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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

April 01, 2013; Volume 345,Issue 1

Highlighted Papers

  • You have access
    Paclitaxel Ameliorates Lipopolysaccharide-Induced Kidney Injury by Binding Myeloid Differentiation Protein-2
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 1; DOI: https://doi.org/10.1124/jpet.112.0413HI
  • You have access
    Quantifying the Attenuation of the Ketamine Pharmacological Magnetic Resonance Imaging Response in Humans
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 1; DOI: https://doi.org/10.1124/jpet.112.0413HIa
  • You have access
    A Novel Macrolide Solithromycin Exerts Superior Anti-inflammatory Effect
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 1; DOI: https://doi.org/10.1124/jpet.112.0413HIb
  • You have access
    Refining the UGT1A Haplotype Associated with Irinotecan-Induced Hematological Toxicity in Patients with Colorectal Cancer
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 1; DOI: https://doi.org/10.1124/jpet.112.0413HIc

Perspectives in Pharmacology

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    Mending Leaky Blood Vessels: The Angiopoietin-Tie2 Pathway in Sepsis
    Sascha David, Philipp Kümpers, Paul van Slyke and Samir M. Parikh
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 2-6; DOI: https://doi.org/10.1124/jpet.112.201061

Cardiovascular

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    Peroxynitrite Mediates Testosterone-Induced Vasodilation of Microvascular Resistance Vessels
    Yashoda Puttabyatappa, John N. Stallone, Adviye Ergul, Azza B. El-Remessy, Sanjiv Kumar, Stephen Black, Maribeth Johnson, Mary P. Owen and Richard E. White
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 7-14; DOI: https://doi.org/10.1124/jpet.112.201947
  • You have access
    Pharmacologic Protein Kinase Cα Inhibition Uncouples Human Platelet-Stimulated Angiogenesis from Collagen-Induced Aggregation
    Cesar Moncada de la Rosa, Aneta Radziwon-Balicka, Haitham El-Sikhry, John Seubert, Peter P. Ruvolo, Marek W. Radomski and Paul Jurasz
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 15-24; DOI: https://doi.org/10.1124/jpet.112.200881
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    Prolyl-Hydroxylase Inhibition Preserves Endothelial Cell Function in a Rat Model of Vascular Ischemia Reperfusion Injury
    Enikő Barnucz, Gábor Veres, Péter Hegedűs, Stephanie Klein, Raphael Zöller, Tamás Radovits, Sevil Korkmaz, Ferenc Horkay, Béla Merkely, Matthias Karck and Gábor Szabó
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 25-31; DOI: https://doi.org/10.1124/jpet.112.200790
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    Impaired Function of Prejunctional Adenosine A1 Receptors Expressed by Perivascular Sympathetic Nerves in DOCA-Salt Hypertensive Rats
    Sutheera Sangsiri, Hua Dong, Gregory M. Swain, James J. Galligan and Hui Xu
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 32-40; DOI: https://doi.org/10.1124/jpet.112.199612

Drug Discovery and Translational Medicine

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    Parallel Buprenorphine phMRI Responses in Conscious Rodents and Healthy Human Subjects
    Lino Becerra, Jaymin Upadhyay, Pei-Ching Chang, James Bishop, Julie Anderson, Richard Baumgartner, Adam J. Schwarz, Alexandre Coimbra, Diana Wallin, Lauren Nutile, Edward George, Gary Maier, Soujanya Sunkaraneni, Smriti Iyengar, Jeffrey L. Evelhoch, David Bleakman, Richard Hargreaves and David Borsook
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 41-51; DOI: https://doi.org/10.1124/jpet.112.201145
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    In Vitro–In Vivo Correlation of the Inhibition Potency of Sodium-Glucose Cotransporter Inhibitors in Rat: A Pharmacokinetic and Pharmacodynamic Modeling Approach
    Koji Yamaguchi, Motohiro Kato, Masayuki Suzuki, Hitoshi Hagita, Maiko Takada, Miho Ayabe, Yoshinori Aso, Masaki Ishigai and Sachiya Ikeda
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 52-61; DOI: https://doi.org/10.1124/jpet.113.203125

Endocrine and Diabetes

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    Adiponectin Enhances Calcium Dependency of Mouse Bladder Contraction Mediated by Protein Kinase Cα Expression
    Koji Nobe, Akiko Fujii, Kiyomi Saito, Takaharu Negoro, Yoshio Ogawa, Yasuko Nakano, Terumasa Hashimoto and Kazuo Honda
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 62-68; DOI: https://doi.org/10.1124/jpet.112.202028

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Paclitaxel Ameliorates Lipopolysaccharide-Induced Kidney Injury by Binding Myeloid Differentiation Protein-2 to Block Toll-Like Receptor 4–Mediated Nuclear Factor-κB Activation and Cytokine Production
    Dongshan Zhang, Yijian Li, Yu Liu, Xudong Xiang and Zheng Dong
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 69-75; DOI: https://doi.org/10.1124/jpet.112.202481

Inflammation, Immunopharmacology, and Asthma

  • You have access
    A Novel Macrolide Solithromycin Exerts Superior Anti-inflammatory Effect via NF-κB Inhibition
    Yoshiki Kobayashi, Hiroo Wada, Christos Rossios, Dai Takagi, Manabu Higaki, Shin'ichiro Mikura, Hajime Goto, Peter J. Barnes and Kazuhiro Ito
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 76-84; DOI: https://doi.org/10.1124/jpet.112.200733
  • You have access
    Positional Isomers of Aspirin Are Equally Potent in Inhibiting Colon Cancer Cell Growth: Differences in Mode of Cyclooxygenase Inhibition
    Ravinder Kodela, Mitali Chattopadhyay, Satindra Goswami, Zong Yuan Gan, Praveen P. N. Rao, Kamran V. Nia, Carlos A. Velázquez-Martínez and Khosrow Kashfi
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 85-94; DOI: https://doi.org/10.1124/jpet.112.201970

Metabolism, Transport, and Pharmacogenomics

  • You have access
    Refining the UGT1A Haplotype Associated with Irinotecan-Induced Hematological Toxicity in Metastatic Colorectal Cancer Patients Treated with 5-Fluorouracil/Irinotecan-Based Regimens
    Éric Lévesque, Anne-Sophie Bélanger, Mario Harvey, Félix Couture, Derek Jonker, Federico Innocenti, Erica Cecchin, Giuseppe Toffoli and Chantal Guillemette
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 95-101; DOI: https://doi.org/10.1124/jpet.112.202242
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    Effects of Monocarboxylate Transporter Inhibition on the Oral Toxicokinetics/Toxicodynamics of γ-Hydroxybutyrate and γ-Butyrolactone
    Bridget L. Morse and Marilyn E. Morris
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 102-110; DOI: https://doi.org/10.1124/jpet.112.202796
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    Saturable Active Efflux by P-Glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier Leads to Nonlinear Distribution of Elacridar to the Central Nervous System
    Ramola Sane, Sagar Agarwal, Rajendar K. Mittapalli and William F. Elmquist
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 111-124; DOI: https://doi.org/10.1124/jpet.112.199786

Neuropharmacology

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    Neuroprotective Efficacy and Pharmacokinetic Behavior of Novel Anti-Inflammatory Para-Phenyl Substituted Diindolylmethanes in a Mouse Model of Parkinson’s Disease
    Briana R. De Miranda, James A. Miller, Ryan J. Hansen, Paul J. Lunghofer, Stephen Safe, Daniel L. Gustafson, Dorothy Colagiovanni and Ronald B. Tjalkens
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 125-138; DOI: https://doi.org/10.1124/jpet.112.201558
  • You have access
    Group I mGluRs Evoke K-ATP Current by Intracellular Ca2+ Mobilization in Rat Subthalamus Neurons
    Ke-Zhong Shen and Steven W. Johnson
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 139-150; DOI: https://doi.org/10.1124/jpet.112.201566
  • You have access
    Quantifying the Attenuation of the Ketamine Pharmacological Magnetic Resonance Imaging Response in Humans: A Validation Using Antipsychotic and Glutamatergic Agents
    O. M. Doyle, S. De Simoni, A. J. Schwarz, C. Brittain, O. G. O’Daly, S. C. R. Williams and M. A. Mehta
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 151-160; DOI: https://doi.org/10.1124/jpet.112.201665
  • You have access
    Upregulation of Nuclear Factor of Activated T-Cells by Nerve Injury Contributes to Development of Neuropathic Pain
    You-Qing Cai, Shao-Rui Chen and Hui-Lin Pan
    Journal of Pharmacology and Experimental Therapeutics April 2013, 345 (1) 161-168; DOI: https://doi.org/10.1124/jpet.112.202192
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 345 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 345, Issue 1
1 Apr 2013
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
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  • Highlighted Papers
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  • Drug Discovery and Translational Medicine
  • Endocrine and Diabetes
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Inflammation, Immunopharmacology, and Asthma
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
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  • Potential Clinical Uses of CBG
  • Ocular Drug Delivery: Past, Present, and Future
  • Rho GTPase–Pathway Inhibitor Reduces Markers of Fibrosis
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