Research ArticleNeuropharmacology
A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine
Scott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. Violin
Journal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Scott M. DeWire
Trevena Inc, King of Prussia, Pennsylvania
Dennis S. Yamashita
Trevena Inc, King of Prussia, Pennsylvania
David H. Rominger
Trevena Inc, King of Prussia, Pennsylvania
Guodong Liu
Trevena Inc, King of Prussia, Pennsylvania
Conrad L. Cowan
Trevena Inc, King of Prussia, Pennsylvania
Thomas M. Graczyk
Trevena Inc, King of Prussia, Pennsylvania
Xiao-Tao Chen
Trevena Inc, King of Prussia, Pennsylvania
Philip M. Pitis
Trevena Inc, King of Prussia, Pennsylvania
Dimitar Gotchev
Trevena Inc, King of Prussia, Pennsylvania
Catherine Yuan
Trevena Inc, King of Prussia, Pennsylvania
Michael Koblish
Trevena Inc, King of Prussia, Pennsylvania
Michael W. Lark
Trevena Inc, King of Prussia, Pennsylvania
Jonathan D. Violin
Trevena Inc, King of Prussia, Pennsylvania

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Research ArticleNeuropharmacology
TRV130: A μ-Opioid Receptor-Biased Ligand
Scott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. Violin
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Research ArticleNeuropharmacology
TRV130: A μ-Opioid Receptor-Biased Ligand
Scott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. Violin
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
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