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Research ArticleToxicology

Identification of Human Butyrylcholinesterase Organophosphate-Resistant Variants through a Novel Mammalian Enzyme Functional Screen

Jun Zhang, Sigeng Chen, Erik C. Ralph, Mary Dwyer and John R. Cashman
Journal of Pharmacology and Experimental Therapeutics December 2012, 343 (3) 673-682; DOI: https://doi.org/10.1124/jpet.112.198499

Article Information

vol. 343 no. 3 673-682
DOI 
https://doi.org/10.1124/jpet.112.198499
PubMed 
22956723
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 24, 2012
  • Accepted September 5, 2012
  • Published online November 14, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jun Zhang,
  2. Sigeng Chen,
  3. Erik C. Ralph,
  4. Mary Dwyer, and
  5. John R. Cashman
  1. Human BioMolecular Research Institute, San Diego, California
  1. Address correspondence to:
    John R. Cashman, Human BioMolecular Research Institute, 5310 Eastgate Mall, San Diego, CA 92121. E-mail: jcashman{at}hbri.org
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Research ArticleToxicology

Molecular Evolution of Human BChE OP-Resistant Variants

Jun Zhang, Sigeng Chen, Erik C. Ralph, Mary Dwyer and John R. Cashman
Journal of Pharmacology and Experimental Therapeutics December 1, 2012, 343 (3) 673-682; DOI: https://doi.org/10.1124/jpet.112.198499
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