Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering

Tracy Mitchell; Ginger Chao; Doree Sitkoff; Fred Lo; Hossain Monshizadegan; Daniel Meyers; Simon Low; Katie Russo; Rose DiBella; Fabienne Denhez; Mian Gao; Joseph Myers; Gerald Duke; Mark Witmer; Bowman Miao; Siew P. Ho; Javed Khan; Rex A. Parker

doi:10.1124/jpet.114.214221

Research ArticleDrug Discovery and Translational Medicine

Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering

Tracy Mitchell, Ginger Chao, Doree Sitkoff, Fred Lo, Hossain Monshizadegan, Daniel Meyers, Simon Low, Katie Russo, Rose DiBella, Fabienne Denhez, Mian Gao, Joseph Myers, Gerald Duke, Mark Witmer, Bowman Miao, Siew P. Ho, Javed Khan and Rex A. Parker

Journal of Pharmacology and Experimental Therapeutics August 2014, 350 (2) 412-424; DOI: https://doi.org/10.1124/jpet.114.214221

Tracy Mitchell

Molecular Discovery Technologies (T.M., G.C., D.S., S.L., K.R., R.D., F.D., M.G., J.M., G.D., M.W., J.K.), Applied Genomics (S.P.H.), and Cardiovascular Discovery Biology (F.L., H.M., D.M., B.M., R.A.P.), Bristol-Myers Squibb Research and Development, Princeton, New Jersey

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Ginger Chao

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Doree Sitkoff

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Fred Lo

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Hossain Monshizadegan

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Daniel Meyers

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Simon Low

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Katie Russo

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Rose DiBella

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Fabienne Denhez

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Mian Gao

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Joseph Myers

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Gerald Duke

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Mark Witmer

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Bowman Miao

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Siew P. Ho

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Javed Khan

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Rex A. Parker

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Journal of Pharmacology and Experimental Therapeutics

Vol. 350, Issue 2

1 Aug 2014

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Research ArticleDrug Discovery and Translational Medicine