Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

April 01, 2015; Volume 353,Issue 1

Highlighted Papers

  • You have access
    Differential Pathway Coupling Drives Selectivity of an Insulin Receptor Agonist
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0415HI
  • You have access
    A Fast Skeletal Troponin Activator Improves Exercise Tolerance in Heart Failure
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0415HIa
  • You have access
    Interaction between Bupropion and MDMA
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0415HIb
  • You have access
    Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 1; DOI: https://doi.org/10.1124/jpet.115.0415HIc

Minireviews

  • You have access
    The Evolving Role of Nonsteroidal Anti-Inflammatory Drugs in Colon Cancer Prevention: A Cause for Optimism
    Basil Rigas and George J. Tsioulias
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 2-8; DOI: https://doi.org/10.1124/jpet.114.220806
  • You have access
    Pine Bark Extracts: Nutraceutical, Pharmacological, and Toxicological Evaluation
    Ying-Ya Li, Jiao Feng, Xiao-Lu Zhang and Ying-Yu Cui
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 9-16; DOI: https://doi.org/10.1124/jpet.114.220277

Behavioral Pharmacology

  • You have access
    Interactions between Bupropion and 3,4-Methylenedioxymethamphetamine in Healthy Subjects
    Yasmin Schmid, Anna Rickli, Antonia Schaffner, Urs Duthaler, Eric Grouzmann, Cédric M. Hysek and Matthias E. Liechti
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 102-111; DOI: https://doi.org/10.1124/jpet.114.222356
  • You have access
    Glycine Receptors Containing α2 or α3 Subunits Regulate Specific Ethanol-Mediated Behaviors
    Yuri A. Blednov, Jillian M. Benavidez, Mendy Black, Courtney R. Leiter, Elizabeth Osterndorff-Kahanek and R. Adron Harris
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 181-191; DOI: https://doi.org/10.1124/jpet.114.221895

Cellular and Molecular

  • You have access
    Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates
    Elangovan Gopal, Ellappan Babu, Sabarish Ramachandran, Yangzom D. Bhutia, Puttur D. Prasad and Vadivel Ganapathy
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 17-26; DOI: https://doi.org/10.1124/jpet.114.221523
  • You have access
    Cholesteryl Ester-Transfer Protein Inhibitors Stimulate Aldosterone Biosynthesis in Adipocytes through Nox-Dependent Processes
    Francisco J. Rios, Karla B. Neves, Aurelie Nguyen Dinh Cat, Sarah Even, Roberto Palacios, Augusto C. Montezano and Rhian M. Touyz
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 27-34; DOI: https://doi.org/10.1124/jpet.114.221002
  • You have access
    Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
    Daniel H. Bedinger, Ira D. Goldfine, John A. Corbin, Marina K. Roell and Sean H. Adams
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 35-43; DOI: https://doi.org/10.1124/jpet.114.221309
  • You have access
    Dual Regulation of δ-Opioid Receptor Function by Arachidonic Acid Metabolites in Rat Peripheral Sensory Neurons
    Laura C. Sullivan, Kelly A. Berg and William P. Clarke
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 44-51; DOI: https://doi.org/10.1124/jpet.114.221366
  • You have access
    Aryl Hydrocarbon Receptor–Dependent Stanniocalcin 2 Induction by Cinnabarinic Acid Provides Cytoprotection against Endoplasmic Reticulum and Oxidative Stress
    Aditya D. Joshi, Dwayne E. Carter, Tod A. Harper and Cornelis J. Elferink
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 201-212; DOI: https://doi.org/10.1124/jpet.114.222265

