Index by author
March 01, 2013; Volume 344,Issue 3
A
Albright, Charles F.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Angiolillo, Dominick J.
- You have accessCarboxylesterase 1 as a Determinant of Clopidogrel Metabolism and ActivationHao-Jie Zhu, Xinwen Wang, Brian E. Gawronski, Bryan J. Brinda, Dominick J. Angiolillo and John S. MarkowitzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 665-672; DOI: https://doi.org/10.1124/jpet.112.201640
B
Balimane, Praveen
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Banks, William A.
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Barten, Donna M.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Bergman, Jack
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Berman, Robert M.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Bournique, Bruno
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Brinda, Bryan J.
- You have accessCarboxylesterase 1 as a Determinant of Clopidogrel Metabolism and ActivationHao-Jie Zhu, Xinwen Wang, Brian E. Gawronski, Bryan J. Brinda, Dominick J. Angiolillo and John S. MarkowitzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 665-672; DOI: https://doi.org/10.1124/jpet.112.201640
Bristol, Molly L.
- You have accessAutophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?Molly L. Bristol, Sean M. Emery, Paola Maycotte, Andrew Thorburn, Shweta Chakradeo and David A. GewirtzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 544-552; DOI: https://doi.org/10.1124/jpet.112.199802
Bronson, Joanne
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Burnham, Liam J.
- You have accessThe Antinociceptive Effect of Milnacipran in the Monosodium Iodoacetate Model of Osteoarthritis Pain and Its Relation to Changes in Descending InhibitionLiam J. Burnham and Anthony H. DickensonJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 696-707; DOI: https://doi.org/10.1124/jpet.112.199489
Burton, Catherine
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
C
Campo, Brice
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Carraway, Kermit L.
- You have access5-Benzylglycinyl-Amiloride Kills Proliferating and Nonproliferating Malignant Glioma Cells through Caspase-Independent Necroptosis Mediated by Apoptosis-Inducing FactorNagarekha Pasupuleti, Leonardo Leon, Kermit L. Carraway and Fredric GorinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 600-615; DOI: https://doi.org/10.1124/jpet.112.200519
Castaneda, Lorna
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Chakradeo, Shweta
- You have accessAutophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?Molly L. Bristol, Sean M. Emery, Paola Maycotte, Andrew Thorburn, Shweta Chakradeo and David A. GewirtzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 544-552; DOI: https://doi.org/10.1124/jpet.112.199802
Charvin, Delphine
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Chen, Cliff
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Chen, Liang
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Chen, Xiao-Tao
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Cheng, Kejun
- You have accessDiscriminative Stimulus Effects of the GABAB Receptor-Positive Modulator rac-BHFF: Comparison with GABAB Receptor Agonists and Drugs of AbuseWouter Koek, Kejun Cheng and Kenner C. RiceJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 553-560; DOI: https://doi.org/10.1124/jpet.112.202226
Coric, Vlad
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Cowan, Conrad L.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Croy, Johnny E.
- You have accessAn Engineered Human Follistatin Variant: Insights into the Pharmacokinetic and Pharmocodynamic Relationships of a Novel Molecule with Broad Therapeutic PotentialAmita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, Bryan E. Jones and Johnny E. CroyJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 616-623; DOI: https://doi.org/10.1124/jpet.112.201491
Cui, Tuan
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
D
Datta-Mannan, Amita
- You have accessAn Engineered Human Follistatin Variant: Insights into the Pharmacokinetic and Pharmocodynamic Relationships of a Novel Molecule with Broad Therapeutic PotentialAmita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, Bryan E. Jones and Johnny E. CroyJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 616-623; DOI: https://doi.org/10.1124/jpet.112.201491
Delatte, Marcus S.
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Denton, R. Rex
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
DeWire, Scott M.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Dickenson, Anthony H.
