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Index by author

October 01, 2014; Volume 351,Issue 1

A

  1. Abdel-Rahman, Abdel A.

    1. Neuronal Nitric Oxide Synthase–Dependent Elevation in Adiponectin in the Rostral Ventrolateral Medulla Underlies G Protein–Coupled Receptor 18–Mediated Hypotension in Conscious Rats
      Anusha Penumarti and Abdel A. Abdel-Rahman
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 44-53; DOI: https://doi.org/10.1124/jpet.114.216036

  2. Al-Zaubai, Nuha

    1. Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
      Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

  3. Amella, Carol A.

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

  4. Antony, Veena

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  5. Ayroldi, Emira

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

B

  1. Banks, William A.

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

  2. Beaudry, Rhys

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  3. Bee, Lucy A.

    1. Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
      Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028

  4. Bi, Yi-an

    1. Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model
      Manthena V. Varma, Yi-an Bi, Emi Kimoto and Jian Lin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 214-223; DOI: https://doi.org/10.1124/jpet.114.215970

  5. Brancaleone, Vincenzo

    1. Annexin A1 Mediates Hydrogen Sulfide Properties in the Control of Inflammation
      Vincenzo Brancaleone, Emma Mitidieri, Roderick J. Flower, Giuseppe Cirino and Mauro Perretti
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 96-104; DOI: https://doi.org/10.1124/jpet.114.217034

C

  1. Cai, Guo-Qiang

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  2. Camargo, Simone M. R.

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  3. Carcolé, Mireia

    1. Treatment with a Heme Oxygenase 1 Inducer Enhances the Antinociceptive Effects of µ-Opioid, δ-Opioid, and Cannabinoid 2 Receptors during Inflammatory Pain
      Mireia Carcolé, Sílvia Castany, Sergi Leánez and Olga Pol
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 224-232; DOI: https://doi.org/10.1124/jpet.114.215681

  4. Carmack, Terry L.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  5. Castany, Sílvia

    1. Treatment with a Heme Oxygenase 1 Inducer Enhances the Antinociceptive Effects of µ-Opioid, δ-Opioid, and Cannabinoid 2 Receptors during Inflammatory Pain
      Mireia Carcolé, Sílvia Castany, Sergi Leánez and Olga Pol
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 224-232; DOI: https://doi.org/10.1124/jpet.114.215681

  6. Chappell, A. S.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  7. Che, Pulin

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  8. Chen, Yan

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  9. Cheng, Xingguo

    1. Decreased Bile-Acid Synthesis in Livers of Hepatocyte-Conditional NADPH–Cytochrome P450 Reductase–Null Mice Results in Increased Bile Acids in Serum
      Xingguo Cheng, Youcai Zhang and Curtis D. Klaassen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 105-113; DOI: https://doi.org/10.1124/jpet.114.216796

  10. Cirino, Giuseppe

    1. Annexin A1 Mediates Hydrogen Sulfide Properties in the Control of Inflammation
      Vincenzo Brancaleone, Emma Mitidieri, Roderick J. Flower, Giuseppe Cirino and Mauro Perretti
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 96-104; DOI: https://doi.org/10.1124/jpet.114.217034

  11. Cleator, John H.

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  12. Colowick, Nancy E.

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  13. Constantinides, Panayiotis P.

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

  14. Cordy, Benjamin J.

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

D

  1. Decker, Michael W.

    1. The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
      Danhui Zhang, Matthew McGregor, Michael W. Decker and Maryka Quik
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 25-32; DOI: https://doi.org/10.1124/jpet.114.216283

  2. Delfino, Domenico V.

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  3. Desai, Leena P.

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  4. Dickenson, Anthony

    1. Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
      Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028

  5. Ding, Qiang

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  6. Duvernay, Matthew T.

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

F

  1. Falcone, Joseph A.

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

  2. Fergason-Cantrell, Emily A.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  3. Fierabracci, Alessandra

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  4. Flower, Roderick J.

    1. Annexin A1 Mediates Hydrogen Sulfide Properties in the Control of Inflammation
      Vincenzo Brancaleone, Emma Mitidieri, Roderick J. Flower, Giuseppe Cirino and Mauro Perretti
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 96-104; DOI: https://doi.org/10.1124/jpet.114.217034

  5. Fukasawa, Masayoshi

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

G

  1. Gardinier, K.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  2. Gernert, D. L.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  3. Gleason, S. D.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  4. Götze, Oliver

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  5. Green, Caroline L.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  6. Greenwood-Van Meerveld, Beverley

    1. Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
      Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028

H

  1. Hahn, P. J.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  2. Hamm, Heidi E.

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  3. Han, Xiaosi

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  4. Harrell, Frank E.

