Research ArticleDrug Discovery and Translational Medicine
In Vitro–In Vivo Correlation of the Inhibition Potency of Sodium-Glucose Cotransporter Inhibitors in Rat: A Pharmacokinetic and Pharmacodynamic Modeling Approach
Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Hitoshi Hagita, Maiko Takada, Miho Ayabe, Yoshinori Aso, Masaki Ishigai and Sachiya Ikeda
Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 52-61; DOI: https://doi.org/10.1124/jpet.113.203125
Koji Yamaguchi
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Motohiro Kato
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Masayuki Suzuki
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Hitoshi Hagita
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Maiko Takada
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Miho Ayabe
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Yoshinori Aso
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Masaki Ishigai
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
Sachiya Ikeda
Research Division, Chugai Pharmaceutical Co., Ltd., (K.Y., M.K., M.S., M.T., M.A., Y.A., M.I., S.I.), and Chugai Research Institute for Medical Science, Inc. (H.H.), Gotemba, Shizuoka, Japan
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Research ArticleDrug Discovery and Translational Medicine
IVIVC for Inhibition Potency of SGLT Inhibitors
Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Hitoshi Hagita, Maiko Takada, Miho Ayabe, Yoshinori Aso, Masaki Ishigai and Sachiya Ikeda
Journal of Pharmacology and Experimental Therapeutics April 1, 2013, 345 (1) 52-61; DOI: https://doi.org/10.1124/jpet.113.203125
Research ArticleDrug Discovery and Translational Medicine
IVIVC for Inhibition Potency of SGLT Inhibitors
Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Hitoshi Hagita, Maiko Takada, Miho Ayabe, Yoshinori Aso, Masaki Ishigai and Sachiya Ikeda
Journal of Pharmacology and Experimental Therapeutics April 1, 2013, 345 (1) 52-61; DOI: https://doi.org/10.1124/jpet.113.203125
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