- You have accessThe Antinociceptive Effect of Milnacipran in the Monosodium Iodoacetate Model of Osteoarthritis Pain and Its Relation to Changes in Descending InhibitionLiam J. Burnham and Anthony H. DickensonJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 696-707; DOI: https://doi.org/10.1124/jpet.112.199489
Dings, Ruud P. M.
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
Dockens, Randy C.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Dudek, Arkadiusz Z.
- You have accessMechanisms Limiting Distribution of the Threonine-Protein Kinase B-RaFV600E Inhibitor Dabrafenib to the Brain: Implications for the Treatment of Melanoma Brain MetastasesRajendar K. Mittapalli, Shruthi Vaidhyanathan, Arkadiusz Z. Dudek and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 655-664; DOI: https://doi.org/10.1124/jpet.112.201475
E
Elferink, Cornelis J.
- You have accessIdentification of Stanniocalcin 2 as a Novel Aryl Hydrocarbon Receptor Target GeneTod A. Harper, Aditya D. Joshi and Cornelis J. ElferinkJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 579-588; DOI: https://doi.org/10.1124/jpet.112.201111
Elmquist, William F.
- You have accessMechanisms Limiting Distribution of the Threonine-Protein Kinase B-RaFV600E Inhibitor Dabrafenib to the Brain: Implications for the Treatment of Melanoma Brain MetastasesRajendar K. Mittapalli, Shruthi Vaidhyanathan, Arkadiusz Z. Dudek and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 655-664; DOI: https://doi.org/10.1124/jpet.112.201475
Emery, Sean M.
- You have accessAutophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?Molly L. Bristol, Sean M. Emery, Paola Maycotte, Andrew Thorburn, Shweta Chakradeo and David A. GewirtzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 544-552; DOI: https://doi.org/10.1124/jpet.112.199802
Ercal, Nuran
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
F
Feldman, Howard
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Feng, Qin
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Finn, Terry
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
G
Gawronski, Brian E.
- You have accessCarboxylesterase 1 as a Determinant of Clopidogrel Metabolism and ActivationHao-Jie Zhu, Xinwen Wang, Brian E. Gawronski, Bryan J. Brinda, Dominick J. Angiolillo and John S. MarkowitzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 665-672; DOI: https://doi.org/10.1124/jpet.112.201640
Gewirtz, David A.
- You have accessAutophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?Molly L. Bristol, Sean M. Emery, Paola Maycotte, Andrew Thorburn, Shweta Chakradeo and David A. GewirtzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 544-552; DOI: https://doi.org/10.1124/jpet.112.199802
Gillman, Kevin W.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Girard, Francoise
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Gorin, Fredric
- You have access5-Benzylglycinyl-Amiloride Kills Proliferating and Nonproliferating Malignant Glioma Cells through Caspase-Independent Necroptosis Mediated by Apoptosis-Inducing FactorNagarekha Pasupuleti, Leonardo Leon, Kermit L. Carraway and Fredric GorinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 600-615; DOI: https://doi.org/10.1124/jpet.112.200519
Gotchev, Dimitar
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Graczyk, Thomas M.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Guss, Valerie
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
H
Han, Yong-Hae
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Harper, Tod A.
- You have accessIdentification of Stanniocalcin 2 as a Novel Aryl Hydrocarbon Receptor Target GeneTod A. Harper, Aditya D. Joshi and Cornelis J. ElferinkJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 579-588; DOI: https://doi.org/10.1124/jpet.112.201111
Harries, Nicholas
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Houston, John
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Hoye, Thomas R.
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
Hu, Yi-Yang
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Huang, Fu
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Huang, Shu-Pang
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
J
Jemal, Mohammed
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Jerman, Jeff
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Jones, Bryan E.
- You have accessAn Engineered Human Follistatin Variant: Insights into the Pharmacokinetic and Pharmocodynamic Relationships of a Novel Molecule with Broad Therapeutic PotentialAmita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, Bryan E. Jones and Johnny E. CroyJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 616-623; DOI: https://doi.org/10.1124/jpet.112.201491
Joshi, Aditya D.
