Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

October 01, 2014; Volume 351,Issue 1

Highlighted Papers

  • You have access
    Effect of α7 Nicotinic Receptor Agonist on L-Dopa–Induced Dyskinesias
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 1; DOI: https://doi.org/10.1124/jpet.114.1014HI
  • You have access
    Pegylation Prevents Phospho-Ibuprofen Hydrolysis
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 1; DOI: https://doi.org/10.1124/jpet.114.1014HIa
  • You have access
    Therapeutic Targeting of Src Kinase in Pulmonary Fibrosis
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 1; DOI: https://doi.org/10.1124/jpet.114.1014HIb
  • You have access
    Pharmacology of GSK-961081, an Inhaled Muscarinic Antagonist/β2 Agonist
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 1; DOI: https://doi.org/10.1124/jpet.114.1014HIc

Commentary

  • You have access
    Common Misconceptions about Data Analysis and Statistics
    Harvey J. Motulsky
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 200-205; DOI: https://doi.org/10.1124/jpet.114.219170

Minireviews

  • You have access
    The Neurokinin-1 Receptor in Addictive Processes
    Jesse R. Schank
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 2-8; DOI: https://doi.org/10.1124/jpet.113.210799
  • You have access
    Dopamine D1 Receptor Signaling: Does GαQ–Phospholipase C Actually Play a Role?
    Sang-Min Lee, Yang Yang and Richard B. Mailman
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 9-17; DOI: https://doi.org/10.1124/jpet.114.214411
  • You have access
    Pharmacological Modulation of Caspase-8 in Thymus-Related Medical Conditions
    Nicola Pozzesi, Alessandra Fierabracci, Trinh Thy Thuy, Maria Paola Martelli, Anna Marina Liberati, Emira Ayroldi, Carlo Riccardi and Domenico V. Delfino
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 18-24; DOI: https://doi.org/10.1124/jpet.114.216572

Behavioral Pharmacology

  • You have access
    The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
    Danhui Zhang, Matthew McGregor, Michael W. Decker and Maryka Quik
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 25-32; DOI: https://doi.org/10.1124/jpet.114.216283
  • You have access
    Relationship between Cerebral Sigma-1 Receptor Occupancy and Attenuation of Cocaine’s Motor Stimulatory Effects in Mice by PD144418
    John R. Lever, Dennis K. Miller, Emily A. Fergason-Cantrell, Caroline L. Green, Lisa D. Watkinson, Terry L. Carmack and Susan Z. Lever
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 153-163; DOI: https://doi.org/10.1124/jpet.114.216671
  • You have access
    Treatment with a Heme Oxygenase 1 Inducer Enhances the Antinociceptive Effects of µ-Opioid, δ-Opioid, and Cannabinoid 2 Receptors during Inflammatory Pain
    Mireia Carcolé, Sílvia Castany, Sergi Leánez and Olga Pol
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 224-232; DOI: https://doi.org/10.1124/jpet.114.215681

Cardiovascular

  • You have access
    Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
    John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell and Heidi E. Hamm
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 33-43; DOI: https://doi.org/10.1124/jpet.114.215616
  • You have access
    Neuronal Nitric Oxide Synthase–Dependent Elevation in Adiponectin in the Rostral Ventrolateral Medulla Underlies G Protein–Coupled Receptor 18–Mediated Hypotension in Conscious Rats
    Anusha Penumarti and Abdel A. Abdel-Rahman
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 44-53; DOI: https://doi.org/10.1124/jpet.114.216036
  • You have access
    Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions
    Deepak Narang, Paul M. Kerr, Stephanie E. Lunn, Rhys Beaudry, Julie Sigurdson, Margaret D. Lalies, Alan L. Hudson, Peter E. Light, Andrew Holt and Frances Plane
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 164-171; DOI: https://doi.org/10.1124/jpet.114.216523

Cellular and Molecular

  • You have access
    Resolvin D2 Supports MCF-7 Cell Proliferation via Activation of Estrogen Receptor
    Nuha Al-Zaubai, Cameron N. Johnstone, May May Leong, John Li, Mark Rizzacasa and Alastair G. Stewart
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 172-180; DOI: https://doi.org/10.1124/jpet.114.214403

Chemotherapy, Antibiotics, and Gene Therapy

  • You have access
    Development of an Anti–Claudin-3 and -4 Bispecific Monoclonal Antibody for Cancer Diagnosis and Therapy
    Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi and Masuo Kondoh
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 206-213; DOI: https://doi.org/10.1124/jpet.114.216911

Drug Discovery and Translational Medicine

  • You have access
    Intranasal Administration as a Route for Drug Delivery to the Brain: Evidence for a Unique Pathway for Albumin
    Joseph A. Falcone, Therese S. Salameh, Xiang Yi, Benjamin J. Cordy, William G. Mortell, Alexander V. Kabanov and William A. Banks
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 54-60; DOI: https://doi.org/10.1124/jpet.114.216705
  • You have access
    Pegylation Improves the Pharmacokinetics and Bioavailability of Small-Molecule Drugs Hydrolyzable by Esterases: A Study of Phospho-Ibuprofen
    George Mattheolabakis, Chi C. Wong, Yu Sun, Carol A. Amella, Robert Richards, Panayiotis P. Constantinides and Basil Rigas
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 61-66; DOI: https://doi.org/10.1124/jpet.114.217208
  • You have access
    Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Anaplastic Lymphoma Kinase and c-Ros Oncogene 1
    Shinji Yamazaki, Justine L. Lam, Helen Y. Zou, Hui Wang, Tod Smeal and Paolo Vicini
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 67-76; DOI: https://doi.org/10.1124/jpet.114.217141

