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Research ArticleMetabolism, Transport, and Pharmacogenomics

Differential Effects of Nicotine Treatment and Ethanol Self-Administration on CYP2A6, CYP2B6 and Nicotine Pharmacokinetics in African Green Monkeys

C. S. Ferguson, S. Miksys, R. M. Palmour and R. F. Tyndale
Journal of Pharmacology and Experimental Therapeutics December 2012, 343 (3) 628-637; DOI: https://doi.org/10.1124/jpet.112.198564
C. S. Ferguson
Centre for Addiction and Mental Health and Departments of Psychiatry, Pharmacology, and Toxicology, University of Toronto, Toronto, Canada (C.S.F., S.M., R.F.T.); and Department of Psychiatry and Human Genetics, McGill University, Montreal, Canada (R.M.P.)
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S. Miksys
Centre for Addiction and Mental Health and Departments of Psychiatry, Pharmacology, and Toxicology, University of Toronto, Toronto, Canada (C.S.F., S.M., R.F.T.); and Department of Psychiatry and Human Genetics, McGill University, Montreal, Canada (R.M.P.)
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R. M. Palmour
Centre for Addiction and Mental Health and Departments of Psychiatry, Pharmacology, and Toxicology, University of Toronto, Toronto, Canada (C.S.F., S.M., R.F.T.); and Department of Psychiatry and Human Genetics, McGill University, Montreal, Canada (R.M.P.)
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R. F. Tyndale
Centre for Addiction and Mental Health and Departments of Psychiatry, Pharmacology, and Toxicology, University of Toronto, Toronto, Canada (C.S.F., S.M., R.F.T.); and Department of Psychiatry and Human Genetics, McGill University, Montreal, Canada (R.M.P.)
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Article Information

vol. 343 no. 3 628-637
DOI 
https://doi.org/10.1124/jpet.112.198564
PubMed 
22935730

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 18, 2012
  • Accepted August 29, 2012
  • Published online November 14, 2012.

Article Versions

  • Earlier version (August 30, 2012 - 11:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. C. S. Ferguson,
  2. S. Miksys,
  3. R. M. Palmour, and
  4. R. F. Tyndale
  1. Centre for Addiction and Mental Health and Departments of Psychiatry, Pharmacology, and Toxicology, University of Toronto, Toronto, Canada (C.S.F., S.M., R.F.T.); and Department of Psychiatry and Human Genetics, McGill University, Montreal, Canada (R.M.P.)
  1. Address correspondence to:
    Dr. Rachel F. Tyndale, Department of Pharmacology and Toxicology, University of Toronto, Rm 4326, 1 King's College Circle, Toronto ON, Canada M5S 1A8. E-mail: r.tyndale{at}utoronto.ca
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Journal of Pharmacology and Experimental Therapeutics: 343 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 343, Issue 3
1 Dec 2012
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Research ArticleMetabolism, Transport, and Pharmacogenomics

Nicotine and EtOH Affect CYP2A6, CYP2B6, and/or Nicotine PK

C. S. Ferguson, S. Miksys, R. M. Palmour and R. F. Tyndale
Journal of Pharmacology and Experimental Therapeutics December 1, 2012, 343 (3) 628-637; DOI: https://doi.org/10.1124/jpet.112.198564

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Nicotine and EtOH Affect CYP2A6, CYP2B6, and/or Nicotine PK

C. S. Ferguson, S. Miksys, R. M. Palmour and R. F. Tyndale
Journal of Pharmacology and Experimental Therapeutics December 1, 2012, 343 (3) 628-637; DOI: https://doi.org/10.1124/jpet.112.198564
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