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Index by author

March 01, 2015; Volume 352,Issue 3

A

  1. Adolf, Günther R.

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  2. Ainslie, Garrett R.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

  3. Albrecht, Christoph

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  4. Amari, Gabriele

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  5. Amin, Shantu

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  6. Armani, Elisabetta

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  7. Aufderheide, Tom P.

    1. Thrombopoietin Receptor Agonists Protect Human Cardiac Myocytes from Injury by Activation of Cell Survival Pathways
      John E. Baker, Jidong Su, Stacy Koprowski, Anuradha Dhanasekaran, Tom P. Aufderheide and Garrett J. Gross
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 429-437; DOI: https://doi.org/10.1124/jpet.114.221747

B

  1. Bagnacani, Valentina

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  2. Baker, John E.

    1. Thrombopoietin Receptor Agonists Protect Human Cardiac Myocytes from Injury by Activation of Cell Survival Pathways
      John E. Baker, Jidong Su, Stacy Koprowski, Anuradha Dhanasekaran, Tom P. Aufderheide and Garrett J. Gross
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 429-437; DOI: https://doi.org/10.1124/jpet.114.221747

  3. Bassani, Franco

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  4. Battipaglia, Loredana

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  5. Bergamaschi, Marco

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  6. Bertacche, Vittorio

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  7. Bhattacharya, Sayak

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

  8. Blaukopf, Claudia

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  9. Bolzoni, Pier Tonino

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  10. Bonaventure, Pascal

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  11. Bosco, Raffaella

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  12. Brust, Tarsis F.

    1. Bias Analyses of Preclinical and Clinical D2 Dopamine Ligands: Studies with Immediate and Complex Signaling Pathways
      Tarsis F. Brust, Michael P. Hayes, David L. Roman, Kevin D. Burris and Val J. Watts
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 480-493; DOI: https://doi.org/10.1124/jpet.114.220293

  13. Buccellati, Carola

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  14. Burris, Kevin D.

    1. Bias Analyses of Preclinical and Clinical D2 Dopamine Ligands: Studies with Immediate and Complex Signaling Pathways
      Tarsis F. Brust, Michael P. Hayes, David L. Roman, Kevin D. Burris and Val J. Watts
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 480-493; DOI: https://doi.org/10.1124/jpet.114.220293

C

  1. Cai, Hao

    1. Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
      Tianxiang (Kevin) Han, William R. Proctor, Chester L. Costales, Hao Cai, Ruth S. Everett and Dhiren R. Thakker
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 519-528; DOI: https://doi.org/10.1124/jpet.114.220350

  2. Canning, Brendan J.

    1. Effect of Memantine on Cough Reflex Sensitivity: Translational Studies in Guinea Pigs and Humans
      Peter V. Dicpinigaitis, Brendan J. Canning, Rachel Garner and Blake Paterson
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 448-454; DOI: https://doi.org/10.1124/jpet.114.221218

  3. Capaldi, Carmelida

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  4. Carnini, Chiara

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558
    2. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  5. Carruthers, Nicholas

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  6. Caruso, Paola

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558
    2. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  7. Carzaniga, Laura

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  8. Catinella, Silvia

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  9. Cenacchi, Valentina

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  10. Cherrington, Nathan J.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

  11. Chun, Jaeyoung

    1. Fexofenadine Regulates Nuclear Factor-κB Signaling and Endoplasmic Reticulum Stress in Intestinal Epithelial Cells and Ameliorates Acute and Chronic Colitis in Mice
      Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jaeyoung Chun and Joo Sung Kim
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 455-461; DOI: https://doi.org/10.1124/jpet.114.217844

  12. Civelli, Maurizio

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558
    2. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  13. Clarke, John D.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

  14. Colledge, Ashley L.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  15. Costales, Chester L.

    1. Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
      Tianxiang (Kevin) Han, William R. Proctor, Chester L. Costales, Hao Cai, Ruth S. Everett and Dhiren R. Thakker
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 519-528; DOI: https://doi.org/10.1124/jpet.114.220350

D

  1. De Fanti, Renato

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  2. Delcanale, Maurizio

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  3. Dhanasekaran, Anuradha

    1. Thrombopoietin Receptor Agonists Protect Human Cardiac Myocytes from Injury by Activation of Cell Survival Pathways
      John E. Baker, Jidong Su, Stacy Koprowski, Anuradha Dhanasekaran, Tom P. Aufderheide and Garrett J. Gross
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 429-437; DOI: https://doi.org/10.1124/jpet.114.221747

