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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

January 01, 2014; Volume 348,Issue 1

Highlighted Papers

  • You have access
    Modulation of Peripheral μ-Opioid Analgesia by σ1 Receptors
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 1; DOI: https://doi.org/10.1124/jpet.114.0114HI
  • You have access
    A Dopamine Transporter Ligand That Functions as a Cocaine Antagonist
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 1; DOI: https://doi.org/10.1124/jpet.114.0114HIa
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    Benztropine Analogs as Antagonists of Methamphetamine Self-Administration
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 1; DOI: https://doi.org/10.1124/jpet.114.0114HIb
  • You have access
    Inhibition of Renal Potassium Channel Can Cause Diuresis and Natriuresis
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 1; DOI: https://doi.org/10.1124/jpet.114.0114HIc

Perspectives in Pharmacology

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    Analysis of Histamine Receptor Knockout Mice in Models of Inflammation
    Detlef Neumann, Erich H. Schneider and Roland Seifert
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 2-11; DOI: https://doi.org/10.1124/jpet.113.204214

Behavioral Pharmacology

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    Modulation of Peripheral μ-Opioid Analgesia by σ1 Receptors
    Cristina Sánchez-Fernández, Ángeles Montilla-García, Rafael González-Cano, Francisco Rafael Nieto, Lucía Romero, Antonia Artacho-Cordón, Rosa Montes, Begoña Fernández-Pastor, Manuel Merlos, José Manuel Baeyens, José Manuel Entrena and Enrique José Cobos
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 32-45; DOI: https://doi.org/10.1124/jpet.113.208272
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    Pharmacological Characterization of a Dopamine Transporter Ligand That Functions as a Cocaine Antagonist
    Rajeev I. Desai, David K. Grandy, Carl R. Lupica and Jonathan L. Katz
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 106-115; DOI: https://doi.org/10.1124/jpet.113.208538
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    Preclinical Efficacy of N-Substituted Benztropine Analogs as Antagonists of Methamphetamine Self-Administration in Rats
    Takato Hiranita, Stephen J. Kohut, Paul L. Soto, Gianluigi Tanda, Theresa A. Kopajtic and Jonathan L. Katz
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 174-191; DOI: https://doi.org/10.1124/jpet.113.208264

Cardiovascular

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    Stimulation of G Protein–Coupled Bile Acid Receptor Enhances Vascular Endothelial Barrier Function via Activation of Protein Kinase A and Rac1
    Taiki Kida, Keisuke Omori, Masatoshi Hori, Hiroshi Ozaki and Takahisa Murata
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 125-130; DOI: https://doi.org/10.1124/jpet.113.209288
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    Pharmacologic Inhibition of the Renal Outer Medullary Potassium Channel Causes Diuresis and Natriuresis in the Absence of Kaliuresis
    Maria L. Garcia, Birgit T. Priest, Magdalena Alonso-Galicia, Xiaoyan Zhou, John P. Felix, Richard M. Brochu, Timothy Bailey, Brande Thomas-Fowlkes, Jessica Liu, Andrew Swensen, Lee-Yuh Pai, Jianying Xiao, Melba Hernandez, Kimberly Hoagland, Karen Owens, Haifeng Tang, Reynalda K. de Jesus, Sophie Roy, Gregory J. Kaczorowski and Alexander Pasternak
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 153-164; DOI: https://doi.org/10.1124/jpet.113.208603

Cellular and Molecular

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    A Novel and Potent Inhibitor of Dimethylarginine Dimethylaminohydrolase: A Modulator of Cardiovascular Nitric Oxide
    Yohannes T. Ghebremariam, Daniel A. Erlanson and John P. Cooke
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 69-76; DOI: https://doi.org/10.1124/jpet.113.206847
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    Detailed Mechanistic Analysis of Gevokizumab, an Allosteric Anti–IL-1β Antibody with Differential Receptor-Modulating Properties
    Hassan Issafras, John A. Corbin, Ira D. Goldfine and Marina K. Roell
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 202-215; DOI: https://doi.org/10.1124/jpet.113.205443