- You have accessIdentification of Stanniocalcin 2 as a Novel Aryl Hydrocarbon Receptor Target GeneTod A. Harper, Aditya D. Joshi and Cornelis J. ElferinkJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 579-588; DOI: https://doi.org/10.1124/jpet.112.201111
K
Kalinichev, Mikhail
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Kallipatti, Sanjith
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Kangas, Brian D.
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Koblish, Michael
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Koek, Wouter
- You have accessDiscriminative Stimulus Effects of the GABAB Receptor-Positive Modulator rac-BHFF: Comparison with GABAB Receptor Agonists and Drugs of AbuseWouter Koek, Kejun Cheng and Kenner C. RiceJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 553-560; DOI: https://doi.org/10.1124/jpet.112.202226
Kovac, Andrej
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Krishnamurthy, Prasad
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Krishnan, Venkatesh
- You have accessAn Engineered Human Follistatin Variant: Insights into the Pharmacokinetic and Pharmocodynamic Relationships of a Novel Molecule with Broad Therapeutic PotentialAmita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, Bryan E. Jones and Johnny E. CroyJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 616-623; DOI: https://doi.org/10.1124/jpet.112.201491
Kumar, Nigam
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
L
Lark, Michael W.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Lentz, Kimberley A.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Leon, Leonardo
- You have access5-Benzylglycinyl-Amiloride Kills Proliferating and Nonproliferating Malignant Glioma Cells through Caspase-Independent Necroptosis Mediated by Apoptosis-Inducing FactorNagarekha Pasupuleti, Leonardo Leon, Kermit L. Carraway and Fredric GorinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 600-615; DOI: https://doi.org/10.1124/jpet.112.200519
Le Poul, Emmanuel
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Liu, Guodong
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Loren, Melissa
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
Lütjens, Robert
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
M
MacKenzie, Amanda E.
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Macor, John E.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Makriyannis, Alexandros
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Marathe, Punit
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Markowitz, John S.
- You have accessCarboxylesterase 1 as a Determinant of Clopidogrel Metabolism and ActivationHao-Jie Zhu, Xinwen Wang, Brian E. Gawronski, Bryan J. Brinda, Dominick J. Angiolillo and John S. MarkowitzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 665-672; DOI: https://doi.org/10.1124/jpet.112.201640
Maycotte, Paola
- You have accessAutophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?Molly L. Bristol, Sean M. Emery, Paola Maycotte, Andrew Thorburn, Shweta Chakradeo and David A. GewirtzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 544-552; DOI: https://doi.org/10.1124/jpet.112.199802
Mayo, Kevin H.
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
McIver, Edward G.
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Meredith, Jere E.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Miller, Michelle C.
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
Milligan, Graeme
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Mintier, Gabe
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Mittapalli, Rajendar K.
- You have accessMechanisms Limiting Distribution of the Threonine-Protein Kinase B-RaFV600E Inhibitor Dabrafenib to the Brain: Implications for the Treatment of Melanoma Brain MetastasesRajendar K. Mittapalli, Shruthi Vaidhyanathan, Arkadiusz Z. Dudek and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 655-664; DOI: https://doi.org/10.1124/jpet.112.201475
Morofuji, Yoichi
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Mutel, Vincent
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
N
Neale, Stuart A.
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Neetoo-Isseljee, Zaynab
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Nikas, Spyridon P.
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
O
Olson, Richard E.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
P
Pasupuleti, Nagarekha
- You have access5-Benzylglycinyl-Amiloride Kills Proliferating and Nonproliferating Malignant Glioma Cells through Caspase-Independent Necroptosis Mediated by Apoptosis-Inducing FactorNagarekha Pasupuleti, Leonardo Leon, Kermit L. Carraway and Fredric GorinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 600-615; DOI: https://doi.org/10.1124/jpet.112.200519
Peng, Jing-Hua
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Pilcher, Gary
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Pitis, Philip M.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Poli, Sonia
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Polson, Craig
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Price, Tulin O.
