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Research ArticleDrug Discovery and Translational Medicine

Structure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1

Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. Mayo
Journal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646

Article Information

vol. 344 no. 3 589-599
DOI 
https://doi.org/10.1124/jpet.112.199646
PubMed 
23232447
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 27, 2012
  • Accepted December 10, 2012
  • Published online February 19, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ruud P. M. Dings,
  2. Nigam Kumar,
  3. Michelle C. Miller,
  4. Melissa Loren,
  5. Huzaifa Rangwala,
  6. Thomas R. Hoye, and
  7. Kevin H. Mayo
  1. Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
  1. Address correspondence to:
    Kevin H. Mayo, Department of Biochemistry, 6-155 Jackson Hall, University of Minnesota, 321 Church Street, Minneapolis, MN 55455. E-mail: mayox001{at}umn.edu
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Research ArticleDrug Discovery and Translational Medicine

Optimizing DBF-Anginex Mimetics

Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. Mayo
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
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