  4. Dick, Taryn E.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  5. Dicpinigaitis, Peter V.

    1. Effect of Memantine on Cough Reflex Sensitivity: Translational Studies in Guinea Pigs and Humans
      Peter V. Dicpinigaitis, Brendan J. Canning, Rachel Garner and Blake Paterson
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 448-454; DOI: https://doi.org/10.1124/jpet.114.221218

  6. Dugovic, Christine

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  7. Dzierlenga, Anika L.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

E

  1. Evans, William E.

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  2. Everett, Ruth S.

    1. Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
      Tianxiang (Kevin) Han, William R. Proctor, Chester L. Costales, Hao Cai, Ruth S. Everett and Dhiren R. Thakker
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 519-528; DOI: https://doi.org/10.1124/jpet.114.220350

F

  1. Facchinetti, Fabrizio

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558
    2. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  2. Fernandez, Christian A.

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  3. Finkelman, Fred D.

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  4. Fitz, Stephanie D.

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  5. Fox, Todd E.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

G

  1. Garin-Chesa, Pilar

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  2. Garner, Rachel

    1. Effect of Memantine on Cough Reflex Sensitivity: Translational Studies in Guinea Pigs and Humans
      Peter V. Dicpinigaitis, Brendan J. Canning, Rachel Garner and Blake Paterson
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 448-454; DOI: https://doi.org/10.1124/jpet.114.221218

  3. Gaudette, Fleur

    1. Effects of β-Blockers and Tricyclic Antidepressants on the Activity of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2)
      Jennifer Lu, Veronique Michaud, Liliam Gabriela Guilarte Moya, Fleur Gaudette, Yat Hei Leung and Jacques Turgeon
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 552-558; DOI: https://doi.org/10.1124/jpet.114.219287

  4. Geiselmann, Lena

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  5. Gerlich, Daniel W.

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  6. Ghidini, Eleonora

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  7. Gorin, Fredric

    1. A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression
      Ana Cristina G. Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H. Nantz, Pamela J. Lein and Fredric Gorin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 438-447; DOI: https://doi.org/10.1124/jpet.114.220186

  8. Grider, John R.

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

  9. Grodzki, Ana Cristina G.

    1. A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression
      Ana Cristina G. Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H. Nantz, Pamela J. Lein and Fredric Gorin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 438-447; DOI: https://doi.org/10.1124/jpet.114.220186

  10. Gross, Garrett J.

    1. Thrombopoietin Receptor Agonists Protect Human Cardiac Myocytes from Injury by Activation of Cell Survival Pathways
      John E. Baker, Jidong Su, Stacy Koprowski, Anuradha Dhanasekaran, Tom P. Aufderheide and Garrett J. Gross
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 429-437; DOI: https://doi.org/10.1124/jpet.114.221747

H

  1. Han, Tianxiang (Kevin)

    1. Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
      Tianxiang (Kevin) Han, William R. Proctor, Chester L. Costales, Hao Cai, Ruth S. Everett and Dhiren R. Thakker
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 519-528; DOI: https://doi.org/10.1124/jpet.114.220350

  2. Harada, Akina

    1. In Vivo Pharmacological Characterization of TAK-063, a Potent and Selective Phosphodiesterase 10A Inhibitor with Antipsychotic-Like Activity in Rodents
      Kazunori Suzuki, Akina Harada, Eri Shiraishi and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 471-479; DOI: https://doi.org/10.1124/jpet.114.218552

  3. Hargraves, Tiffanie L.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

  4. Hayes, Michael P.

    1. Bias Analyses of Preclinical and Clinical D2 Dopamine Ligands: Studies with Immediate and Complex Signaling Pathways
      Tarsis F. Brust, Michael P. Hayes, David L. Roman, Kevin D. Burris and Val J. Watts
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 480-493; DOI: https://doi.org/10.1124/jpet.114.220293

  5. Heck, Diane E.

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  6. Heindel, Ned D.

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  7. Hengst, Jeremy A.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  8. Hirsch, Emilio

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  9. Hofmann, Marco H.

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  10. Hossain, Muhammad M.

