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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Astragaloside IV Ameliorates Renal Fibrosis via the Inhibition of Mitogen-Activated Protein Kinases and Antiapoptosis In Vivo and In Vitro

Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou and Zhaohui Ni
Journal of Pharmacology and Experimental Therapeutics September 2014, 350 (3) 552-562; DOI: https://doi.org/10.1124/jpet.114.214205
Weijia Xu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Xinghua Shao
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Lei Tian
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Leyi Gu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Minfang Zhang
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Qin Wang
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Bei Wu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Ling Wang
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Jufang Yao
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Xiaoping Xu
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Shan Mou
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Zhaohui Ni
Department of Nephrology, Molecular Cell Laboratory for Kidney Disease (W.X., X.S., L.T., L.G., M.Z., Q.W., B.W., L.W., S.M., Z.N.), Animal Centre (J.Y.), and Department of Biochemical Laboratory (X.X.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Journal of Pharmacology and Experimental Therapeutics: 350 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 350, Issue 3
1 Sep 2014
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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Astragaloside IV Inhibits Renal Fibrosis

Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou and Zhaohui Ni
Journal of Pharmacology and Experimental Therapeutics September 1, 2014, 350 (3) 552-562; DOI: https://doi.org/10.1124/jpet.114.214205

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Research ArticleGastrointestinal, Hepatic, Pulmonary, and Renal

Astragaloside IV Inhibits Renal Fibrosis

Weijia Xu, Xinghua Shao, Lei Tian, Leyi Gu, Minfang Zhang, Qin Wang, Bei Wu, Ling Wang, Jufang Yao, Xiaoping Xu, Shan Mou and Zhaohui Ni
Journal of Pharmacology and Experimental Therapeutics September 1, 2014, 350 (3) 552-562; DOI: https://doi.org/10.1124/jpet.114.214205
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