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Index by author

December 01, 2014; Volume 351,Issue 3

A

  1. Agbor, Larry N.

    1. Role of CYP1A1 in Modulating the Vascular and Blood Pressure Benefits of Omega-3 Polyunsaturated Fatty Acids
      Larry N. Agbor, Elani F. Wiest, Michael Rothe, Wolf-Hagen Schunck and Mary K. Walker
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 688-698; DOI: https://doi.org/10.1124/jpet.114.219535

  2. Ainslie, Garrett R.

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

  3. Aluisio, Leah

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  4. Andoh, Tsugunobu

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

B

  1. Bailey, Jessica M.

    1. Tolerance and Cross-Tolerance to Head Twitch Behavior Elicited by Phenethylamine- and Tryptamine-Derived Hallucinogens in Mice
      Douglas A. Smith, Jessica M. Bailey, Diarria Williams and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 485-491; DOI: https://doi.org/10.1124/jpet.114.219337

  2. Baker, Dale C.

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  3. Beaulac, Holly J.

    1. Biphasic Modulation of Paracellular Claudin-5 Expression in Mouse Brain Endothelial Cells Is Mediated through the Phosphoinositide-3-Kinase/AKT Pathway
      Ryan B. Camire, Holly J. Beaulac, Stephanie A. Brule, Annie I. McGregor, Emily E. Lauria and Colin L. Willis
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 654-662; DOI: https://doi.org/10.1124/jpet.114.218339

  4. Beeson, Craig C.

    1. Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice
      Sean R. Jesinkey, Midhun C. Korrapati, Kyle A. Rasbach, Craig C. Beeson and Rick G. Schnellmann
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 663-673; DOI: https://doi.org/10.1124/jpet.114.217380

  5. Betz, Andreas

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  6. Bhattacharya, Anindya

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  7. Blier, Pierre

    1. Acute Effects of Brexpiprazole on Serotonin, Dopamine, and Norepinephrine Systems: An In Vivo Electrophysiologic Characterization
      Chris A. Oosterhof, Mostafa El Mansari and Pierre Blier
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 585-595; DOI: https://doi.org/10.1124/jpet.114.218578

  8. Bloch, Kenneth D.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  9. Bonaventure, Pascal

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  10. Brule, Stephanie A.

    1. Biphasic Modulation of Paracellular Claudin-5 Expression in Mouse Brain Endothelial Cells Is Mediated through the Phosphoinositide-3-Kinase/AKT Pathway
      Ryan B. Camire, Holly J. Beaulac, Stephanie A. Brule, Annie I. McGregor, Emily E. Lauria and Colin L. Willis
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 654-662; DOI: https://doi.org/10.1124/jpet.114.218339

  11. Buschauer, Armin

    1. No Evidence for Histamine H4 Receptor in Human Monocytes
      Kristin Werner, Detlef Neumann, Armin Buschauer and Roland Seifert
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 519-526; DOI: https://doi.org/10.1124/jpet.114.218107

C

  1. Camire, Ryan B.

    1. Biphasic Modulation of Paracellular Claudin-5 Expression in Mouse Brain Endothelial Cells Is Mediated through the Phosphoinositide-3-Kinase/AKT Pathway
      Ryan B. Camire, Holly J. Beaulac, Stephanie A. Brule, Annie I. McGregor, Emily E. Lauria and Colin L. Willis
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 654-662; DOI: https://doi.org/10.1124/jpet.114.218339

  2. Campagne, Menno van Lookeren

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  3. Carruthers, Nicholas

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  4. Casella, Luigi

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  5. Ceusters, Marc

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  6. Chaki, Shigeyuki

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  7. Chappell, Alfred

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  8. Chen, Xueqin

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703

  9. Cheng, Jie

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  10. Coffey, Greg

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  11. Connolly, Elizabeth A.

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

D

  1. Damico-Beyer, Lisa A.

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  2. Das, Aditi

    1. Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase
      Daniel R. McDougle, Amogh Kambalyal, Daryl D. Meling and Aditi Das
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 616-627; DOI: https://doi.org/10.1124/jpet.114.216598

  3. Davancaze, Teresa

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  4. Deak, Terrence

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  5. DeForge, Laura E.