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  11. Hu, Wenhui

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

  12. Hu, Xiaoyu

    1. Curcumin Attenuates Opioid Tolerance and Dependence by Inhibiting Ca2+/Calmodulin-Dependent Protein Kinase II α Activity
      Xiaoyu Hu, Fang Huang, Magdalena Szymusiak, Ying Liu and Zaijie Jim Wang
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 420-428; DOI: https://doi.org/10.1124/jpet.114.219303

  13. Huang, Fang

    1. Curcumin Attenuates Opioid Tolerance and Dependence by Inhibiting Ca2+/Calmodulin-Dependent Protein Kinase II α Activity
      Xiaoyu Hu, Fang Huang, Magdalena Szymusiak, Ying Liu and Zaijie Jim Wang
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 420-428; DOI: https://doi.org/10.1124/jpet.114.219303

I

  1. Impagnatiello, Maria Antonietta

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

J

  1. Jan, Yi-Hua

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  2. Jeha, Sima

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  3. Johnson, Philip L.

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

K

  1. Kale, Vijay P.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  2. Karol, Seth E.

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  3. Kester, Mark

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  4. Kim, Byeong Gwan

    1. Fexofenadine Regulates Nuclear Factor-κB Signaling and Endoplasmic Reticulum Stress in Intestinal Epithelial Cells and Ameliorates Acute and Chronic Colitis in Mice
      Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jaeyoung Chun and Joo Sung Kim
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 455-461; DOI: https://doi.org/10.1124/jpet.114.217844

  5. Kim, Ji Won

    1. Fexofenadine Regulates Nuclear Factor-κB Signaling and Endoplasmic Reticulum Stress in Intestinal Epithelial Cells and Ameliorates Acute and Chronic Colitis in Mice
      Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jaeyoung Chun and Joo Sung Kim
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 455-461; DOI: https://doi.org/10.1124/jpet.114.217844

  6. Kim, Joo Sung

    1. Fexofenadine Regulates Nuclear Factor-κB Signaling and Endoplasmic Reticulum Stress in Intestinal Epithelial Cells and Ameliorates Acute and Chronic Colitis in Mice
      Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jaeyoung Chun and Joo Sung Kim
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 455-461; DOI: https://doi.org/10.1124/jpet.114.217844

  7. Kimura, Haruhide

    1. In Vivo Pharmacological Characterization of TAK-063, a Potent and Selective Phosphodiesterase 10A Inhibitor with Antipsychotic-Like Activity in Rodents
      Kazunori Suzuki, Akina Harada, Eri Shiraishi and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 471-479; DOI: https://doi.org/10.1124/jpet.114.218552

  8. Koh, Seong-Joon

    1. Fexofenadine Regulates Nuclear Factor-κB Signaling and Endoplasmic Reticulum Stress in Intestinal Epithelial Cells and Ameliorates Acute and Chronic Colitis in Mice
      Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jaeyoung Chun and Joo Sung Kim
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 455-461; DOI: https://doi.org/10.1124/jpet.114.217844

  9. Koprowski, Stacy

    1. Thrombopoietin Receptor Agonists Protect Human Cardiac Myocytes from Injury by Activation of Cell Survival Pathways
      John E. Baker, Jidong Su, Stacy Koprowski, Anuradha Dhanasekaran, Tom P. Aufderheide and Garrett J. Gross
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 429-437; DOI: https://doi.org/10.1124/jpet.114.221747

  10. Kraut, Norbert

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  11. Kumar, Divya P.

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

L

  1. Laskin, Debra L.

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  2. Laskin, Jeffrey D.

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  3. Lebold, Terry P.

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  4. Lee, Kook Lae

    1. Fexofenadine Regulates Nuclear Factor-κB Signaling and Endoplasmic Reticulum Stress in Intestinal Epithelial Cells and Ameliorates Acute and Chronic Colitis in Mice
      Seong-Joon Koh, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Jaeyoung Chun and Joo Sung Kim
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 455-461; DOI: https://doi.org/10.1124/jpet.114.217844

  5. Lein, Pamela J.

    1. A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression
      Ana Cristina G. Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H. Nantz, Pamela J. Lein and Fredric Gorin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 438-447; DOI: https://doi.org/10.1124/jpet.114.220186

