhou, Lei

    1. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
      Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
      Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242
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