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  6. DeGuzman, Francis

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  7. Dib, Martin

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  8. Do, Nhue

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  9. Drinkenburg, Wilhelmus

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

E

  1. El Mansari, Mostafa

    1. Acute Effects of Brexpiprazole on Serotonin, Dopamine, and Norepinephrine Systems: An In Vivo Electrophysiologic Characterization
      Chris A. Oosterhof, Mostafa El Mansari and Pierre Blier
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 585-595; DOI: https://doi.org/10.1124/jpet.114.218578

  2. Engers, Darren W.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

F

  1. Fang, Zhong-Ze

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  2. Fantegrossi, William E.

    1. Tolerance and Cross-Tolerance to Head Twitch Behavior Elicited by Phenethylamine- and Tryptamine-Derived Hallucinogens in Mice
      Douglas A. Smith, Jessica M. Bailey, Diarria Williams and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 485-491; DOI: https://doi.org/10.1124/jpet.114.219337

  3. Fink, Brian D.

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  4. Frazer-Abel, Ashley

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  5. Frist, Audrey

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  6. Fujii, Masanori

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

G

  1. Gao, Zhaobing

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703

  2. Giclas, Patricia C.

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  3. Gonzalez, Frank J.

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  4. Good, Jeremy

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  5. Grobe, Justin L.

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  6. Guo, Deng Fu

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

H

  1. Hahn, Alana M.

    1. Interleukin-Driven Insulin-Like Growth Factor Promotes Prostatic Inflammatory Hyperplasia
      Alana M. Hahn, Jason D. Myers, Eliza K. McFarland, Sanghee Lee and Travis J. Jerde
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 605-615; DOI: https://doi.org/10.1124/jpet.114.218693

  2. Hass, Philip E.

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  3. Hatano, Noriyuki

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  4. Haughney, Peter C.

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  5. Henry, Scott P.

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  6. Herlein, Judith A.

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  7. Hikichi, Hirohiko

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  8. Hiyoshi, Tetsuaki

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  9. Ho, Karen

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  10. Hollenbach, Stanley J.

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  11. Hong, Charles C.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  12. Hopkins, Corey R.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  13. Huang, Cathy X.

    1. Early and Transient Sodium-Hydrogen Exchanger Isoform 1 Inhibition Attenuates Subsequent Cardiac Hypertrophy and Heart Failure Following Coronary Artery Ligation
      Ana Kilić, Cathy X. Huang, Venkatesh Rajapurohitam, Jeffrey B. Madwed and Morris Karmazyn
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 492-499; DOI: https://doi.org/10.1124/jpet.114.217091

  14. Hull, J. Heyward

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

I

  1. Iida, Izumi

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  2. Inagaki, Mayuko

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

J

  1. Jerde, Travis J.

    1. Interleukin-Driven Insulin-Like Growth Factor Promotes Prostatic Inflammatory Hyperplasia
      Alana M. Hahn, Jason D. Myers, Eliza K. McFarland, Sanghee Lee and Travis J. Jerde
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 605-615; DOI: https://doi.org/10.1124/jpet.114.218693

  2. Jesinkey, Sean R.

    1. Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice
      Sean R. Jesinkey, Midhun C. Korrapati, Kyle A. Rasbach, Craig C. Beeson and Rick G. Schnellmann
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 663-673; DOI: https://doi.org/10.1124/jpet.114.217380

  3. Jiang, Hualiang

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703

K

  1. Kagaya, Kenta

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  2. Kambalyal, Amogh

    1. Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase
      Daniel R. McDougle, Amogh Kambalyal, Daryl D. Meling and Aditi Das
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 616-627; DOI: https://doi.org/10.1124/jpet.114.216598

  3. Kanatsuka, Saki

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  4. Karasawa, Jun-ichi

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  5. Karmazyn, Morris

    1. Early and Transient Sodium-Hydrogen Exchanger Isoform 1 Inhibition Attenuates Subsequent Cardiac Hypertrophy and Heart Failure Following Coronary Artery Ligation
      Ana Kilić, Cathy X. Huang, Venkatesh Rajapurohitam, Jeffrey B. Madwed and Morris Karmazyn
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 492-499; DOI: https://doi.org/10.1124/jpet.114.217091

  6. Karp, Seth J.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  7. Kerns, Robert J.

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  8. Kilić, Ana

    1. Early and Transient Sodium-Hydrogen Exchanger Isoform 1 Inhibition Attenuates Subsequent Cardiac Hypertrophy and Heart Failure Following Coronary Artery Ligation
      Ana Kilić, Cathy X. Huang, Venkatesh Rajapurohitam, Jeffrey B. Madwed and Morris Karmazyn
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 492-499; DOI: https://doi.org/10.1124/jpet.114.217091

  9. Kimura, Shioko

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  10. Kino, Yurika

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  11. Korrapati, Midhun C.