  6. Leung, Yat Hei

    1. Effects of β-Blockers and Tricyclic Antidepressants on the Activity of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2)
      Jennifer Lu, Veronique Michaud, Liliam Gabriela Guilarte Moya, Fleur Gaudette, Yat Hei Leung and Jacques Turgeon
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 552-558; DOI: https://doi.org/10.1124/jpet.114.219287

  7. Liu, Chengcheng

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  8. Liu, Ying

    1. Curcumin Attenuates Opioid Tolerance and Dependence by Inhibiting Ca2+/Calmodulin-Dependent Protein Kinase II α Activity
      Xiaoyu Hu, Fang Huang, Magdalena Szymusiak, Ying Liu and Zaijie Jim Wang
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 420-428; DOI: https://doi.org/10.1124/jpet.114.219303

  9. Lord, Brian

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  10. Loughran, Thomas P.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  11. Lovenberg, Timothy

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  12. Lu, Jennifer

    1. Effects of β-Blockers and Tricyclic Antidepressants on the Activity of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2)
      Jennifer Lu, Veronique Michaud, Liliam Gabriela Guilarte Moya, Fleur Gaudette, Yat Hei Leung and Jacques Turgeon
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 552-558; DOI: https://doi.org/10.1124/jpet.114.219287

M

  1. Mahavadi, Sunila

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

  2. Marchini, Gessica

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  3. Michaud, Veronique

    1. Effects of β-Blockers and Tricyclic Antidepressants on the Activity of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2)
      Jennifer Lu, Veronique Michaud, Liliam Gabriela Guilarte Moya, Fleur Gaudette, Yat Hei Leung and Jacques Turgeon
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 552-558; DOI: https://doi.org/10.1124/jpet.114.219287

  4. Mileo, Valentina

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  5. Mishin, Vladimir

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  6. Moll, Jürgen

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  7. Moretti, Elisa

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  8. Moretto, Nadia

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  9. Moya, Liliam Gabriela Guilarte

    1. Effects of β-Blockers and Tricyclic Antidepressants on the Activity of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2)
      Jennifer Lu, Veronique Michaud, Liliam Gabriela Guilarte Moya, Fleur Gaudette, Yat Hei Leung and Jacques Turgeon
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 552-558; DOI: https://doi.org/10.1124/jpet.114.219287

  10. Murthy, Karnam S.

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

N

  1. Nalli, Ancy D.

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

  2. Nantz, Michael H.

    1. A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression
      Ana Cristina G. Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H. Nantz, Pamela J. Lein and Fredric Gorin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 438-447; DOI: https://doi.org/10.1124/jpet.114.220186

  3. Nepomuceno, Diane

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

P

  1. Paine, Mary F.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

  2. Pastore, Fiorella

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  3. Pasupuleti, Nagarekha

    1. A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression
      Ana Cristina G. Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H. Nantz, Pamela J. Lein and Fredric Gorin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 438-447; DOI: https://doi.org/10.1124/jpet.114.220186

  4. Patacchini, Riccardo

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  5. Paterson, Blake

    1. Effect of Memantine on Cough Reflex Sensitivity: Translational Studies in Guinea Pigs and Humans
      Peter V. Dicpinigaitis, Brendan J. Canning, Rachel Garner and Blake Paterson
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 448-454; DOI: https://doi.org/10.1124/jpet.114.221218

  6. Pisano, Anna Rita

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  7. Poola, Bhaskar

    1. A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression
      Ana Cristina G. Grodzki, Bhaskar Poola, Nagarekha Pasupuleti, Michael H. Nantz, Pamela J. Lein and Fredric Gorin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 438-447; DOI: https://doi.org/10.1124/jpet.114.220186

  8. Preynat, Laurent

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  9. Proctor, William R.

    1. Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
      Tianxiang (Kevin) Han, William R. Proctor, Chester L. Costales, Hao Cai, Ruth S. Everett and Dhiren R. Thakker
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 519-528; DOI: https://doi.org/10.1124/jpet.114.220350

  10. Puccini, Paola

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  11. Pui, Ching-Hon

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  12. Puviani, Veronica

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

R

  1. Rajagopal, Senthilkumar

    1. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation
      Senthilkumar Rajagopal, Ancy D. Nalli, Divya P. Kumar, Sayak Bhattacharya, Wenhui Hu, Sunila Mahavadi, John R. Grider and Karnam S. Murthy
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 509-518; DOI: https://doi.org/10.1124/jpet.114.221929

  2. Ramsey, Laura B.

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  3. Relling, Mary V.