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
R
Rangwala, Huzaifa
- You have accessStructure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1Ruud P. M. Dings, Nigam Kumar, Michelle C. Miller, Melissa Loren, Huzaifa Rangwala, Thomas R. Hoye and Kevin H. MayoJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 589-599; DOI: https://doi.org/10.1124/jpet.112.199646
Raybon, Joseph J.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Rhyne, Paul W.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Rice, Kenner C.
- You have accessDiscriminative Stimulus Effects of the GABAB Receptor-Positive Modulator rac-BHFF: Comparison with GABAB Receptor Agonists and Drugs of AbuseWouter Koek, Kejun Cheng and Kenner C. RiceJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 553-560; DOI: https://doi.org/10.1124/jpet.112.202226
Rodrigues, A. David
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Rominger, David H.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Rouillier, Mélanie
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Royer-Urios, Isabelle
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
S
Salt, Thomas E.
- You have accessADX71743, a Potent and Selective Negative Allosteric Modulator of Metabotropic Glutamate Receptor 7: In Vitro and In Vivo CharacterizationMikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel, Sonia Poli, Stuart A. Neale, Thomas E. Salt and Robert LütjensJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 624-636; DOI: https://doi.org/10.1124/jpet.112.200915
Sanderson, Thomas
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Sankaranarayanan, Sethu
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Selvam, Sabariya
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Shah, Gul N.
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Sheibani, Nader
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Shen, Hong
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Shin, Eui S.
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Shukla, Vidyanand G.
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Simutis, Frank
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Slemmon, Randy
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Sorenson, Christine M.
- You have accessPharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and ApoptosisGul N. Shah, Tulin O. Price, William A. Banks, Yoichi Morofuji, Andrej Kovac, Nuran Ercal, Christine M. Sorenson, Eui S. Shin and Nader SheibaniJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 637-645; DOI: https://doi.org/10.1124/jpet.112.201400
Southern, Craig
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Starrett, John E.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Subramanian, Kumara V.
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Sukrutharaj, Sunil
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Sverdlov, Oleksandr
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
T
Taylor, Debra L.
- You have accessHigh-Throughput Identification and Characterization of Novel, Species-selective GPR35 AgonistsZaynab Neetoo-Isseljee, Amanda E. MacKenzie, Craig Southern, Jeff Jerman, Edward G. McIver, Nicholas Harries, Debra L. Taylor and Graeme MilliganJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 568-578; DOI: https://doi.org/10.1124/jpet.112.201798
Thakur, Ganesh A.
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Thorburn, Andrew
- You have accessAutophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy?Molly L. Bristol, Sean M. Emery, Paola Maycotte, Andrew Thorburn, Shweta Chakradeo and David A. GewirtzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 544-552; DOI: https://doi.org/10.1124/jpet.112.199802
Tong, Gary
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Toyn, Jeremy H.