    1. Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice
      Sean R. Jesinkey, Midhun C. Korrapati, Kyle A. Rasbach, Craig C. Beeson and Rick G. Schnellmann
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 663-673; DOI: https://doi.org/10.1124/jpet.114.217380

  12. Kulkarni, Chaitanya

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  13. Kuraishi, Yasushi

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  14. Kuramitsu, Kaori

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

L

  1. Lauria, Emily E.

    1. Biphasic Modulation of Paracellular Claudin-5 Expression in Mouse Brain Endothelial Cells Is Mediated through the Phosphoinositide-3-Kinase/AKT Pathway
      Ryan B. Camire, Holly J. Beaulac, Stephanie A. Brule, Annie I. McGregor, Emily E. Lauria and Colin L. Willis
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 654-662; DOI: https://doi.org/10.1124/jpet.114.218339

  2. Le, Kha N.

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  3. Lee, Sanghee

    1. Interleukin-Driven Insulin-Like Growth Factor Promotes Prostatic Inflammatory Hyperplasia
      Alana M. Hahn, Jason D. Myers, Eliza K. McFarland, Sanghee Lee and Travis J. Jerde
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 605-615; DOI: https://doi.org/10.1124/jpet.114.218693

  4. Letavic, Michael A.

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  5. Li, Ping

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703

  6. Li, Yingxin

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

  7. Lindsley, Craig W.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  8. Lochner, Martin

    1. The Antimalarial Drug Proguanil Is an Antagonist at 5-HT3 Receptors
      Martin Lochner and Andrew J. Thompson
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 674-684; DOI: https://doi.org/10.1124/jpet.114.218461

  9. Lord, Brian

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  10. Lovenberg, Timothy W.

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  11. Loyet, Kelly M.

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

M

  1. Madwed, Jeffrey B.

    1. Early and Transient Sodium-Hydrogen Exchanger Isoform 1 Inhibition Attenuates Subsequent Cardiac Hypertrophy and Heart Failure Following Coronary Artery Ligation
      Ana Kilić, Cathy X. Huang, Venkatesh Rajapurohitam, Jeffrey B. Madwed and Morris Karmazyn
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 492-499; DOI: https://doi.org/10.1124/jpet.114.217091

  2. Marumo, Toshiyuki

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  3. Masuzaki, Ryota

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  4. Matsuba, Sayo

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  5. McDougle, Daniel R.

    1. Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase
      Daniel R. McDougle, Amogh Kambalyal, Daryl D. Meling and Aditi Das
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 616-627; DOI: https://doi.org/10.1124/jpet.114.216598

  6. McFarland, Eliza K.

    1. Interleukin-Driven Insulin-Like Growth Factor Promotes Prostatic Inflammatory Hyperplasia
      Alana M. Hahn, Jason D. Myers, Eliza K. McFarland, Sanghee Lee and Travis J. Jerde
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 605-615; DOI: https://doi.org/10.1124/jpet.114.218693

  7. McGregor, Annie I.

    1. Biphasic Modulation of Paracellular Claudin-5 Expression in Mouse Brain Endothelial Cells Is Mediated through the Phosphoinositide-3-Kinase/AKT Pathway
      Ryan B. Camire, Holly J. Beaulac, Stephanie A. Brule, Annie I. McGregor, Emily E. Lauria and Colin L. Willis
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 654-662; DOI: https://doi.org/10.1124/jpet.114.218339

  8. Meling, Daryl D.

    1. Endocannabinoids Anandamide and 2-Arachidonoylglycerol Are Substrates for Human CYP2J2 Epoxygenase
      Daniel R. McDougle, Amogh Kambalyal, Daryl D. Meling and Aditi Das
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 616-627; DOI: https://doi.org/10.1124/jpet.114.216598

  9. Mizoguchi, Shizuka

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  10. Monti, Martina

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  11. Monzani, Enrico

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  12. Morbidelli, Lucia

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  13. Morimoto, Alyssa

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  14. Muraki, Katsuhiko

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  15. Myers, Jason D.

    1. Interleukin-Driven Insulin-Like Growth Factor Promotes Prostatic Inflammatory Hyperplasia
      Alana M. Hahn, Jason D. Myers, Eliza K. McFarland, Sanghee Lee and Travis J. Jerde
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 605-615; DOI: https://doi.org/10.1124/jpet.114.218693

N

  1. Nagaoka, Kenjiro

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  2. Nakazono, Yurika

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  3. Neff, Robert A.

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  4. Neumann, Detlef

    1. No Evidence for Histamine H4 Receptor in Human Monocytes
      Kristin Werner, Detlef Neumann, Armin Buschauer and Roland Seifert
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 519-526; DOI: https://doi.org/10.1124/jpet.114.218107

  5. Niwa, Satomi

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

O

  1. Ohya, Susumu

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  2. Okamoto, Minoru

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  3. Oosterhof, Chris A.

    1. Acute Effects of Brexpiprazole on Serotonin, Dopamine, and Norepinephrine Systems: An In Vivo Electrophysiologic Characterization
      Chris A. Oosterhof, Mostafa El Mansari and Pierre Blier
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 585-595; DOI: https://doi.org/10.1124/jpet.114.218578

  4. Oya, Yuki

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

P

  1. Paine, Mary F.

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

  2. Pak, Yvonne

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  3. Pandey, Anjali

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  4. Pangburn, Michael K.

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  5. Pasotti, Luca

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  6. Puccetti, Luca

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

Q

  1. Qu, Aijuan

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

R

  1. Rahmouni, Kamal

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  2. Rajapurohitam, Venkatesh

    1. Early and Transient Sodium-Hydrogen Exchanger Isoform 1 Inhibition Attenuates Subsequent Cardiac Hypertrophy and Heart Failure Following Coronary Artery Ligation
      Ana Kilić, Cathy X. Huang, Venkatesh Rajapurohitam, Jeffrey B. Madwed and Morris Karmazyn
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 492-499; DOI: https://doi.org/10.1124/jpet.114.217091

  3. Rasbach, Kyle A.

    1. Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice
      Sean R. Jesinkey, Midhun C. Korrapati, Kyle A. Rasbach, Craig C. Beeson and Rick G. Schnellmann
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 663-673; DOI: https://doi.org/10.1124/jpet.114.217380

  4. Ray, Kevin

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

  5. Reynolds, Paul R.

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  6. Roggeri, Riccardo

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  7. Rothe, Michael

    1. Role of CYP1A1 in Modulating the Vascular and Blood Pressure Benefits of Omega-3 Polyunsaturated Fatty Acids
      Larry N. Agbor, Elani F. Wiest, Michael Rothe, Wolf-Hagen Schunck and Mary K. Walker
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 688-698; DOI: https://doi.org/10.1124/jpet.114.219535

S

  1. Saito, Yukako

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  2. Sakai, Akiho

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  3. Sasaki, Atsushi

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  4. Scarlett, Yolanda V.

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

  5. Schnellmann, Rick G.

    1. Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice
      Sean R. Jesinkey, Midhun C. Korrapati, Kyle A. Rasbach, Craig C. Beeson and Rick G. Schnellmann
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 663-673; DOI: https://doi.org/10.1124/jpet.114.217380

  6. Schunck, Wolf-Hagen

    1. Role of CYP1A1 in Modulating the Vascular and Blood Pressure Benefits of Omega-3 Polyunsaturated Fatty Acids
      Larry N. Agbor, Elani F. Wiest, Michael Rothe, Wolf-Hagen Schunck and Mary K. Walker
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 688-698; DOI: https://doi.org/10.1124/jpet.114.219535

  7. Seifert, Roland

    1. No Evidence for Histamine H4 Receptor in Human Monocytes
      Kristin Werner, Detlef Neumann, Armin Buschauer and Roland Seifert
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 519-526; DOI: https://doi.org/10.1124/jpet.114.218107

  8. Shen, Lijiang

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  9. Shiro, Mai

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  10. Shoblock, James R.

