Pharmacology of AMG 416 (Velcalcetide), a Novel Peptide Agonist of the Calcium-Sensing Receptor, for the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients

Sarah Walter; Amos Baruch; Jin Dong; James E. Tomlinson; Shawn T. Alexander; Julie Janes; Tom Hunter; Qun Yin; Derek Maclean; Gregory Bell; Dirk B. Mendel; Randolph M. Johnson; Felix Karim

doi:10.1124/jpet.113.204834

Research ArticleDrug Discovery and Translational Medicine

Pharmacology of AMG 416 (Velcalcetide), a Novel Peptide Agonist of the Calcium-Sensing Receptor, for the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients

Sarah Walter, Amos Baruch, Jin Dong, James E. Tomlinson, Shawn T. Alexander, Julie Janes, Tom Hunter, Qun Yin, Derek Maclean, Gregory Bell, Dirk B. Mendel, Randolph M. Johnson and Felix Karim

Journal of Pharmacology and Experimental Therapeutics August 2013, 346 (2) 229-240; DOI: https://doi.org/10.1124/jpet.113.204834

Sarah Walter

Amgen, Inc., South San Francisco, California (S.W., A.B., J.D., J.E.T., S.T.A., J.J., T.H., Q.Y., D.B.M., G.B., D.M., R.M.J., F.K.); and Department of Medicine, University of California, San Francisco, California (G.B.)

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Amos Baruch

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Jin Dong

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James E. Tomlinson

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Shawn T. Alexander

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Julie Janes

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Tom Hunter

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Qun Yin

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Derek Maclean

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Gregory Bell

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Dirk B. Mendel

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Randolph M. Johnson

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Felix Karim

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Journal of Pharmacology and Experimental Therapeutics

Vol. 346, Issue 2

1 Aug 2013

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Research ArticleDrug Discovery and Translational Medicine

AMG 416 (Velcalcetide) Activates the Calcium Sensing Receptor

Sarah Walter, Amos Baruch, Jin Dong, James E. Tomlinson, Shawn T. Alexander, Julie Janes, Tom Hunter, Qun Yin, Derek Maclean, Gregory Bell, Dirk B. Mendel, Randolph M. Johnson and Felix Karim

Journal of Pharmacology and Experimental Therapeutics August 1, 2013, 346 (2) 229-240; DOI: https://doi.org/10.1124/jpet.113.204834

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Research ArticleDrug Discovery and Translational Medicine

AMG 416 (Velcalcetide) Activates the Calcium Sensing Receptor

Sarah Walter, Amos Baruch, Jin Dong, James E. Tomlinson, Shawn T. Alexander, Julie Janes, Tom Hunter, Qun Yin, Derek Maclean, Gregory Bell, Dirk B. Mendel, Randolph M. Johnson and Felix Karim

Journal of Pharmacology and Experimental Therapeutics August 1, 2013, 346 (2) 229-240; DOI: https://doi.org/10.1124/jpet.113.204834

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