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  4. Reschke, Markus

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  5. Richardson, Jason R.

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  6. Rizzi, Andrea

    1. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  7. Roman, David L.

    1. Bias Analyses of Preclinical and Clinical D2 Dopamine Ligands: Studies with Immediate and Complex Signaling Pathways
      Tarsis F. Brust, Michael P. Hayes, David L. Roman, Kevin D. Burris and Val J. Watts
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 480-493; DOI: https://doi.org/10.1124/jpet.114.220293

  8. Roth, Mareike

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  9. Rudolph, Dorothea

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

S

  1. Sala, Angelo

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558
    2. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  2. Savarese, Fabio

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  3. Sharma, Arun

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  4. Shekhar, Anantha

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  5. Shelton, Jonathan

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  6. Shiraishi, Eri

    1. In Vivo Pharmacological Characterization of TAK-063, a Potent and Selective Phosphodiesterase 10A Inhibitor with Antipsychotic-Like Activity in Rodents
      Kazunori Suzuki, Akina Harada, Eri Shiraishi and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 471-479; DOI: https://doi.org/10.1124/jpet.114.218552

  7. Shireman, Brock T.

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  8. Smith, Colton

    1. Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity
      Christian A. Fernandez, Colton Smith, Seth E. Karol, Laura B. Ramsey, Chengcheng Liu, Ching-Hon Pui, Sima Jeha, William E. Evans, Fred D. Finkelman and Mary V. Relling
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 541-551; DOI: https://doi.org/10.1124/jpet.114.220780

  9. Sommer, Christoph

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  10. Stellari, Fabio Franco

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

  11. Su, Jidong

    1. Thrombopoietin Receptor Agonists Protect Human Cardiac Myocytes from Injury by Activation of Cell Survival Pathways
      John E. Baker, Jidong Su, Stacy Koprowski, Anuradha Dhanasekaran, Tom P. Aufderheide and Garrett J. Gross
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 429-437; DOI: https://doi.org/10.1124/jpet.114.221747

  12. Sung, Shen-Shu

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  13. Suzuki, Kazunori

    1. In Vivo Pharmacological Characterization of TAK-063, a Potent and Selective Phosphodiesterase 10A Inhibitor with Antipsychotic-Like Activity in Rodents
      Kazunori Suzuki, Akina Harada, Eri Shiraishi and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 471-479; DOI: https://doi.org/10.1124/jpet.114.218552

  14. Szymusiak, Magdalena

    1. Curcumin Attenuates Opioid Tolerance and Dependence by Inhibiting Ca2+/Calmodulin-Dependent Protein Kinase II α Activity
      Xiaoyu Hu, Fang Huang, Magdalena Szymusiak, Ying Liu and Zaijie Jim Wang
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 420-428; DOI: https://doi.org/10.1124/jpet.114.219303

T

  1. Thakker, Dhiren R.

    1. Four Cation-Selective Transporters Contribute to Apical Uptake and Accumulation of Metformin in Caco-2 Cell Monolayers
      Tianxiang (Kevin) Han, William R. Proctor, Chester L. Costales, Hao Cai, Ruth S. Everett and Dhiren R. Thakker
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 519-528; DOI: https://doi.org/10.1124/jpet.114.220350

  2. Tontsch-Grunt, Ulrike

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

  3. Turgeon, Jacques

    1. Effects of β-Blockers and Tricyclic Antidepressants on the Activity of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2)
      Jennifer Lu, Veronique Michaud, Liliam Gabriela Guilarte Moya, Fleur Gaudette, Yat Hei Leung and Jacques Turgeon
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 552-558; DOI: https://doi.org/10.1124/jpet.114.219287

V

  1. Vanderah, Todd W.

    1. Mechanistic Basis of Altered Morphine Disposition in Nonalcoholic Steatohepatitis
      Anika L. Dzierlenga, John D. Clarke, Tiffanie L. Hargraves, Garrett R. Ainslie, Todd W. Vanderah, Mary F. Paine and Nathan J. Cherrington
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 462-470; DOI: https://doi.org/10.1124/jpet.114.220764