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

  11. Sinha, Uma

    1. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer
      Greg Coffey, Andreas Betz, Francis DeGuzman, Yvonne Pak, Mayuko Inagaki, Dale C. Baker, Stanley J. Hollenbach, Anjali Pandey and Uma Sinha
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 538-548; DOI: https://doi.org/10.1124/jpet.114.218164

  12. Sivitz, William I.

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  13. Smith, Douglas A.

    1. Tolerance and Cross-Tolerance to Head Twitch Behavior Elicited by Phenethylamine- and Tryptamine-Derived Hallucinogens in Mice
      Douglas A. Smith, Jessica M. Bailey, Diarria Williams and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 485-491; DOI: https://doi.org/10.1124/jpet.114.219337

  14. Solito, Raffaella

    1. Protective Effects of Novel Metal-Nonoates on the Cellular Components of the Vascular System
      Martina Monti, Raffaella Solito, Luca Puccetti, Luca Pasotti, Riccardo Roggeri, Enrico Monzani, Luigi Casella and Lucia Morbidelli
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 500-509; DOI: https://doi.org/10.1124/jpet.114.218404

  15. Sturgeon, Lizette

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  16. Suzuki, Takayoshi

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

T

  1. Takahata, Hiroki

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  2. Tamita, Tomoko

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  3. Tanaka, Naoki

    1. Activation of Intestinal Human Pregnane X Receptor Protects against Azoxymethane/Dextran Sulfate Sodium–Induced Colon Cancer
      Jie Cheng, Zhong-Ze Fang, Kenjiro Nagaoka, Minoru Okamoto, Aijuan Qu, Naoki Tanaka, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 559-567; DOI: https://doi.org/10.1124/jpet.114.215913

  4. Taniguchi, Hiroyuki

    1. A Mouse Model of Peripheral Postischemic Dysesthesia: Involvement of Reperfusion-Induced Oxidative Stress and TRPA1 Channel
      Atsushi Sasaki, Shizuka Mizoguchi, Kenta Kagaya, Mai Shiro, Akiho Sakai, Tsugunobu Andoh, Yurika Kino, Hiroyuki Taniguchi, Yukako Saito, Hiroki Takahata and Yasushi Kuraishi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 568-575; DOI: https://doi.org/10.1124/jpet.114.217570

  5. Thompson, Andrew J.

    1. The Antimalarial Drug Proguanil Is an Antagonist at 5-HT3 Receptors
      Martin Lochner and Andrew J. Thompson
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 674-684; DOI: https://doi.org/10.1124/jpet.114.218461

  6. Tomishima, Yasumitsu

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  7. Tsugawa, Daisuke

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

U

  1. Urabe, Hiroki

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

V

  1. Varlinskaya, Elena I.

    1. Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432
      Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg and Anindya Bhattacharya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 628-641; DOI: https://doi.org/10.1124/jpet.114.218487

W

  1. Walker, Mary K.

    1. Role of CYP1A1 in Modulating the Vascular and Blood Pressure Benefits of Omega-3 Polyunsaturated Fatty Acids
      Larry N. Agbor, Elani F. Wiest, Michael Rothe, Wolf-Hagen Schunck and Mary K. Walker
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 688-698; DOI: https://doi.org/10.1124/jpet.114.219535

  2. Wang, Xiangdan

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  3. Weidemann, Benjamin J.

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  4. Werner, Kristin

    1. No Evidence for Histamine H4 Receptor in Human Monocytes
      Kristin Werner, Detlef Neumann, Armin Buschauer and Roland Seifert
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 519-526; DOI: https://doi.org/10.1124/jpet.114.218107

  5. Wiest, Elani F.

    1. Role of CYP1A1 in Modulating the Vascular and Blood Pressure Benefits of Omega-3 Polyunsaturated Fatty Acids
      Larry N. Agbor, Elani F. Wiest, Michael Rothe, Wolf-Hagen Schunck and Mary K. Walker
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 688-698; DOI: https://doi.org/10.1124/jpet.114.219535

  6. Williams, Diarria

    1. Tolerance and Cross-Tolerance to Head Twitch Behavior Elicited by Phenethylamine- and Tryptamine-Derived Hallucinogens in Mice
      Douglas A. Smith, Jessica M. Bailey, Diarria Williams and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 485-491; DOI: https://doi.org/10.1124/jpet.114.219337