Drug Discovery and Translational Medicine

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    Chemopreventive Effects of an HDAC2-Selective Inhibitor on Rat Colon Carcinogenesis and APCmin/+ Mouse Intestinal Tumorigenesis
    Durgadevi Ravillah, Altaf Mohammed, Li Qian, Misty Brewer, Yuting Zhang, Laura Biddick, Vernon E. Steele and Chinthalapally V. Rao
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 59-68; DOI: https://doi.org/10.1124/jpet.113.208645
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    Dopamine and Lipophilic Derivates Protect Cardiomyocytes against Cold Preservation Injury
    Christiane Vettel, Maximilia C. Hottenrott, Rahel Spindler, Urs Benck, Peter Schnuelle, Charalambos Tsagogiorgas, Bernhard K. Krämer, Simone Hoeger, Ali El-Armouche, Thomas Wieland and Benito A. Yard
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 77-85; DOI: https://doi.org/10.1124/jpet.113.207001
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    Pharmacokinetic and Pharmacodynamic Properties of GS-9620, a Novel Toll-Like Receptor 7 Agonist, Demonstrate Interferon-Stimulated Gene Induction without Detectable Serum Interferon at Low Oral Doses
    Abigail Fosdick, Jim Zheng, Stefan Pflanz, Christian R. Frey, Joseph Hesselgesser, Randall L. Halcomb, Grushenka Wolfgang and Daniel B. Tumas
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 96-105; DOI: https://doi.org/10.1124/jpet.113.207878
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    Identification of the Antiarrhythmic Drugs Amiodarone and Lorcainide as Potent H3 Histamine Receptor Inverse Agonists
    Andria L. Del Tredici, Jian-Nong Ma, Fabrice Piu and Ethan S. Burstein
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 116-124; DOI: https://doi.org/10.1124/jpet.113.208892
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    Preclinical to Clinical Translation of Tofacitinib, a Janus Kinase Inhibitor, in Rheumatoid Arthritis
    Martin E. Dowty, Michael I. Jesson, Sarbani Ghosh, Jamie Lee, Debra M. Meyer, Sriram Krishnaswami and Nandini Kishore
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 165-173; DOI: https://doi.org/10.1124/jpet.113.209304
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    LLY-2707, A Novel Nonsteroidal Glucocorticoid Antagonist That Reduces Atypical Antipsychotic–Associated Weight Gain in Rats
    Dana K. Sindelar, Mathew W. Carson, Michelle Morin, Janice Shaw, Robert J. Barr, Anne Need, Jesline Alexander-Chacko, Michael Coghlan and Donald R. Gehlert
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 192-201; DOI: https://doi.org/10.1124/jpet.113.205864

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Bradykinin Contracts Rat Urinary Bladder Largely Independently of Phospholipase C
    Carsten Sand and Martin C. Michel
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 25-31; DOI: https://doi.org/10.1124/jpet.113.208025
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    NSAID-Induced Enteropathy: Are the Currently Available Selective COX-2 Inhibitors All the Same?
    Matteo Fornai, Luca Antonioli, Rocchina Colucci, Carolina Pellegrini, Giulio Giustarini, Lara Testai, Alma Martelli, Antuela Matarangasi, Gianfranco Natale, Vincenzo Calderone, Marco Tuccori, Carmelo Scarpignato and Corrado Blandizzi
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 86-95; DOI: https://doi.org/10.1124/jpet.113.207118

Inflammation, Immunopharmacology, and Asthma

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    Induction of Regulator of G-Protein Signaling 2 Expression by Long-Acting β2-Adrenoceptor Agonists and Glucocorticoids in Human Airway Epithelial Cells
    Neil S. Holden, Tresa George, Christopher F. Rider, Ambika Chandrasekhar, Suharsh Shah, Manminder Kaur, Malcolm Johnson, David P. Siderovski, Richard Leigh, Mark A. Giembycz and Robert Newton
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 12-24; DOI: https://doi.org/10.1124/jpet.113.204586

Metabolism, Transport, and Pharmacogenomics

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    Serum- and Glucocorticoid-Regulated Kinase 2 Determines Drug-Activated Pregnane X Receptor to Induce Gluconeogenesis in Human Liver Cells
    Saki Gotoh and Masahiko Negishi
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 131-140; DOI: https://doi.org/10.1124/jpet.113.209379
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    Nitric Oxide and Interleukin-1β Stimulate the Proteasome-Independent Degradation of the Retinoic Acid Hydroxylase CYP2C22 in Primary Rat Hepatocytes
    Choon-myung Lee, Bang-sub Lee, Samuel L. Arnold, Nina Isoherranen and Edward T. Morgan
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 141-152; DOI: https://doi.org/10.1124/jpet.113.209841

Neuropharmacology

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    The Unique α4(+)/(−)α4 Agonist Binding Site in (α4)3(β2)2 Subtype Nicotinic Acetylcholine Receptors Permits Differential Agonist Desensitization Pharmacology versus the (α4)2(β2)3 Subtype
    J. Brek Eaton, Linda M. Lucero, Harrison Stratton, Yongchang Chang, John F. Cooper, Jon M. Lindstrom, Ronald J. Lukas and Paul Whiteaker
    Journal of Pharmacology and Experimental Therapeutics January 2014, 348 (1) 46-58; DOI: https://doi.org/10.1124/jpet.113.208389
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 348 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 348, Issue 1
1 Jan 2014
  • Table of Contents
  • Table of Contents (PDF)
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