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  5. Hashimoto, Terumasa

    1. Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse
      Koji Nobe, Yasuhiro Takenouchi, Keizo Kasono, Terumasa Hashimoto and Kazuo Honda
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 77-86; DOI: https://doi.org/10.1124/jpet.114.216747

  6. Hegde, Sharath S.

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  7. Hobbs, J.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  8. Holinstat, Michael

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  9. Holt, Andrew

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  10. Honda, Kazuo

    1. Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse
      Koji Nobe, Yasuhiro Takenouchi, Keizo Kasono, Terumasa Hashimoto and Kazuo Honda
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 77-86; DOI: https://doi.org/10.1124/jpet.114.216747

  11. Hu, Meng

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  12. Huang, Shu Kuei

    1. Cyclooxygenase 2 Inhibitor Celecoxib Inhibits Glutamate Release by Attenuating the PGE2/EP2 Pathway in Rat Cerebral Cortex Endings
      Tzu-Yu Lin, Cheng-Wei Lu, Chia-Chuan Wang, Shu Kuei Huang and Su-Jane Wang
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 134-145; DOI: https://doi.org/10.1124/jpet.114.217372

  13. Hudson, Alan L.

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  14. Hudson, Willie J.

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  15. Huggel, Katja

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  16. Hughes, Adam D.

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

I

  1. Iida, Manami

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  2. Ishii-Watabe, Akiko

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  3. Iwamura, Tomokatsu

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

J

  1. Jasper, Jeffrey R.

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  2. Jin, X.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  3. Johnstone, Cameron N.

    1. Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
      Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

K

  1. Kabanov, Alexander V.

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

  2. Kainoh, Mie

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  3. Kasono, Keizo

    1. Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse
      Koji Nobe, Yasuhiro Takenouchi, Keizo Kasono, Terumasa Hashimoto and Kazuo Honda
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 77-86; DOI: https://doi.org/10.1124/jpet.114.216747

  4. Kawahigashi, Yumi

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  5. Kawai, Koji

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  6. Kerr, Paul M.

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  7. Kimoto, Emi

    1. Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model
      Manthena V. Varma, Yi-an Bi, Emi Kimoto and Jian Lin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 214-223; DOI: https://doi.org/10.1124/jpet.114.215970

  8. Kimura, Yuka

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  9. Klaassen, Curtis D.

    1. Decreased Bile-Acid Synthesis in Livers of Hepatocyte-Conditional NADPH–Cytochrome P450 Reductase–Null Mice Results in Increased Bile Acids in Serum
      Xingguo Cheng, Youcai Zhang and Curtis D. Klaassen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 105-113; DOI: https://doi.org/10.1124/jpet.114.216796

  10. Kondoh, Masuo

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  11. Kumagai, Hiroki

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  12. Kuniyasu, Hiroki

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

L

  1. Lalies, Margaret D.

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  2. Lam, Justine L.

    1. Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
      Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

  3. Leánez, Sergi

    1. Treatment with a Heme Oxygenase 1 Inducer Enhances the Antinociceptive Effects of µ-Opioid, δ-Opioid, and Cannabinoid 2 Receptors during Inflammatory Pain
      Mireia Carcolé, Sílvia Castany, Sergi Leánez and Olga Pol
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 224-232; DOI: https://doi.org/10.1124/jpet.114.215681

  4. Lee, Sang-Min

    1. Dopamine D1 Receptor Signaling: Does GαQ–Phospholipase C Actually Play a Role?
      Sang-Min Lee, Yang Yang and Richard B. Mailman
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 9-17; DOI: https://doi.org/10.1124/jpet.114.214411

  5. Lee, Tae-Weon

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  6. Leong, May May

    1. Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
      Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

  7. Lever, John R.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  8. Lever, Susan Z.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  9. Li, John

    1. Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
      Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

  10. Li, Xiangru

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  11. Liberati, Anna Marina

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  12. Light, Peter E.

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  13. Lin, Jian

    1. Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model
      Manthena V. Varma, Yi-an Bi, Emi Kimoto and Jian Lin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 214-223; DOI: https://doi.org/10.1124/jpet.114.215970

  14. Lin, Tzu-Yu

    1. Cyclooxygenase 2 Inhibitor Celecoxib Inhibits Glutamate Release by Attenuating the PGE2/EP2 Pathway in Rat Cerebral Cortex Endings
      Tzu-Yu Lin, Cheng-Wei Lu, Chia-Chuan Wang, Shu Kuei Huang and Su-Jane Wang
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 134-145; DOI: https://doi.org/10.1124/jpet.114.217372

  15. Liu, Gang

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  16. Liu, Rui-ming

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  17. Lu, Cheng-Wei

    1. Cyclooxygenase 2 Inhibitor Celecoxib Inhibits Glutamate Release by Attenuating the PGE2/EP2 Pathway in Rat Cerebral Cortex Endings
      Tzu-Yu Lin, Cheng-Wei Lu, Chia-Chuan Wang, Shu Kuei Huang and Su-Jane Wang
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 134-145; DOI: https://doi.org/10.1124/jpet.114.217372

  18. Luckhardt, Tracy

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  19. Lunn, Stephanie E.

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

M

  1. Mailman, Richard B.

    1. Dopamine D1 Receptor Signaling: Does GαQ–Phospholipase C Actually Play a Role?
      Sang-Min Lee, Yang Yang and Richard B. Mailman
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 9-17; DOI: https://doi.org/10.1124/jpet.114.214411

  2. Mammen, Mathai

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  3. Mariotta, Luca

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  4. Martelli, Maria Paola

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  5. Martin, William J.

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  6. Mattheolabakis, George

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

  7. McGregor, Matthew

    1. The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
      Danhui Zhang, Matthew McGregor, Michael W. Decker and Maryka Quik
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 25-32; DOI: https://doi.org/10.1124/jpet.114.216283

  8. McNamara, Alexander

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  9. Miller, Dennis K.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  10. Mitidieri, Emma

    1. Annexin A1 Mediates Hydrogen Sulfide Properties in the Control of Inflammation
      Vincenzo Brancaleone, Emma Mitidieri, Roderick J. Flower, Giuseppe Cirino and Mauro Perretti
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 96-104; DOI: https://doi.org/10.1124/jpet.114.217034

  11. Mohammadi, Ehsan

    1. Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
      Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028

  12. Mortell, William G.

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

  13. Motulsky, Harvey J.

    1. Common Misconceptions about Data Analysis and Statistics
      Harvey J. Motulsky
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 200-205; DOI: https://doi.org/10.1124/jpet.114.219170

N

  1. Nakaki, Junko

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  2. Narang, Deepak

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  3. Nitta, Aiko

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  4. Nobe, Koji

    1. Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse
      Koji Nobe, Yasuhiro Takenouchi, Keizo Kasono, Terumasa Hashimoto and Kazuo Honda
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 77-86; DOI: https://doi.org/10.1124/jpet.114.216747

O

  1. O’Reilly, Philip J.

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  2. Okazaki, Seiji

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

P

  1. Penumarti, Anusha

    1. Neuronal Nitric Oxide Synthase–Dependent Elevation in Adiponectin in the Rostral Ventrolateral Medulla Underlies G Protein–Coupled Receptor 18–Mediated Hypotension in Conscious Rats
      Anusha Penumarti and Abdel A. Abdel-Rahman
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 44-53; DOI: https://doi.org/10.1124/jpet.114.216036

  2. Perretti, Mauro

    1. Annexin A1 Mediates Hydrogen Sulfide Properties in the Control of Inflammation
      Vincenzo Brancaleone, Emma Mitidieri, Roderick J. Flower, Giuseppe Cirino and Mauro Perretti
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 96-104; DOI: https://doi.org/10.1124/jpet.114.217034

  3. Pietra, Claudio

    1. Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
      Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028

  4. Ping, X.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  5. Plane, Frances

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  6. Pol, Olga

    1. Treatment with a Heme Oxygenase 1 Inducer Enhances the Antinociceptive Effects of µ-Opioid, δ-Opioid, and Cannabinoid 2 Receptors during Inflammatory Pain
      Mireia Carcolé, Sílvia Castany, Sergi Leánez and Olga Pol
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 224-232; DOI: https://doi.org/10.1124/jpet.114.215681

  7. Pozzesi, Nicola

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  8. Pulido-Rios, M. Teresa

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

Q

  1. Quik, Maryka

    1. The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
      Danhui Zhang, Matthew McGregor, Michael W. Decker and Maryka Quik
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 25-32; DOI: https://doi.org/10.1124/jpet.114.216283

R

  1. Ramadan, Tamara

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  2. Riccardi, Carlo

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  3. Richards, Robert

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

  4. Rigas, Basil

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

  5. Rizzacasa, Mark

    1. Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
      Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

S

  1. Sakami, Satoshi

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  2. Salameh, Therese S.

