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Research ArticleDrug Discovery and Translational Medicine

Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1

Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141
Shinji Yamazaki
Pharmacokinetics, Dynamics and Metabolism (S.Y., J.L.L., P.V.) and Oncology Research Unit (H.Y.Z., H.W., T.S.), Pfizer Worldwide Research & Development, San Diego, California
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Justine L. Lam
Pharmacokinetics, Dynamics and Metabolism (S.Y., J.L.L., P.V.) and Oncology Research Unit (H.Y.Z., H.W., T.S.), Pfizer Worldwide Research & Development, San Diego, California
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Helen Y. Zou
Pharmacokinetics, Dynamics and Metabolism (S.Y., J.L.L., P.V.) and Oncology Research Unit (H.Y.Z., H.W., T.S.), Pfizer Worldwide Research & Development, San Diego, California
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Hui Wang
Pharmacokinetics, Dynamics and Metabolism (S.Y., J.L.L., P.V.) and Oncology Research Unit (H.Y.Z., H.W., T.S.), Pfizer Worldwide Research & Development, San Diego, California
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Tod Smeal
Pharmacokinetics, Dynamics and Metabolism (S.Y., J.L.L., P.V.) and Oncology Research Unit (H.Y.Z., H.W., T.S.), Pfizer Worldwide Research & Development, San Diego, California
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Paolo Vicini
Pharmacokinetics, Dynamics and Metabolism (S.Y., J.L.L., P.V.) and Oncology Research Unit (H.Y.Z., H.W., T.S.), Pfizer Worldwide Research & Development, San Diego, California
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Journal of Pharmacology and Experimental Therapeutics: 351 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 351, Issue 1
1 Oct 2014
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Research ArticleDrug Discovery and Translational Medicine

Translational PKPD Modeling of a Novel ALK Inhibitor

Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
Journal of Pharmacology and Experimental Therapeutics October 1, 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

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Research ArticleDrug Discovery and Translational Medicine

Translational PKPD Modeling of a Novel ALK Inhibitor

Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
Journal of Pharmacology and Experimental Therapeutics October 1, 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141
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