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Research ArticleDrug Discovery and Translational Medicine

Evaluation of AaDOP2 Receptor Antagonists Reveals Antidepressants and Antipsychotics as Novel Lead Molecules for Control of the Yellow Fever Mosquito, Aedes aegypti

Jason M. Conley, Jason M. Meyer, Andrew B. Nuss, Trevor B. Doyle, Sergey N. Savinov, Catherine A. Hill and Val J. Watts
Journal of Pharmacology and Experimental Therapeutics January 2015, 352 (1) 53-60; DOI: https://doi.org/10.1124/jpet.114.219717
Jason M. Conley
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Jason M. Meyer
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Andrew B. Nuss
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Trevor B. Doyle
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Sergey N. Savinov
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Catherine A. Hill
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Val J. Watts
Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
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Article Information

vol. 352 no. 1 53-60
DOI 
https://doi.org/10.1124/jpet.114.219717
PubMed 
25332454

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 4, 2014
  • Accepted October 17, 2014
  • Published online November 18, 2014.

Article Versions

  • Earlier version (October 20, 2014 - 11:26).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jason M. Conley,
  2. Jason M. Meyer,
  3. Andrew B. Nuss,
  4. Trevor B. Doyle,
  5. Sergey N. Savinov,
  6. Catherine A. Hill, and
  7. Val J. Watts
  1. Department of Medicinal Chemistry and Molecular Pharmacology (J.M.C., T.B.D., V.J.W.), Department of Entomology (J.M.M., A.B.N., C.A.H.), and Bindley Bioscience Center, Discovery Park (S.N.S.), Purdue University, West Lafayette, Indiana
  1. Address correspondence to:
    Val J. Watts, 575 Stadium Mall Dr., Purdue University, West Lafayette, IN 47097. E-mail: wattsv{at}purdue.edu
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Journal of Pharmacology and Experimental Therapeutics: 352 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 352, Issue 1
1 Jan 2015
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Research ArticleDrug Discovery and Translational Medicine

Antidepressants and Antipsychotics as Lead Insecticides

Jason M. Conley, Jason M. Meyer, Andrew B. Nuss, Trevor B. Doyle, Sergey N. Savinov, Catherine A. Hill and Val J. Watts
Journal of Pharmacology and Experimental Therapeutics January 1, 2015, 352 (1) 53-60; DOI: https://doi.org/10.1124/jpet.114.219717

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Research ArticleDrug Discovery and Translational Medicine

Antidepressants and Antipsychotics as Lead Insecticides

Jason M. Conley, Jason M. Meyer, Andrew B. Nuss, Trevor B. Doyle, Sergey N. Savinov, Catherine A. Hill and Val J. Watts
Journal of Pharmacology and Experimental Therapeutics January 1, 2015, 352 (1) 53-60; DOI: https://doi.org/10.1124/jpet.114.219717
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