3,3′-Diindolylmethane Ameliorates Experimental Autoimmune Encephalomyelitis by Promoting Cell Cycle Arrest and Apoptosis in Activated T Cells through MicroRNA Signaling Pathways

Michael Rouse; Roshni Rao; Mitzi Nagarkatti; Prakash S. Nagarkatti

doi:10.1124/jpet.114.214742

Research ArticleDrug Discovery and Translational Medicine

3,3′-Diindolylmethane Ameliorates Experimental Autoimmune Encephalomyelitis by Promoting Cell Cycle Arrest and Apoptosis in Activated T Cells through MicroRNA Signaling Pathways

Michael Rouse, Roshni Rao, Mitzi Nagarkatti and Prakash S. Nagarkatti

Journal of Pharmacology and Experimental Therapeutics August 2014, 350 (2) 341-352; DOI: https://doi.org/10.1124/jpet.114.214742

Michael Rouse

Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina

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Roshni Rao

Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina

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Mitzi Nagarkatti

Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina

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Prakash S. Nagarkatti

Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina

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Journal of Pharmacology and Experimental Therapeutics

Vol. 350, Issue 2

1 Aug 2014

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Research ArticleDrug Discovery and Translational Medicine