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Research ArticleDrug Discovery and Translational Medicine

Structure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1

Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. Mayo
Journal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
Ruud P. M. Dings
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Nigam Kumar
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Michelle C. Miller
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Melissa Loren
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Huzaifa Rangwala
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Thomas R. Hoye
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Kevin H. Mayo
Departments of Biochemistry, Molecular Biology & Biophysics (R.P.M.D., N.K., M.C.M., M.L., K.H.M.), and Chemistry (H.R., T.R.H.), University of Minnesota, Minneapolis, Minnesota
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Journal of Pharmacology and Experimental Therapeutics: 344 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 344, Issue 3
1 Mar 2013
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Research ArticleDrug Discovery and Translational Medicine

Optimizing DBF-Anginex Mimetics

Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. Mayo
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646

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Research ArticleDrug Discovery and Translational Medicine

Optimizing DBF-Anginex Mimetics

Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. Mayo
Journal of Pharmacology and Experimental Therapeutics March 1, 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
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