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
V
Vaidhyanathan, Shruthi
- You have accessMechanisms Limiting Distribution of the Threonine-Protein Kinase B-RaFV600E Inhibitor Dabrafenib to the Brain: Implications for the Treatment of Melanoma Brain MetastasesRajendar K. Mittapalli, Shruthi Vaidhyanathan, Arkadiusz Z. Dudek and William F. ElmquistJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 655-664; DOI: https://doi.org/10.1124/jpet.112.201475
Vemuri, V. Kiran
- You have accessCannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist AntagonistsBrian D. Kangas, Marcus S. Delatte, V. Kiran Vemuri, Ganesh A. Thakur, Spyridon P. Nikas, Kumara V. Subramanian, Vidyanand G. Shukla, Alexandros Makriyannis and Jack BergmanJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 561-567; DOI: https://doi.org/10.1124/jpet.112.201962
Violin, Jonathan D.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
W
Wang, Jun-Sheng
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Wang, Xinwen
- You have accessCarboxylesterase 1 as a Determinant of Clopidogrel Metabolism and ActivationHao-Jie Zhu, Xinwen Wang, Brian E. Gawronski, Bryan J. Brinda, Dominick J. Angiolillo and John S. MarkowitzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 665-672; DOI: https://doi.org/10.1124/jpet.112.201640
White, Randy
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
X
Xu, Li-Li
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Xu, Lin
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Y
Yaden, Benjamin
- You have accessAn Engineered Human Follistatin Variant: Insights into the Pharmacokinetic and Pharmocodynamic Relationships of a Novel Molecule with Broad Therapeutic PotentialAmita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, Bryan E. Jones and Johnny E. CroyJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 616-623; DOI: https://doi.org/10.1124/jpet.112.201491
Yamashita, Dennis S.
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Yang, Zheng
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Yuan, Catherine
- You have accessA G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with MorphineScott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiao-Tao Chen, Philip M. Pitis, Dimitar Gotchev, Catherine Yuan, Michael Koblish, Michael W. Lark and Jonathan D. ViolinJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 708-717; DOI: https://doi.org/10.1124/jpet.112.201616
Z
Zaczek, Robert
- You have accessPharmacodynamics of Selective Inhibition of γ-Secretase by AvagacestatCharles F. Albright, Randy C. Dockens, Jere E. Meredith, Richard E. Olson, Randy Slemmon, Kimberley A. Lentz, Jun-Sheng Wang, R. Rex Denton, Gary Pilcher, Paul W. Rhyne, Joseph J. Raybon, Donna M. Barten, Catherine Burton, Jeremy H. Toyn, Sethu Sankaranarayanan, Craig Polson, Valerie Guss, Randy White, Frank Simutis, Thomas Sanderson, Kevin W. Gillman, John E. Starrett, Joanne Bronson, Oleksandr Sverdlov, Shu-Pang Huang, Lorna Castaneda, Howard Feldman, Vlad Coric, Robert Zaczek, John E. Macor, John Houston, Robert M. Berman and Gary TongJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 686-695; DOI: https://doi.org/10.1124/jpet.112.199356
Zhang, Renjie
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Zhao, Weiping
- You have accessCynomolgus Monkey as a Potential Model to Assess Drug Interactions Involving Hepatic Organic Anion Transporting Polypeptides: In Vitro, In Vivo, and In Vitro-to-In Vivo ExtrapolationHong Shen, Zheng Yang, Gabe Mintier, Yong-Hae Han, Cliff Chen, Praveen Balimane, Mohammed Jemal, Weiping Zhao, Renjie Zhang, Sanjith Kallipatti, Sabariya Selvam, Sunil Sukrutharaj, Prasad Krishnamurthy, Punit Marathe and A. David RodriguesJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 673-685; DOI: https://doi.org/10.1124/jpet.112.200691
Zhao, Yu
- You have accessPuerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut Leakage, Kupffer Cell Activation, and Endotoxin Receptors ExpressionJing-Hua Peng, Tuan Cui, Fu Huang, Liang Chen, Yu Zhao, Lin Xu, Li-Li Xu, Qin Feng and Yi-Yang HuJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 646-654; DOI: https://doi.org/10.1124/jpet.112.201137
Zhu, Hao-Jie
- You have accessCarboxylesterase 1 as a Determinant of Clopidogrel Metabolism and ActivationHao-Jie Zhu, Xinwen Wang, Brian E. Gawronski, Bryan J. Brinda, Dominick J. Angiolillo and John S. MarkowitzJournal of Pharmacology and Experimental Therapeutics March 2013, 344 (3) 665-672; DOI: https://doi.org/10.1124/jpet.112.201640
In this issue

Advertisement