  2. Villetti, Gino

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558
    2. CHF6001 I: A Novel Highly Potent and Selective Phosphodiesterase 4 Inhibitor with Robust Anti-Inflammatory Activity and Suitable for Topical Pulmonary Administration
      Nadia Moretto, Paola Caruso, Raffaella Bosco, Gessica Marchini, Fiorella Pastore, Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Eleonora Ghidini, Renato De Fanti, Carmelida Capaldi, Laura Carzaniga, Emilio Hirsch, Carola Buccellati, Angelo Sala, Chiara Carnini, Riccardo Patacchini, Maurizio Delcanale, Maurizio Civelli, Gino Villetti and Fabrizio Facchinetti
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.220541

  3. Volta, Roberta

    1. CHF6001 II: A Novel Phosphodiesterase 4 Inhibitor, Suitable for Topical Pulmonary Administration—In Vivo Preclinical Pharmacology Profile Defines a Potent Anti-Inflammatory Compound with a Wide Therapeutic Window
      Gino Villetti, Chiara Carnini, Loredana Battipaglia, Laurent Preynat, Pier Tonino Bolzoni, Franco Bassani, Paola Caruso, Marco Bergamaschi, Anna Rita Pisano, Veronica Puviani, Fabio Franco Stellari, Valentina Cenacchi, Roberta Volta, Vittorio Bertacche, Valentina Mileo, Valentina Bagnacani, Elisa Moretti, Paola Puccini, Silvia Catinella, Fabrizio Facchinetti, Angelo Sala and Maurizio Civelli
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 568-578; DOI: https://doi.org/10.1124/jpet.114.220558

W

  1. Wang, Hong-Gang

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  2. Wang, Zaijie Jim

    1. Curcumin Attenuates Opioid Tolerance and Dependence by Inhibiting Ca2+/Calmodulin-Dependent Protein Kinase II α Activity
      Xiaoyu Hu, Fang Huang, Magdalena Szymusiak, Ying Liu and Zaijie Jim Wang
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 420-428; DOI: https://doi.org/10.1124/jpet.114.219303

  3. Watts, Val J.

    1. Bias Analyses of Preclinical and Clinical D2 Dopamine Ligands: Studies with Immediate and Complex Signaling Pathways
      Tarsis F. Brust, Michael P. Hayes, David L. Roman, Kevin D. Burris and Val J. Watts
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 480-493; DOI: https://doi.org/10.1124/jpet.114.220293

  4. Wennerholm, Michelle

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

  5. Wernitznig, Andreas

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150

Y

  1. Yang, Shaojun

    1. Sulfa Drugs Inhibit Sepiapterin Reduction and Chemical Redox Cycling by Sepiapterin Reductase
      Shaojun Yang, Yi-Hua Jan, Vladimir Mishin, Jason R. Richardson, Muhammad M. Hossain, Ned D. Heindel, Diane E. Heck, Debra L. Laskin and Jeffrey D. Laskin
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 529-540; DOI: https://doi.org/10.1124/jpet.114.221572

  2. Yun, Jong K.

    1. The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
      Taryn E. Dick, Jeremy A. Hengst, Todd E. Fox, Ashley L. Colledge, Vijay P. Kale, Shen-Shu Sung, Arun Sharma, Shantu Amin, Thomas P. Loughran, Mark Kester, Hong-Gang Wang and Jong K. Yun
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 494-508; DOI: https://doi.org/10.1124/jpet.114.219659

  3. Yun, Sujin

    1. A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects
      Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas Carruthers, Timothy Lovenberg and Christine Dugovic
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 590-601; DOI: https://doi.org/10.1124/jpet.114.220392

Z

  1. Zuber, Johannes

    1. Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
      Dorothea Rudolph, Maria Antonietta Impagnatiello, Claudia Blaukopf, Christoph Sommer, Daniel W. Gerlich, Mareike Roth, Ulrike Tontsch-Grunt, Andreas Wernitznig, Fabio Savarese, Marco H. Hofmann, Christoph Albrecht, Lena Geiselmann, Markus Reschke, Pilar Garin-Chesa, Johannes Zuber, Jürgen Moll, Günther R. Adolf and Norbert Kraut
      Journal of Pharmacology and Experimental Therapeutics March 2015, 352 (3) 579-589; DOI: https://doi.org/10.1124/jpet.114.221150
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