Drug Discovery and Translational Medicine

  • You have access
    Differential Impact of Amino Acid Substitutions on Critical Residues of the Human Glucagon-Like Peptide-1 Receptor Involved in Peptide Activity and Small-Molecule Allostery
    Cassandra Koole, Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos and Patrick M. Sexton
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 52-63; DOI: https://doi.org/10.1124/jpet.114.220913
  • You have access
    Discovery of Anti–Claudin-1 Antibodies as Candidate Therapeutics against Hepatitis C Virus
    Mayo Yamashita, Manami Iida, Minoru Tada, Yoshitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi and Masuo Kondoh
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 112-118; DOI: https://doi.org/10.1124/jpet.114.217653
  • You have access
    Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity–Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor–Binding Enhancement
    Kirk R. Henne, Brandon Ason, Monique Howard, Wei Wang, Jeonghoon Sun, Jared Higbee, Jie Tang, Katherine C. Matsuda, Ren Xu, Lei Zhou, Joyce C. Y. Chan, Chadwick King, Derek E. Piper, Randal R. Ketchem, Mark Leo Michaels, Simon M. Jackson and Marc W. Retter
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 119-131; DOI: https://doi.org/10.1124/jpet.114.221242
  • You have access
    Neutral Endopeptidase-Resistant C-Type Natriuretic Peptide Variant Represents a New Therapeutic Approach for Treatment of Fibroblast Growth Factor Receptor 3–Related Dwarfism
    Daniel J. Wendt, Melita Dvorak-Ewell, Sherry Bullens, Florence Lorget, Sean M. Bell, Jeff Peng, Sianna Castillo, Mika Aoyagi-Scharber, Charles A. O’Neill, Pavel Krejci, William R. Wilcox, David L. Rimoin and Stuart Bunting
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 132-149; DOI: https://doi.org/10.1124/jpet.114.218560
  • You have access
    2-Acetylcyclopentanone, an Enolate-Forming 1,3-Dicarbonyl Compound, Is Cytoprotective in Warm Ischemia-Reperfusion Injury of Rat Liver
    Boleslav Kosharskyy, Amaresh Vydyanathan, Lihai Zhang, Naum Shaparin, Brian C. Geohagen, William Bivin, Qiang Liu, Terrence Gavin and Richard M. LoPachin
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 150-158; DOI: https://doi.org/10.1124/jpet.114.221622
  • You have access
    The Small-Molecule Fast Skeletal Troponin Activator, CK-2127107, Improves Exercise Tolerance in a Rat Model of Heart Failure
    Darren T. Hwee, Adam R. Kennedy, James J. Hartman, Julie Ryans, Nickie Durham, Fady I. Malik and Jeffrey R. Jasper
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 159-168; DOI: https://doi.org/10.1124/jpet.114.222224
  • You have access
    Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression
    Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony C. Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil J. Parrott, Liudmila Polonchuk, Urs Niederhauser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Hartung, Michael Honer, Edilio Borroni, Jean-Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein and Georg Jaeschke
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 213-233; DOI: https://doi.org/10.1124/jpet.114.222463

Gastrointestinal, Hepatic, Pulmonary, and Renal

  • You have access
    Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences
    Erin E. Witalison, Xiangli Cui, Anne B. Hofseth, Venkataraman Subramanian, Corey P. Causey, Paul R. Thompson and Lorne J. Hofseth
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 64-70; DOI: https://doi.org/10.1124/jpet.115.222745

Inflammation, Immunopharmacology, and Asthma

  • You have access
    Ginsenoside Metabolite Compound K Suppresses T-Cell Priming via Modulation of Dendritic Cell Trafficking and Costimulatory Signals, Resulting in Alleviation of Collagen-Induced Arthritis
    Jingyu Chen, Huaxun Wu, Qingtong Wang, Yan Chang, Kangkang Liu and Wei Wei
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 71-79; DOI: https://doi.org/10.1124/jpet.114.220665
  • You have access
    The Effect of Phytocannabinoids on Airway Hyper-Responsiveness, Airway Inflammation, and Cough
    Raj Makwana, Radhakrishnan Venkatasamy, Domenico Spina and Clive Page
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 169-180; DOI: https://doi.org/10.1124/jpet.114.221283

Metabolism, Transport, and Pharmacogenomics

  • You have access
    Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells
    Yosuke Kaneko, Masanori Tachikawa, Ryo Akaogi, Kazuhisa Fujimoto, Megumi Ishibashi, Yasuo Uchida, Pierre-Olivier Couraud, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 192-200; DOI: https://doi.org/10.1124/jpet.114.220210

Neuropharmacology

  • You have access
    Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain
    Andrea Sánchez, Gonzalo E. Yévenes, Loreto San Martin, Carlos F. Burgos, Gustavo Moraga-Cid, Robert J. Harvey and Luis G. Aguayo
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 80-90; DOI: https://doi.org/10.1124/jpet.114.221143
  • You have access
    Cysteine Substitution of Transmembrane Domain Amino Acids Alters the Ethanol Inhibition of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
    Minfu Xu, C. Thetford Smothers and John J. Woodward
    Journal of Pharmacology and Experimental Therapeutics April 2015, 353 (1) 91-101; DOI: https://doi.org/10.1124/jpet.114.222034
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 353 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 353, Issue 1
1 Apr 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Highlighted Papers
  • Minireviews
  • Behavioral Pharmacology
  • Cellular and Molecular
  • Drug Discovery and Translational Medicine
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Inflammation, Immunopharmacology, and Asthma
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
  • Most Cited
  • Most Read
Loading
  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics