Journal of Pharmacology and Experimental Therapeutics: 346 (3)

September 01, 2013; Volume 346,Issue 3

Highlighted Papers

You have access
Drug-Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073
Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HI
You have access
A Compound Selective for I₁-Imidazoline Receptors Improves Metabolic Syndrome
Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HIa
You have access
JNJ-26854165 Induces Cell Death through Inhibition of Cholesterol Transport
Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HIb
You have access
Pharmacokinetics and Pharmacodynamics of the GCP II Inhibitor 2-MPPA
Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 342; DOI: https://doi.org/10.1124/jpet.113.0913HIc

Perspectives in Pharmacology

You have access
Pharmacology at Work for Cardio-Oncology: Ranolazine to Treat Early Cardiotoxicity Induced by Antitumor Drugs
Giorgio Minotti

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 343-349; DOI: https://doi.org/10.1124/jpet.113.204057

Behavioral Pharmacology

You have access
Differential Drug–Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073: Implications for Drug Abuse Liability and Pain Therapy
Lisa K. Brents, Sarah M. Zimmerman, Amanda R. Saffell, Paul L. Prather and William E. Fantegrossi

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 350-361; DOI: https://doi.org/10.1124/jpet.113.206003

Cardiovascular

You have access
Fetal Rat Hearts Do Not Display Acute Cardiotoxicity in Response to Maternal Doxorubicin Treatment
Mina Mhallem Gziri, Peter Pokreisz, Rita De Vos, Eric Verbeken, Frédéric Debiève, Luc Mertens, Stefan P. Janssens and Frédéric Amant

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 362-369; DOI: https://doi.org/10.1124/jpet.113.205419
You have access
A New Pyrroline Compound Selective for I₁-Imidazoline Receptors Improves Metabolic Syndrome in Rats
Lyne Fellmann, Véronique Regnault, Hugues Greney, Vincent Gasparik, Adeline Muscat, Jean-Pierre Max, Luc Gigou, Valérie Oréa, Gérard Chetrite, Anne Pizard, Nathalie Niederhoffer, Claude Julien, Patrick Lacolley, Bruno Fève and Pascal Bousquet

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 370-380; DOI: https://doi.org/10.1124/jpet.113.205328

Chemotherapy, Antibiotics, and Gene Therapy

You have access
The Novel Anticancer Agent JNJ-26854165 Induces Cell Death through Inhibition of Cholesterol Transport and Degradation of ABCA1
Richard J. Jones, Dongmin Gu, Chad C. Bjorklund, Isere Kuiatse, Alan T. Remaley, Tarig Bashir, Veronique Vreys and Robert Z. Orlowski

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 381-392; DOI: https://doi.org/10.1124/jpet.113.204958
You have access
DNA-Damaging Imidazoacridinone C-1311 Induces Autophagy followed by Irreversible Growth Arrest and Senescence in Human Lung Cancer Cells
Joanna Polewska, Anna Skwarska, Ewa Augustin and Jerzy Konopa

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 393-405; DOI: https://doi.org/10.1124/jpet.113.203851

Drug Discovery and Translational Medicine

You have access
Pharmacokinetics and Pharmacodynamics of the Glutamate Carboxypeptidase II Inhibitor 2-MPPA Show Prolonged Alleviation of Neuropathic Pain through an Indirect Mechanism
James J. Vornov, Krystyna M. Wozniak, Ying Wu, Camilo Rojas, Rana Rais and Barbara S. Slusher

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 406-413; DOI: https://doi.org/10.1124/jpet.113.205039
You have access
Effect of the Mixed Phosphodiesterase 3/4 Inhibitor RPL554 on Human Isolated Bronchial Smooth Muscle Tone
Luigino Calzetta, Clive P. Page, Domenico Spina, Mario Cazzola, Paola Rogliani, Francesco Facciolo and Maria Gabriella Matera

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 414-423; DOI: https://doi.org/10.1124/jpet.113.204644
You have access
Anodal Iontophoresis of a Soluble Guanylate Cyclase Stimulator Induces a Sustained Increase in Skin Blood Flow in Rats
Sylvain Kotzki, Matthieu Roustit, Claire Arnaud, Jean Boutonnat, Sophie Blaise, Diane Godin-Ribuot and Jean-Luc Cracowski

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 424-431; DOI: https://doi.org/10.1124/jpet.113.205484
You have access
Modeling Tumor Response after Combined Administration of Different Immune-Stimulatory Agents
Zinnia P. Parra-Guillen, Pedro Berraondo, Benjamin Ribba and Iñaki F. Trocóniz

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 432-442; DOI: https://doi.org/10.1124/jpet.113.206961

Endocrine and Diabetes

You have access
Chronic Treatment with Novel GPR40 Agonists Improve Whole-Body Glucose Metabolism Based on the Glucose-Dependent Insulin Secretion
Hirotsugu Tanaka, Shigeru Yoshida, Hiroyuki Oshima, Hideaki Minoura, Kenji Negoro, Takao Yamazaki, Shuichi Sakuda, Fumiyoshi Iwasaki, Tetsuo Matsui and Masayuki Shibasaki

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 443-452; DOI: https://doi.org/10.1124/jpet.113.206466

Gastrointestinal, Hepatic, Pulmonary, and Renal

You have access
Short- and Long-Term Regulation of Intestinal Na⁺/H⁺ Exchange Activity Associated with TLR2 Receptor Activation Is Independent of Nuclear Factor-κB Signaling
José Miguel Cabral, Patrício Soares-da-Silva and Fernando Magro

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 453-464; DOI: https://doi.org/10.1124/jpet.113.204602
You have access
NLRP3 Inflammasome Knockout Mice Are Protected against Ischemic but Not Cisplatin-Induced Acute Kidney Injury
Hyun-Jung Kim, Dong Won Lee, Kameswaran Ravichandran, Daniel O. Keys, Ali Akcay, Quocan Nguyen, Zhibin He, Alkesh Jani, Danica Ljubanovic and Charles L. Edelstein

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 465-472; DOI: https://doi.org/10.1124/jpet.113.205732

Inflammation, Immunopharmacology, and Asthma

You have access
Concurrent Agonism of Adenosine A_2B and Glucocorticoid Receptors in Human Airway Epithelial Cells Cooperatively Induces Genes with Anti-Inflammatory Potential: A Novel Approach to Treat Chronic Obstructive Pulmonary Disease
Stephanie Greer, Cara W. Page, Taruna Joshi, Dong Yan, Robert Newton and Mark A. Giembycz

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 473-485; DOI: https://doi.org/10.1124/jpet.113.206284

Metabolism, Transport, and Pharmacogenomics

You have access
Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Gene Dosage on Plasma Pharmacokinetics and Brain Accumulation of Dasatinib, Sorafenib, and Sunitinib
Seng Chuan Tang, Niels de Vries, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 486-494; DOI: https://doi.org/10.1124/jpet.113.205583
You have access
Substrate-Dependent Inhibition of Human MATE1 by Cationic Ionic Liquids
Lucy J. Martínez-Guerrero and Stephen H. Wright

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 495-503; DOI: https://doi.org/10.1124/jpet.113.204206
You have access
Toxicokinetics/Toxicodynamics of γ-Hydroxybutyrate-Ethanol Intoxication: Evaluation of Potential Treatment Strategies
Bridget L. Morse and Marilyn E. Morris

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 504-513; DOI: https://doi.org/10.1124/jpet.113.206250

Neuropharmacology

You have access
Pharmacological Characterization of JNJ-40068782, a New Potent, Selective, and Systemically Active Positive Allosteric Modulator of the mGlu2 Receptor and Its Radioligand [³H]JNJ-40068782
Hilde Lavreysen, Xavier Langlois, Abdel Ahnaou, Wilhelmus Drinkenburg, Paula te Riele, Ilse Biesmans, Ilse Van der Linden, Luc Peeters, Anton Megens, Cindy Wintmolders, Jose Maria Cid, Andrés A. Trabanco, Jose Ignacio Andrés, Frank M. Dautzenberg, Robert Lütjens, Gregor Macdonald and John R. Atack

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 514-527; DOI: https://doi.org/10.1124/jpet.113.204990
You have access
Long-Lasting Attenuation of Amygdala-Kindled Seizures after Convection-Enhanced Delivery of Botulinum Neurotoxins A and B into the Amygdala in Rats
Maciej Gasior, Rebecca Tang and Michael A. Rogawski

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 528-534; DOI: https://doi.org/10.1124/jpet.113.205070
You have access
Stronger Antinociceptive Efficacy of Opioids at the Injured Nerve Trunk Than at Its Peripheral Terminals in Neuropathic Pain
Dominika Labuz and Halina Machelska

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 535-544; DOI: https://doi.org/10.1124/jpet.113.205344
You have access
Physical Presence of Nor-Binaltorphimine in Mouse Brain over 21 Days after a Single Administration Corresponds to Its Long-Lasting Antagonistic Effect on κ-Opioid Receptors
Kshitij A. Patkar, Jinhua Wu, Michelle L. Ganno, Harminder D. Singh, Nicolette C. Ross, Khampaseuth Rasakham, Lawrence Toll and Jay P. McLaughlin

Journal of Pharmacology and Experimental Therapeutics September 2013, 346 (3) 545-554; DOI: https://doi.org/10.1124/jpet.113.206086

Main menu

User menu

Search

Table of Contents

Highlighted Papers

Perspectives in Pharmacology

Behavioral Pharmacology

Cardiovascular

Chemotherapy, Antibiotics, and Gene Therapy

Drug Discovery and Translational Medicine

Endocrine and Diabetes

Gastrointestinal, Hepatic, Pulmonary, and Renal

Inflammation, Immunopharmacology, and Asthma

Metabolism, Transport, and Pharmacogenomics

Neuropharmacology

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals