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Research ArticleInflammation, Immunopharmacology, and Asthma

The In Vitro Pharmacology of GS-5759, A Novel Bifunctional Phosphodiesterase 4 Inhibitor and Long Acting β2-Adrenoceptor Agonist

Stacey L. Tannheimer, Eric A. Sorensen, Zhi-Hua Cui, Musong Kim, Leena Patel, William R. Baker, Gary B. Phillips, Clifford D. Wright and Michael Salmon
Journal of Pharmacology and Experimental Therapeutics April 2014, 349 (1) 85-93; DOI: https://doi.org/10.1124/jpet.113.210997
Stacey L. Tannheimer
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Eric A. Sorensen
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Zhi-Hua Cui
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Musong Kim
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Leena Patel
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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William R. Baker
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Gary B. Phillips
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Clifford D. Wright
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Michael Salmon
Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
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Article Information

vol. 349 no. 1 85-93
DOI 
https://doi.org/10.1124/jpet.113.210997
PubMed 
24513870

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 5, 2013
  • Accepted February 7, 2014
  • Published online March 5, 2014.

Article Versions

  • Earlier version (February 10, 2014 - 11:18).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Stacey L. Tannheimer,
  2. Eric A. Sorensen,
  3. Zhi-Hua Cui,
  4. Musong Kim,
  5. Leena Patel,
  6. William R. Baker,
  7. Gary B. Phillips,
  8. Clifford D. Wright, and
  9. Michael Salmon1
  1. Oncology/Inflammation Research (S.L.T., E.A.S., Z-H.C., C.D.W., M.S.), Medicinal Chemistry (M.K., L.P., W.R.B., G.B.P.), Gilead Sciences Inc., Seattle, Washington
  1. Address correspondence to:
    Dr. Stacey Tannheimer, Gilead Sciences, Oncology/Inflammation Research, 199 E. Blaine Street, Seattle, WA 98102. E-mail: stacey.tannheimer{at}gilead.com
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Journal of Pharmacology and Experimental Therapeutics: 349 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 349, Issue 1
1 Apr 2014
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Research ArticleInflammation, Immunopharmacology, and Asthma

In Vitro Pharmacology of GS-5759

Stacey L. Tannheimer, Eric A. Sorensen, Zhi-Hua Cui, Musong Kim, Leena Patel, William R. Baker, Gary B. Phillips, Clifford D. Wright and Michael Salmon
Journal of Pharmacology and Experimental Therapeutics April 1, 2014, 349 (1) 85-93; DOI: https://doi.org/10.1124/jpet.113.210997

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Research ArticleInflammation, Immunopharmacology, and Asthma

In Vitro Pharmacology of GS-5759

Stacey L. Tannheimer, Eric A. Sorensen, Zhi-Hua Cui, Musong Kim, Leena Patel, William R. Baker, Gary B. Phillips, Clifford D. Wright and Michael Salmon
Journal of Pharmacology and Experimental Therapeutics April 1, 2014, 349 (1) 85-93; DOI: https://doi.org/10.1124/jpet.113.210997
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