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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

September 01, 2013; Volume 346,Issue 3

Highlighted Papers

  • You have access
    Drug-Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HI
  • You have access
    A Compound Selective for I1-Imidazoline Receptors Improves Metabolic Syndrome
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HIa
  • You have access
    JNJ-26854165 Induces Cell Death through Inhibition of Cholesterol Transport
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HIb
  • You have access
    Pharmacokinetics and Pharmacodynamics of the GCP II Inhibitor 2-MPPA
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HIc

Perspectives in Pharmacology

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    Pharmacology at Work for Cardio-Oncology: Ranolazine to Treat Early Cardiotoxicity Induced by Antitumor Drugs
    Giorgio Minotti
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 343-349; DOI: https://doi.org/10.1124/jpet.113.204057

Behavioral Pharmacology

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    Differential Drug–Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073: Implications for Drug Abuse Liability and Pain Therapy
    Lisa K. Brents, Sarah M. Zimmerman, Amanda R. Saffell, Paul L. Prather and William E. Fantegrossi
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 350-361; DOI: https://doi.org/10.1124/jpet.113.206003

Cardiovascular

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    Fetal Rat Hearts Do Not Display Acute Cardiotoxicity in Response to Maternal Doxorubicin Treatment
    Mina Mhallem Gziri, Peter Pokreisz, Rita De Vos, Eric Verbeken, Frédéric Debiève, Luc Mertens, Stefan P. Janssens and Frédéric Amant
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 362-369; DOI: https://doi.org/10.1124/jpet.113.205419
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    A New Pyrroline Compound Selective for I1-Imidazoline Receptors Improves Metabolic Syndrome in Rats
    Lyne Fellmann, Véronique Regnault, Hugues Greney, Vincent Gasparik, Adeline Muscat, Jean-Pierre Max, Luc Gigou, Valérie Oréa, Gérard Chetrite, Anne Pizard, Nathalie Niederhoffer, Claude Julien, Patrick Lacolley, Bruno Fève and Pascal Bousquet
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 370-380; DOI: https://doi.org/10.1124/jpet.113.205328

Chemotherapy, Antibiotics, and Gene Therapy

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    The Novel Anticancer Agent JNJ-26854165 Induces Cell Death through Inhibition of Cholesterol Transport and Degradation of ABCA1
    Richard J. Jones, Dongmin Gu, Chad C. Bjorklund, Isere Kuiatse, Alan T. Remaley, Tarig Bashir, Veronique Vreys and Robert Z. Orlowski
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 381-392; DOI: https://doi.org/10.1124/jpet.113.204958
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    DNA-Damaging Imidazoacridinone C-1311 Induces Autophagy followed by Irreversible Growth Arrest and Senescence in Human Lung Cancer Cells
    Joanna Polewska, Anna Skwarska, Ewa Augustin and Jerzy Konopa
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 393-405; DOI: https://doi.org/10.1124/jpet.113.203851

Drug Discovery and Translational Medicine

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    Pharmacokinetics and Pharmacodynamics of the Glutamate Carboxypeptidase II Inhibitor 2-MPPA Show Prolonged Alleviation of Neuropathic Pain through an Indirect Mechanism
    James J. Vornov, Krystyna M. Wozniak, Ying Wu, Camilo Rojas, Rana Rais and Barbara S. Slusher
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 406-413; DOI: https://doi.org/10.1124/jpet.113.205039
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    Effect of the Mixed Phosphodiesterase 3/4 Inhibitor RPL554 on Human Isolated Bronchial Smooth Muscle Tone
    Luigino Calzetta, Clive P. Page, Domenico Spina, Mario Cazzola, Paola Rogliani, Francesco Facciolo and Maria Gabriella Matera
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 414-423; DOI: https://doi.org/10.1124/jpet.113.204644
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    Anodal Iontophoresis of a Soluble Guanylate Cyclase Stimulator Induces a Sustained Increase in Skin Blood Flow in Rats
    Sylvain Kotzki, Matthieu Roustit, Claire Arnaud, Jean Boutonnat, Sophie Blaise, Diane Godin-Ribuot and Jean-Luc Cracowski
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 424-431; DOI: https://doi.org/10.1124/jpet.113.205484
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    Modeling Tumor Response after Combined Administration of Different Immune-Stimulatory Agents
    Zinnia P. Parra-Guillen, Pedro Berraondo, Benjamin Ribba and Iñaki F. Trocóniz
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 432-442; DOI: https://doi.org/10.1124/jpet.113.206961

Endocrine and Diabetes

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    Chronic Treatment with Novel GPR40 Agonists Improve Whole-Body Glucose Metabolism Based on the Glucose-Dependent Insulin Secretion
    Hirotsugu Tanaka, Shigeru Yoshida, Hiroyuki Oshima, Hideaki Minoura, Kenji Negoro, Takao Yamazaki, Shuichi Sakuda, Fumiyoshi Iwasaki, Tetsuo Matsui and Masayuki Shibasaki
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 443-452; DOI: https://doi.org/10.1124/jpet.113.206466

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Short- and Long-Term Regulation of Intestinal Na+/H+ Exchange Activity Associated with TLR2 Receptor Activation Is Independent of Nuclear Factor-κB Signaling
    José Miguel Cabral, Patrício Soares-da-Silva and Fernando Magro
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 453-464; DOI: https://doi.org/10.1124/jpet.113.204602
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    NLRP3 Inflammasome Knockout Mice Are Protected against Ischemic but Not Cisplatin-Induced Acute Kidney Injury
    Hyun-Jung Kim, Dong Won Lee, Kameswaran Ravichandran, Daniel O. Keys, Ali Akcay, Quocan Nguyen, Zhibin He, Alkesh Jani, Danica Ljubanovic and Charles L. Edelstein
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 465-472; DOI: https://doi.org/10.1124/jpet.113.205732

Inflammation, Immunopharmacology, and Asthma

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    Concurrent Agonism of Adenosine A2B and Glucocorticoid Receptors in Human Airway Epithelial Cells Cooperatively Induces Genes with Anti-Inflammatory Potential: A Novel Approach to Treat Chronic Obstructive Pulmonary Disease
    Stephanie Greer, Cara W. Page, Taruna Joshi, Dong Yan, Robert Newton and Mark A. Giembycz
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 473-485; DOI: https://doi.org/10.1124/jpet.113.206284

Metabolism, Transport, and Pharmacogenomics

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    Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Gene Dosage on Plasma Pharmacokinetics and Brain Accumulation of Dasatinib, Sorafenib, and Sunitinib
    Seng Chuan Tang, Niels de Vries, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 486-494; DOI: https://doi.org/10.1124/jpet.113.205583
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    Substrate-Dependent Inhibition of Human MATE1 by Cationic Ionic Liquids
    Lucy J. Martínez-Guerrero and Stephen H. Wright
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 495-503; DOI: https://doi.org/10.1124/jpet.113.204206
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    Toxicokinetics/Toxicodynamics of γ-Hydroxybutyrate-Ethanol Intoxication: Evaluation of Potential Treatment Strategies
    Bridget L. Morse and Marilyn E. Morris
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 504-513; DOI: https://doi.org/10.1124/jpet.113.206250

Neuropharmacology

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    Pharmacological Characterization of JNJ-40068782, a New Potent, Selective, and Systemically Active Positive Allosteric Modulator of the mGlu2 Receptor and Its Radioligand [3H]JNJ-40068782
    Hilde Lavreysen, Xavier Langlois, Abdel Ahnaou, Wilhelmus Drinkenburg, Paula te Riele, Ilse Biesmans, Ilse Van der Linden, Luc Peeters, Anton Megens, Cindy Wintmolders, Jose Maria Cid, Andrés A. Trabanco, Jose Ignacio Andrés, Frank M. Dautzenberg, Robert Lütjens, Gregor Macdonald and John R. Atack
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 514-527; DOI: https://doi.org/10.1124/jpet.113.204990
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    Long-Lasting Attenuation of Amygdala-Kindled Seizures after Convection-Enhanced Delivery of Botulinum Neurotoxins A and B into the Amygdala in Rats
    Maciej Gasior, Rebecca Tang and Michael A. Rogawski
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 528-534; DOI: https://doi.org/10.1124/jpet.113.205070
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    Stronger Antinociceptive Efficacy of Opioids at the Injured Nerve Trunk Than at Its Peripheral Terminals in Neuropathic Pain
    Dominika Labuz and Halina Machelska
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 535-544; DOI: https://doi.org/10.1124/jpet.113.205344
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    Physical Presence of Nor-Binaltorphimine in Mouse Brain over 21 Days after a Single Administration Corresponds to Its Long-Lasting Antagonistic Effect on κ-Opioid Receptors
    Kshitij A. Patkar, Jinhua Wu, Michelle L. Ganno, Harminder D. Singh, Nicolette C. Ross, Khampaseuth Rasakham, Lawrence Toll and Jay P. McLaughlin
    Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 545-554; DOI: https://doi.org/10.1124/jpet.113.206086
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Journal of Pharmacology and Experimental Therapeutics: 346 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 346, Issue 3
1 Sep 2013
  • Table of Contents
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