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Research ArticleInflammation, Immunopharmacology, and Asthma

A Novel Macrolide Solithromycin Exerts Superior Anti-inflammatory Effect via NF-κB Inhibition

Yoshiki Kobayashi, Hiroo Wada, Christos Rossios, Dai Takagi, Manabu Higaki, Shin'ichiro Mikura, Hajime Goto, Peter J. Barnes and Kazuhiro Ito
Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 76-84; DOI: https://doi.org/10.1124/jpet.112.200733
Yoshiki Kobayashi
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Hiroo Wada
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Christos Rossios
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Dai Takagi
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Manabu Higaki
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Shin'ichiro Mikura
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Hajime Goto
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Peter J. Barnes
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Kazuhiro Ito
Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom (Y.K., C.R., D.T., P.J.B., K.I.); and Department of Respiratory Medicine, Kyorin University, School of Medicine, Tokyo, Japan (H.W., M.H., S.M., H.G.)
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Journal of Pharmacology and Experimental Therapeutics: 345 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 345, Issue 1
1 Apr 2013
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Research ArticleInflammation, Immunopharmacology, and Asthma

Anti-inflammatory Effect of Solithromycin

Yoshiki Kobayashi, Hiroo Wada, Christos Rossios, Dai Takagi, Manabu Higaki, Shin'ichiro Mikura, Hajime Goto, Peter J. Barnes and Kazuhiro Ito
Journal of Pharmacology and Experimental Therapeutics April 1, 2013, 345 (1) 76-84; DOI: https://doi.org/10.1124/jpet.112.200733

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Research ArticleInflammation, Immunopharmacology, and Asthma

Anti-inflammatory Effect of Solithromycin

Yoshiki Kobayashi, Hiroo Wada, Christos Rossios, Dai Takagi, Manabu Higaki, Shin'ichiro Mikura, Hajime Goto, Peter J. Barnes and Kazuhiro Ito
Journal of Pharmacology and Experimental Therapeutics April 1, 2013, 345 (1) 76-84; DOI: https://doi.org/10.1124/jpet.112.200733
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