Research ArticleChemotherapy, Antibiotics, and Gene Therapy
The Novel Anticancer Agent JNJ-26854165 Induces Cell Death through Inhibition of Cholesterol Transport and Degradation of ABCA1
Richard J. Jones, Dongmin Gu, Chad C. Bjorklund, Isere Kuiatse, Alan T. Remaley, Tarig Bashir, Veronique Vreys and Robert Z. Orlowski
Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 381-392; DOI: https://doi.org/10.1124/jpet.113.204958
Richard J. Jones
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Dongmin Gu
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Chad C. Bjorklund
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Isere Kuiatse
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Alan T. Remaley
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Tarig Bashir
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Veronique Vreys
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)
Robert Z. Orlowski
The Department of Lymphoma and Myeloma (R.J.J., D.G., C.C.B., I.K., R.Z.O.) and the Department of Experimental Therapeutics (R.Z.O.), The University of Texas MD Anderson Cancer Center, Houston, Texas; Lipoprotein Metabolism Section, Cardiopulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland (A.T.R.); and Oncology, Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Beerse, Belgium (T.B., V.V.)

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In this issue
Research ArticleChemotherapy, Antibiotics, and Gene Therapy
JNJ-26854165 Inhibits Cholesterol Transport
Richard J. Jones, Dongmin Gu, Chad C. Bjorklund, Isere Kuiatse, Alan T. Remaley, Tarig Bashir, Veronique Vreys and Robert Z. Orlowski
Journal of Pharmacology and Experimental Therapeutics September 1, 2013, 346 (3) 381-392; DOI: https://doi.org/10.1124/jpet.113.204958
Research ArticleChemotherapy, Antibiotics, and Gene Therapy
JNJ-26854165 Inhibits Cholesterol Transport
Richard J. Jones, Dongmin Gu, Chad C. Bjorklund, Isere Kuiatse, Alan T. Remaley, Tarig Bashir, Veronique Vreys and Robert Z. Orlowski
Journal of Pharmacology and Experimental Therapeutics September 1, 2013, 346 (3) 381-392; DOI: https://doi.org/10.1124/jpet.113.204958
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