Endocrine and Diabetes

  • You have access
    Two Types of Overcontraction Are Involved in Intrarenal Artery Dysfunction in Type II Diabetic Mouse
    Koji Nobe, Yasuhiro Takenouchi, Keizo Kasono, Terumasa Hashimoto and Kazuo Honda
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 77-86; DOI: https://doi.org/10.1124/jpet.114.216747
  • You have access
    HIS-388, a Novel Orally Active and Long-Acting 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Ameliorates Insulin Sensitivity and Glucose Intolerance in Diet-Induced Obesity and Nongenetic Type 2 Diabetic Murine Models
    Seiji Okazaki, Takehiro Takahashi, Tomokatsu Iwamura, Junko Nakaki, Yumiko Sekiya, Mai Yagi, Hiroki Kumagai, Mikiya Sato, Satoshi Sakami, Aiko Nitta, Koji Kawai and Mie Kainoh
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 181-189; DOI: https://doi.org/10.1124/jpet.114.216556

Gastrointestinal, Hepatic, Pulmonary, and Renal

  • You have access
    Therapeutic Targeting of Src Kinase in Myofibroblast Differentiation and Pulmonary Fibrosis
    Meng Hu, Pulin Che, Xiaosi Han, Guo-Qiang Cai, Gang Liu, Veena Antony, Tracy Luckhardt, Gene P. Siegal, Yong Zhou, Rui-ming Liu, Leena P. Desai, Philip J. O’Reilly, Victor J. Thannickal and Qiang Ding
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 87-95; DOI: https://doi.org/10.1124/jpet.114.216044
  • You have access
    Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β2-Adrenoceptor Agonist Properties
    Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin, M. Teresa Pulido-Rios and Mathai Mammen
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 190-199; DOI: https://doi.org/10.1124/jpet.114.216861

Inflammation, Immunopharmacology, and Asthma

  • You have access
    Annexin A1 Mediates Hydrogen Sulfide Properties in the Control of Inflammation
    Vincenzo Brancaleone, Emma Mitidieri, Roderick J. Flower, Giuseppe Cirino and Mauro Perretti
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 96-104; DOI: https://doi.org/10.1124/jpet.114.217034

Metabolism, Transport, and Pharmacogenomics

  • You have access
    Decreased Bile-Acid Synthesis in Livers of Hepatocyte-Conditional NADPH–Cytochrome P450 Reductase–Null Mice Results in Increased Bile Acids in Serum
    Xingguo Cheng, Youcai Zhang and Curtis D. Klaassen
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 105-113; DOI: https://doi.org/10.1124/jpet.114.216796
  • You have access
    The Molecular Mechanism of Intestinal Levodopa Absorption and Its Possible Implications for the Treatment of Parkinson’s Disease
    Simone M. R. Camargo, Raphael N. Vuille-dit-Bille, Luca Mariotta, Tamara Ramadan, Katja Huggel, Dustin Singer, Oliver Götze and François Verrey
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 114-123; DOI: https://doi.org/10.1124/jpet.114.216317
  • You have access
    Quantitative Prediction of Transporter- and Enzyme-Mediated Clinical Drug-Drug Interactions of Organic Anion-Transporting Polypeptide 1B1 Substrates Using a Mechanistic Net-Effect Model
    Manthena V. Varma, Yi-an Bi, Emi Kimoto and Jian Lin
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 214-223; DOI: https://doi.org/10.1124/jpet.114.215970

Neuropharmacology

  • You have access
    Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models
    R. Zwart, E. Sher, X. Ping, X. Jin, J. R. Sims, A. S. Chappell, S. D. Gleason, P. J. Hahn, K. Gardinier, D. L. Gernert, J. Hobbs, J. L. Smith, S. N. Valli and J. M. Witkin
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 124-133; DOI: https://doi.org/10.1124/jpet.114.212779
  • You have access
    Cyclooxygenase 2 Inhibitor Celecoxib Inhibits Glutamate Release by Attenuating the PGE2/EP2 Pathway in Rat Cerebral Cortex Endings
    Tzu-Yu Lin, Cheng-Wei Lu, Chia-Chuan Wang, Shu Kuei Huang and Su-Jane Wang
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 134-145; DOI: https://doi.org/10.1124/jpet.114.217372
  • You have access
    Synergistic Effect of 5-Hydroxytryptamine 3 and Neurokinin 1 Receptor Antagonism in Rodent Models of Somatic and Visceral Pain
    Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Karl Tyler, Claudio Pietra, Lucy A. Bee and Anthony Dickenson
    Journal of Pharmacology and Experimental Therapeutics October 2014, 351 (1) 146-152; DOI: https://doi.org/10.1124/jpet.114.216028
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 351 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 351, Issue 1
1 Oct 2014
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Highlighted Papers
  • Commentary
  • Minireviews
  • Behavioral Pharmacology
  • Cardiovascular
  • Cellular and Molecular
  • Chemotherapy, Antibiotics, and Gene Therapy
  • Drug Discovery and Translational Medicine
  • Endocrine and Diabetes
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Inflammation, Immunopharmacology, and Asthma
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
  • Most Cited
  • Most Read
Loading
  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics