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Research ArticleDrug Discovery and Translational Medicine

3,3′-Diindolylmethane Ameliorates Experimental Autoimmune Encephalomyelitis by Promoting Cell Cycle Arrest and Apoptosis in Activated T Cells through MicroRNA Signaling Pathways

Michael Rouse, Roshni Rao, Mitzi Nagarkatti and Prakash S. Nagarkatti
Journal of Pharmacology and Experimental Therapeutics August 2014, 350 (2) 341-352; DOI: https://doi.org/10.1124/jpet.114.214742
Michael Rouse
Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina
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Roshni Rao
Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina
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Mitzi Nagarkatti
Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina
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Prakash S. Nagarkatti
Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina
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Article Information

vol. 350 no. 2 341-352
DOI 
https://doi.org/10.1124/jpet.114.214742
PubMed 
24898268

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received March 31, 2014
  • Accepted June 3, 2014
  • Published online June 26, 2014.

Article Versions

  • Earlier version (June 4, 2014 - 12:01).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Michael Rouse,
  2. Roshni Rao,
  3. Mitzi Nagarkatti, and
  4. Prakash S. Nagarkatti
  1. Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South Carolina
  1. Address correspondence to:
    Dr. Prakash S. Nagarkatti, 202 Osborne Administration Building, University of South Carolina, Columbia, SC 29208. E-mail: prakash{at}mailbox.sc.edu
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Journal of Pharmacology and Experimental Therapeutics: 350 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 350, Issue 2
1 Aug 2014
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Research ArticleDrug Discovery and Translational Medicine

DIM Ameliorates EAE by miRNA Regulation

Michael Rouse, Roshni Rao, Mitzi Nagarkatti and Prakash S. Nagarkatti
Journal of Pharmacology and Experimental Therapeutics August 1, 2014, 350 (2) 341-352; DOI: https://doi.org/10.1124/jpet.114.214742

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Research ArticleDrug Discovery and Translational Medicine

DIM Ameliorates EAE by miRNA Regulation

Michael Rouse, Roshni Rao, Mitzi Nagarkatti and Prakash S. Nagarkatti
Journal of Pharmacology and Experimental Therapeutics August 1, 2014, 350 (2) 341-352; DOI: https://doi.org/10.1124/jpet.114.214742
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