  7. Willis, Colin L.

    1. Biphasic Modulation of Paracellular Claudin-5 Expression in Mouse Brain Endothelial Cells Is Mediated through the Phosphoinositide-3-Kinase/AKT Pathway
      Ryan B. Camire, Holly J. Beaulac, Stephanie A. Brule, Annie I. McGregor, Emily E. Lauria and Colin L. Willis
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 654-662; DOI: https://doi.org/10.1124/jpet.114.218339

  8. Wolf, Kristina K.

    1. Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates
      Garrett R. Ainslie, Kristina K. Wolf, Yingxin Li, Elizabeth A. Connolly, Yolanda V. Scarlett, J. Heyward Hull and Mary F. Paine
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 576-584; DOI: https://doi.org/10.1124/jpet.114.216838

  9. Wong, Maureen

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

Y

  1. Yang, Huaiyu

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703

  2. Yang, Jihong

    1. Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration
      Kelly M. Loyet, Jeremy Good, Teresa Davancaze, Lizette Sturgeon, Xiangdan Wang, Jihong Yang, Kha N. Le, Maureen Wong, Philip E. Hass, Menno van Lookeren Campagne, Peter C. Haughney, Alyssa Morimoto, Lisa A. Damico-Beyer and Laura E. DeForge
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 527-537; DOI: https://doi.org/10.1124/jpet.114.215921

  3. Yasuhara, Akito

    1. Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor
      Tetsuaki Hiyoshi, Toshiyuki Marumo, Hirohiko Hikichi, Yasumitsu Tomishima, Hiroki Urabe, Tomoko Tamita, Izumi Iida, Akito Yasuhara, Jun-ichi Karasawa and Shigeyuki Chaki
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 642-653; DOI: https://doi.org/10.1124/jpet.114.218651

  4. Younis, Husam

    1. Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans
      Lijiang Shen, Ashley Frazer-Abel, Paul R. Reynolds, Patricia C. Giclas, Alfred Chappell, Michael K. Pangburn, Husam Younis and Scott P. Henry
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 709-717; DOI: https://doi.org/10.1124/jpet.114.219378

  5. Yu, Liping

    1. A Mitochondrial-Targeted Coenzyme Q Analog Prevents Weight Gain and Ameliorates Hepatic Dysfunction in High-Fat–Fed Mice
      Brian D. Fink, Judith A. Herlein, Deng Fu Guo, Chaitanya Kulkarni, Benjamin J. Weidemann, Liping Yu, Justin L. Grobe, Kamal Rahmouni, Robert J. Kerns and William I. Sivitz
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 699-708; DOI: https://doi.org/10.1124/jpet.114.219329

  6. Yu, Paul B.

    1. Specific Activin Receptor–Like Kinase 3 Inhibitors Enhance Liver Regeneration
      Daisuke Tsugawa, Yuki Oya, Ryota Masuzaki, Kevin Ray, Darren W. Engers, Martin Dib, Nhue Do, Kaori Kuramitsu, Karen Ho, Audrey Frist, Paul B. Yu, Kenneth D. Bloch, Craig W. Lindsley, Corey R. Hopkins, Charles C. Hong and Seth J. Karp
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 549-558; DOI: https://doi.org/10.1124/jpet.114.216903

Z

  1. Zhan, Peng

    1. Downregulation of Ca2+-Activated Cl− Channel TMEM16A by the Inhibition of Histone Deacetylase in TMEM16A-Expressing Cancer Cells
      Sayo Matsuba, Satomi Niwa, Katsuhiko Muraki, Saki Kanatsuka, Yurika Nakazono, Noriyuki Hatano, Masanori Fujii, Peng Zhan, Takayoshi Suzuki and Susumu Ohya
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 510-518; DOI: https://doi.org/10.1124/jpet.114.217315

  2. Zhang, Qiansen

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703

  3. Zheng, Yueming

    1. The Human Ether-A-Go-Go–Related Gene Activator NS1643 Enhances Epilepsy-Associated KCNQ Channels
      Ping Li, Xueqin Chen, Qiansen Zhang, Yueming Zheng, Hualiang Jiang, Huaiyu Yang and Zhaobing Gao
      Journal of Pharmacology and Experimental Therapeutics December 2014, 351 (3) 596-604; DOI: https://doi.org/10.1124/jpet.114.217703
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