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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Regulation of a Notch3-Hes1 Pathway and Protective Effect by a Tocopherol-Omega Alkanol Chain Derivative in Muscle Atrophy

Yannick von Grabowiecki, Cynthia Licona, Lavinia Palamiuc, Paula Abreu, Vania Vidimar, Djalil Coowar, Georg Mellitzer and Christian Gaiddon
Journal of Pharmacology and Experimental Therapeutics January 2015, 352 (1) 23-32; DOI: https://doi.org/10.1124/jpet.114.216879
Yannick von Grabowiecki
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Cynthia Licona
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Lavinia Palamiuc
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Paula Abreu
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Vania Vidimar
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Djalil Coowar
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Georg Mellitzer
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Christian Gaiddon
INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
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Article Information

vol. 352 no. 1 23-32
DOI 
https://doi.org/10.1124/jpet.114.216879
PubMed 
25326132

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 22, 2014
  • Accepted October 17, 2014
  • Published online November 18, 2014.

Article Versions

  • Earlier version (October 17, 2014 - 12:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yannick von Grabowiecki,
  2. Cynthia Licona,
  3. Lavinia Palamiuc,
  4. Paula Abreu,
  5. Vania Vidimar,
  6. Djalil Coowar,
  7. Georg Mellitzer, and
  8. Christian Gaiddon
  1. INSERM U1113, Molecular Mechanisms of Stress Response and Pathologies, Strasbourg, France (Y.v.G., C.L., P.A., V.V., G.M., C.G.); Faculté de Médecine de Strasbourg, Strasbourg University, Strasbourg, France (Y.v.G., C.L., L.P., P.A., V.V., G.M., C.G.); and AxoGlia Therapeutics, Fentange, Luxembourg (D.C.)
  1. Address correspondence to:
    Christian Gaiddon, INSERM U1113, 3 avenue Molière, Strasbourg, 67200, France. E-mail: Gaiddon{at}unistra.fr
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Journal of Pharmacology and Experimental Therapeutics: 352 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 352, Issue 1
1 Jan 2015
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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Tocopherol and Flavanoid Activity on Muscle via Notch

Yannick von Grabowiecki, Cynthia Licona, Lavinia Palamiuc, Paula Abreu, Vania Vidimar, Djalil Coowar, Georg Mellitzer and Christian Gaiddon
Journal of Pharmacology and Experimental Therapeutics January 1, 2015, 352 (1) 23-32; DOI: https://doi.org/10.1124/jpet.114.216879

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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Tocopherol and Flavanoid Activity on Muscle via Notch

Yannick von Grabowiecki, Cynthia Licona, Lavinia Palamiuc, Paula Abreu, Vania Vidimar, Djalil Coowar, Georg Mellitzer and Christian Gaiddon
Journal of Pharmacology and Experimental Therapeutics January 1, 2015, 352 (1) 23-32; DOI: https://doi.org/10.1124/jpet.114.216879
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