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Research ArticleNeuropharmacology

A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine

Scott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. Violin
Journal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
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Research ArticleNeuropharmacology

TRV130: A μ-Opioid Receptor-Biased Ligand

Scott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. Violin
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
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