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Research ArticleDrug Discovery and Translational Medicine

Inhibition of Btk with CC-292 Provides Early Pharmacodynamic Assessment of Activity in Mice and Humans

Erica K. Evans, Richland Tester, Sharon Aslanian, Russell Karp, Michael Sheets, Matthew T. Labenski, Steven R. Witowski, Heather Lounsbury, Prasoon Chaturvedi, Hormoz Mazdiyasni, Zhendong Zhu, Mariana Nacht, Martin I. Freed, Russell C. Petter, Alex Dubrovskiy, Juswinder Singh and William F. Westlin
Journal of Pharmacology and Experimental Therapeutics August 2013, 346 (2) 219-228; DOI: https://doi.org/10.1124/jpet.113.203489
Erica K. Evans
Celgene Avilomics Research, Bedford, Massachusetts
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Richland Tester
Celgene Avilomics Research, Bedford, Massachusetts
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Sharon Aslanian
Celgene Avilomics Research, Bedford, Massachusetts
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Russell Karp
Celgene Avilomics Research, Bedford, Massachusetts
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Michael Sheets
Celgene Avilomics Research, Bedford, Massachusetts
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Matthew T. Labenski
Celgene Avilomics Research, Bedford, Massachusetts
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Steven R. Witowski
Celgene Avilomics Research, Bedford, Massachusetts
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Heather Lounsbury
Celgene Avilomics Research, Bedford, Massachusetts
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Prasoon Chaturvedi
Celgene Avilomics Research, Bedford, Massachusetts
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Hormoz Mazdiyasni
Celgene Avilomics Research, Bedford, Massachusetts
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Zhendong Zhu
Celgene Avilomics Research, Bedford, Massachusetts
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Mariana Nacht
Celgene Avilomics Research, Bedford, Massachusetts
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Martin I. Freed
Celgene Avilomics Research, Bedford, Massachusetts
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Russell C. Petter
Celgene Avilomics Research, Bedford, Massachusetts
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Alex Dubrovskiy
Celgene Avilomics Research, Bedford, Massachusetts
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Juswinder Singh
Celgene Avilomics Research, Bedford, Massachusetts
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William F. Westlin
Celgene Avilomics Research, Bedford, Massachusetts
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Journal of Pharmacology and Experimental Therapeutics: 346 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 346, Issue 2
1 Aug 2013
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Research ArticleDrug Discovery and Translational Medicine

Btk Inhibition with the Covalent Inhibitor CC-292

Erica K. Evans, Richland Tester, Sharon Aslanian, Russell Karp, Michael Sheets, Matthew T. Labenski, Steven R. Witowski, Heather Lounsbury, Prasoon Chaturvedi, Hormoz Mazdiyasni, Zhendong Zhu, Mariana Nacht, Martin I. Freed, Russell C. Petter, Alex Dubrovskiy, Juswinder Singh and William F. Westlin
Journal of Pharmacology and Experimental Therapeutics August 1, 2013, 346 (2) 219-228; DOI: https://doi.org/10.1124/jpet.113.203489

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Research ArticleDrug Discovery and Translational Medicine

Btk Inhibition with the Covalent Inhibitor CC-292

Erica K. Evans, Richland Tester, Sharon Aslanian, Russell Karp, Michael Sheets, Matthew T. Labenski, Steven R. Witowski, Heather Lounsbury, Prasoon Chaturvedi, Hormoz Mazdiyasni, Zhendong Zhu, Mariana Nacht, Martin I. Freed, Russell C. Petter, Alex Dubrovskiy, Juswinder Singh and William F. Westlin
Journal of Pharmacology and Experimental Therapeutics August 1, 2013, 346 (2) 219-228; DOI: https://doi.org/10.1124/jpet.113.203489
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