Journal of Pharmacology and Experimental Therapeutics: 348 (2)

February 01, 2014; Volume 348,Issue 2

Highlighted Papers

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Aryl Hydrocarbon Receptor Antagonism Attenuates Growth Factor Expression in Rheumatoid Arthritis
Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 216; DOI: https://doi.org/10.1124/jpet.114.0214HI
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Glycemic and Vascular Dysfunction in Caveolin-1 Null Mice
Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 216; DOI: https://doi.org/10.1124/jpet.114.0214HIa
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Phosphoinositide 3-Kinase-δ,γ Inhibitor for Rheumatoid Arthritis
Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 216; DOI: https://doi.org/10.1124/jpet.114.0214HIb
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Modulating Heat Shock Protein 70 Improves Diabetic Neuropathy
Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 216; DOI: https://doi.org/10.1124/jpet.114.0214HIc

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A Double Blind, within Subject Comparison of Spontaneous Opioid Withdrawal from Buprenorphine versus Morphine
D. Andrew Tompkins, Michael T. Smith, Miriam Z. Mintzer, Claudia M. Campbell and Eric C. Strain

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 217-226; DOI: https://doi.org/10.1124/jpet.113.209478
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Antinociceptive Effects of Central Administration of the Endogenous Cannabinoid Receptor Type 1 Agonist VDPVNFKLLSH-OH [(m)VD-hemopressin(α)], an N-Terminally Extended Hemopressin Peptide
Zheng-lan Han, Quan Fang, Zi-long Wang, Xu-hui Li, Ning Li, Xue-mei Chang, Jia-xin Pan, Hong-zhu Tang and Rui Wang

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 316-323; DOI: https://doi.org/10.1124/jpet.113.209866

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Dissociation of Hyperglycemia from Altered Vascular Contraction and Relaxation Mechanisms in Caveolin-1 Null Mice
Luminita H. Pojoga, Tham M. Yao, Lauren A. Opsasnick, Amanda E. Garza, Ossama M. Reslan, Gail K. Adler, Gordon H. Williams and Raouf A. Khalil

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 260-270; DOI: https://doi.org/10.1124/jpet.113.209189

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Aryl Hydrocarbon Receptor Antagonism Attenuates Growth Factor Expression, Proliferation, and Migration in Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis
Tejas S. Lahoti, Jarod M. Hughes, Ann Kusnadi, Kaarthik John, Bokai Zhu, Iain A. Murray, Krishne Gowda, Jeffrey M. Peters, Shantu G. Amin and Gary H. Perdew

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 236-245; DOI: https://doi.org/10.1124/jpet.113.209726
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Regulation of Death Induction and Chemosensitizing Action of 3-Bromopyruvate in Myeloid Leukemia Cells: Energy Depletion, Oxidative Stress, and Protein Kinase Activity Modulation
Eva Calviño, María Cristina Estañ, Carlos Sánchez-Martín, Rocío Brea, Elena de Blas, María del Carmen Boyano-Adánez, Eduardo Rial and Patricio Aller

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 324-335; DOI: https://doi.org/10.1124/jpet.113.206714
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Mechanism of hERG Channel Block by the Psychoactive Indole Alkaloid Ibogaine
Patrick Thurner, Anna Stary-Weinzinger, Hend Gafar, Vaibhavkumar S. Gawali, Oliver Kudlacek, Juergen Zezula, Karlheinz Hilber, Stefan Boehm, Walter Sandtner and Xaver Koenig

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 346-358; DOI: https://doi.org/10.1124/jpet.113.209643

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Combined Antiproliferative Effects of the Aminoalkylindole WIN55,212-2 and Radiation in Breast Cancer Cells
Sean M. Emery, Moureq R. Alotaibi, Qing Tao, Dana E. Selley, Aron H. Lichtman and David A. Gewirtz

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 293-302; DOI: https://doi.org/10.1124/jpet.113.205120

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Heat Shock Protein 70 Is Necessary to Improve Mitochondrial Bioenergetics and Reverse Diabetic Sensory Neuropathy following KU-32 Therapy
Jiacheng Ma, Kevin L. Farmer, Pan Pan, Michael J. Urban, Huiping Zhao, Brian S. J. Blagg and Rick T. Dobrowsky

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 281-292; DOI: https://doi.org/10.1124/jpet.113.210435

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Mucosal Protective Agents Prevent Exacerbation of NSAID-Induced Small Intestinal Lesions Caused by Antisecretory Drugs in Rats
Hiroshi Satoh, Kikuko Amagase and Koji Takeuchi

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 227-235; DOI: https://doi.org/10.1124/jpet.113.208991

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Novel Phosphoinositide 3-Kinase δ,γ Inhibitor: Potent Anti-Inflammatory Effects and Joint Protection in Models of Rheumatoid Arthritis
David L. Boyle, Hae-Rim Kim, Katharyn Topolewski, Beatrix Bartok and Gary S. Firestein

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 271-280; DOI: https://doi.org/10.1124/jpet.113.205955
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Bronchoprotection by Olodaterol Is Synergistically Enhanced by Tiotropium in a Guinea Pig Model of Allergic Asthma
Marieke Smit, Annet B. Zuidhof, Sophie I. T. Bos, Harm Maarsingh, Reinoud Gosens, Johan Zaagsma and Herman Meurs

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 303-310; DOI: https://doi.org/10.1124/jpet.113.208439

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Absence of P-Glycoprotein Transport in the Pharmacokinetics and Toxicity of the Herbicide Paraquat
Sarah E. Lacher, Julia N. Gremaud, Kasse Skagen, Emily Steed, Rachel Dalton, Kent D. Sugden, Fernando Cardozo-Pelaez, Catherine M. T. Sherwin and Erica L. Woodahl

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 336-345; DOI: https://doi.org/10.1124/jpet.113.209791

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Inhibition of Excitatory Synaptic Transmission in Hippocampal Neurons by Levetiracetam Involves Zn²⁺-Dependent GABA Type A Receptor–Mediated Presynaptic Modulation
Masahito Wakita, Naoki Kotani, Kyuya Kogure and Norio Akaike

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 246-259; DOI: https://doi.org/10.1124/jpet.113.208751
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RETRACTION: Maintained Cocaine Self-Administration Is Determined by Quantal Responses: Implications for the Measurement of Antagonist Potency
Andrew B. Norman, Michael R. Tabet, Mantana K. Norman and Vladimir L. Tsibulsky

Journal of Pharmacology and Experimental Therapeutics February 2014, 348 (2) 311-315; DOI: https://doi.org/10.1124/jpet.113.210690