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

  3. Sato, Mikiya

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  4. Schank, Jesse R.

    1. The Neurokinin-1 Receptor in Addictive Processes
      Jesse R. Schank
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 2-8; DOI: https://doi.org/10.1124/jpet.113.210799

  5. Sekiya, Yumiko

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  6. Sher, E.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  7. Siegal, Gene P.

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  8. Sigurdson, Julie

    1. Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
      Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

  9. Sims, J. R.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  10. Singer, Dustin

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  11. Smeal, Tod

    1. Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
      Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

  12. Smith, J. L.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  13. Song, Yanna

    1. Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
      John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616

  14. Steinfeld, Tod

    1. Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
      Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

  15. Stewart, Alastair G.

    1. Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
      Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

  16. Sun, Yu

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

T

  1. Tada, Minoru

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  2. Takahashi, Takehiro

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  3. Takenouchi, Yasuhiro

    1. Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse
      Koji Nobe, Yasuhiro Takenouchi, Keizo Kasono, Terumasa Hashimoto and Kazuo Honda
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 77-86; DOI: https://doi.org/10.1124/jpet.114.216747

  4. Thannickal, Victor J.

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  5. Thuy, Trinh Thy

    1. Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
      Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

  6. Tyler, Karl

    1. Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
      Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028

U

  1. Uno, Tadayuki

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

V

  1. Valli, S. N.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  2. Varma, Manthena V.

    1. Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model
      Manthena V. Varma, Yi-an Bi, Emi Kimoto and Jian Lin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 214-223; DOI: https://doi.org/10.1124/jpet.114.215970

  3. Verrey, François

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

  4. Vicini, Paolo

    1. Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
      Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

  5. Vuille-dit-Bille, Raphael N.

    1. The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
      Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317

W

  1. Wang, Chia-Chuan

    1. Cyclooxygenase 2 Inhibitor Celecoxib Inhibits Glutamate Release by Attenuating the PGE2/EP2 Pathway in Rat Cerebral Cortex Endings
      Tzu-Yu Lin, Cheng-Wei Lu, Chia-Chuan Wang, Shu Kuei Huang and Su-Jane Wang
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 134-145; DOI: https://doi.org/10.1124/jpet.114.217372

  2. Wang, Hui

    1. Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
      Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

  3. Wang, Su-Jane

    1. Cyclooxygenase 2 Inhibitor Celecoxib Inhibits Glutamate Release by Attenuating the PGE2/EP2 Pathway in Rat Cerebral Cortex Endings
      Tzu-Yu Lin, Cheng-Wei Lu, Chia-Chuan Wang, Shu Kuei Huang and Su-Jane Wang
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 134-145; DOI: https://doi.org/10.1124/jpet.114.217372

  4. Watari, Akihiro

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  5. Watkinson, Lisa D.

    1. Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
      John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671

  6. Witkin, J. M.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779

  7. Wong, Chi C.

    1. Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
      George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208

Y

  1. Yagi, Kiyohito

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  2. Yagi, Mai

    1. HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
      Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

  3. Yamashita, Taku

    1. Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
      Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

  4. Yamazaki, Shinji

    1. Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
      Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

  5. Yang, Yang

    1. Dopamine D1 Receptor Signaling: Does GαQ–Phospholipase C Actually Play a Role?
      Sang-Min Lee, Yang Yang and Richard B. Mailman
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 9-17; DOI: https://doi.org/10.1124/jpet.114.214411

  6. Yi, Xiang

    1. Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
      Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705

Z

  1. Zhang, Danhui

    1. The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
      Danhui Zhang, Matthew McGregor, Michael W. Decker and Maryka Quik
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 25-32; DOI: https://doi.org/10.1124/jpet.114.216283

  2. Zhang, Youcai

    1. Decreased Bile-Acid Synthesis in Livers of Hepatocyte-Conditional NADPH–Cytochrome P450 Reductase–Null Mice Results in Increased Bile Acids in Serum
      Xingguo Cheng, Youcai Zhang and Curtis D. Klaassen
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 105-113; DOI: https://doi.org/10.1124/jpet.114.216796

  3. Zhou, Yong

    1. Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
      Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044

  4. Zou, Helen Y.

    1. Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
      Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

  5. Zwart, R.

    1. Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
      R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
      Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779
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