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Research ArticleDrug Discovery and Translational Medicine

5-Benzylglycinyl-Amiloride Kills Proliferating and Nonproliferating Malignant Glioma Cells through Caspase-Independent Necroptosis Mediated by Apoptosis-Inducing Factor

Nagarekha Pasupuleti, Leonardo Leon, Kermit L. Carraway III and Fredric Gorin
Journal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 600-615; DOI: https://doi.org/10.1124/jpet.112.200519

Article Information

vol. 344 no. 3 600-615
DOI 
https://doi.org/10.1124/jpet.112.200519
PubMed 
23241369
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 24, 2012
  • Accepted December 13, 2012
  • Published online February 19, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nagarekha Pasupuleti,
  2. Leonardo Leon,
  3. Kermit L. Carraway III, and
  4. Fredric Gorin
  1. Department of Neurology, School of Medicine and Department of Molecular Biosciences, School of Veterinary Medicine (N.P., F.G.) and Department of Biochemistry and Molecular Medicine and Comprehensive Cancer Center (L.L., K.L.C.), University of California, Davis, California
  1. Address correspondence to:
    Fredric A. Gorin, Department of Neurology (Med), Department of Molecular Biosciences (Vet), University of California, Davis Comprehensive Cancer Center. E-mail: fagorin{at}ucdavis.edu
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Research ArticleDrug Discovery and Translational Medicine

Amiloride Analog Kills Gliomas by Necroptosis

Nagarekha Pasupuleti, Leonardo Leon, Kermit L. Carraway and Fredric Gorin
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 600-615; DOI: https://doi.org/10.1124/jpet.112.200519
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