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Research ArticleNeuropharmacology

Inhibition of Excitatory Synaptic Transmission in Hippocampal Neurons by Levetiracetam Involves Zn2+-Dependent GABA Type A Receptor–Mediated Presynaptic Modulation

Masahito Wakita, Naoki Kotani, Kyuya Kogure and Norio Akaike
Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 246-259; DOI: https://doi.org/10.1124/jpet.113.208751

Article Information

vol. 348 no. 2 246-259
DOI 
https://doi.org/10.1124/jpet.113.208751
PubMed 
24259680
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 13, 2013
  • Accepted November 19, 2013
  • Published online January 2, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Masahito Wakita,
  2. Naoki Kotani,
  3. Kyuya Kogure, and
  4. Norio Akaike
  1. Research Division for Clinical Pharmacology, Medical Corporation, Jyuryokai, Kumamoto Kinoh Hospital, Kumamoto, Japan (M.W., N.A.); Research Division for Life Science, Kumamoto Health Science University, Kumamoto, Japan (M.W., N.A.); Research Division of Neurophysiology, Kitamoto Hospital, Koshigaya, Japan (N.K., N.A); and Kogure Medical Clinic, Chouseikai Medical Corporation, Fukaya City, Saitama, Japan (K.K.)
  1. Address correspondence to:
    Dr. Norio Akaike, Research Division for Life Sciences, Kumamoto Health Science University, 325 Izumi-machi, Kitaku, Kumamoto, 861–5598, Japan. E-mail: akaike{at}kumamoto-hsu.ac.jp
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Research ArticleNeuropharmacology

Levetiracetam and Glutamatergic Transmission

Masahito Wakita, Naoki Kotani, Kyuya Kogure and Norio Akaike
Journal of Pharmacology and Experimental Therapeutics February 1, 2014, 348 (2) 246-259; DOI: https://doi.org/10.1124/jpet.113.208751
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