Journal of Pharmacology and Experimental Therapeutics: 342 (3)

September 01, 2012; Volume 342,Issue 3

Highlighted Papers

You have access
Inverse Relationship between In Vitro Cannabinoid Efficacy and Decreased Sensitivity after Multiple Days of Dosing
Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 597;
You have access
Impact of Glucocorticosteroids and β₂-Adrenoceptor Agonists on Airway Smooth Muscle
Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 597;
You have access
Vidofludimus Improves Colitis in Rats by a Dual Mode of Action
Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 597;
You have access
Antinociceptive Effects of Nicotinic Partial Agonists in Acute and Tonic Pain Models
Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 597;

JPET Miniseries: Mitochondria

You have access
Mitochondrial Function and Dysfunction: An Update
Robert E. Davis and Michael Williams

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 598-607; DOI: https://doi.org/10.1124/jpet.112.192104
You have access
Oxidative Shielding or Oxidative Stress?
Robert K. Naviaux

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 608-618; DOI: https://doi.org/10.1124/jpet.112.192120
You have access
Mitochondrial Dysfunction in Neurodegenerative Diseases
Ashu Johri and M. Flint Beal

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 619-630; DOI: https://doi.org/10.1124/jpet.112.192138
You have access
Transgenic Mouse Models Resistant to Diet-Induced Metabolic Disease: Is Energy Balance the Key?
Laura A. A. Gilliam and P. Darrell Neufer

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 631-636; DOI: https://doi.org/10.1124/jpet.112.192146
You have access
Warburg Revisited: Regulation of Mitochondrial Metabolism by Voltage-Dependent Anion Channels in Cancer Cells
Eduardo N. Maldonado and John J. Lemasters

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 637-641; DOI: https://doi.org/10.1124/jpet.112.192153

Behavioral Pharmacology

You have access
The Serotonin 2C Receptor Antagonist SB 242084 Exhibits Abuse-Related Effects Typical of Stimulants in Squirrel Monkeys
Daniel F. Manvich, Heather L. Kimmel, Debra A. Cooper and Leonard L. Howell

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 761-769; DOI: https://doi.org/10.1124/jpet.112.195156
You have access
δ-Opioid Mechanisms for ADL5747 and ADL5859 Effects in Mice: Analgesia, Locomotion, and Receptor Internalization
Chihiro Nozaki, Bertrand Le Bourdonnec, David Reiss, Rolf T. Windh, Patrick J. Little, Roland E. Dolle, Brigitte L. Kieffer and Claire Gavériaux-Ruff

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 799-807; DOI: https://doi.org/10.1124/jpet.111.188987
You have access
Apparent Inverse Relationship between Cannabinoid Agonist Efficacy and Tolerance/Cross-Tolerance Produced by Δ⁹-Tetrahydrocannabinol Treatment in Rhesus Monkeys
Lenka Hruba, Brett C. Ginsburg and Lance R. McMahon

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 843-849; DOI: https://doi.org/10.1124/jpet.112.196444

Cardiovascular

You have access
Activation of AMP-Activated Protein Kinase Inhibits the Proliferation of Human Endothelial Cells
Kelly J. Peyton, Xiao-ming Liu, Yajie Yu, Benjamin Yates and William Durante

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 827-834; DOI: https://doi.org/10.1124/jpet.112.194712

Cellular and Molecular

You have access
Morphine Withdrawal Activates Hypothalamic-Pituitary-Adrenal Axis and Heat Shock Protein 27 in the Left Ventricle: The Role of Extracellular Signal-Regulated Kinase
E. Martínez-Laorden, M. A. Hurle, M. V. Milanés, M. L. Laorden and P. Almela

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 665-675; DOI: https://doi.org/10.1124/jpet.112.193581

Drug Discovery and Translational Medicine

You have access
Durable Pharmacological Responses from the Peptide ShK-186, a Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease
Eric J. Tarcha, Victor Chi, Ernesto J. Muñoz-Elías, David Bailey, Luz M. Londono, Sanjeev K. Upadhyay, Kayla Norton, Amy Banks, Indra Tjong, Hai Nguyen, Xueyou Hu, Greg W. Ruppert, Scott E. Boley, Richard Slauter, James Sams, Brian Knapp, Dustin Kentala, Zachary Hansen, Michael W. Pennington, Christine Beeton, K. George Chandy and Shawn P. Iadonato

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 642-653; DOI: https://doi.org/10.1124/jpet.112.191890
You have access
An Ex Vivo Perfusion System Emulating In Vivo Conditions in Noncirrhotic and Cirrhotic Human Liver
Thomas Schreiter, Guido Marquitan, Malin Darnell, Jan-Peter Sowa, Martina Bröcker-Preuss, Tommy B. Andersson, Hideo A. Baba, Marcus Furch, Gavin E. Arteel, Zoltan Mathé, Jürgen Treckmann, Guido Gerken, Robert K. Gieseler and Ali Canbay

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 730-741; DOI: https://doi.org/10.1124/jpet.112.194167
You have access
Pharmacokinetic/Pharmacodynamic Model of the Testosterone Effects of Triptorelin Administered in Sustained Release Formulations in Patients with Prostate Cancer
Elba Romero, Nieves Vélez de Mendizabal, Josep-María Cendrós, Concepción Peraire, Emma Bascompta, Rosendo Obach and Iñaki F. Trocóniz

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 788-798; DOI: https://doi.org/10.1124/jpet.112.195560
You have access
Vaccination with Platelet-Derived Growth Factor B Kinoids Inhibits CCl₄-Induced Hepatic Fibrosis in Mice
Zhi-Ming Hao, Xiao-Bao Fan, Shuang Li, Yi-Fei Lv, Hou-Qiang Su, Hui-Ping Jiang and Hong-Hong Li

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 835-842; DOI: https://doi.org/10.1124/jpet.112.194357

Gastrointestinal, Hepatic, Pulmonary, and Renal

You have access
Production and Actions of the Anandamide Metabolite Prostamide E2 in the Renal Medulla
Joseph K. Ritter, Cao Li, Min Xia, Justin L. Poklis, Aron H. Lichtman, Rehab A. Abdullah, William L. Dewey and Pin-Lan Li

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 770-779; DOI: https://doi.org/10.1124/jpet.112.196451

Inflammation, Immunopharmacology, and Asthma

You have access
Nodakenin Suppresses Lipopolysaccharide-Induced Inflammatory Responses in Macrophage Cells by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 and Nuclear Factor-κB Pathways and Protects Mice from Lethal Endotoxin Shock
Hong-Kun Rim, Woong Cho, Sang Hyun Sung and Kyung-Tae Lee

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 654-664; DOI: https://doi.org/10.1124/jpet.112.194613
You have access
Glucocorticosteroids and β₂-Adrenoceptor Agonists Synergize to Inhibit Airway Smooth Muscle Remodeling
Bart G. J. Dekkers, Adnan Pehlić, Raissa Mariani, I. Sophie T. Bos, Herman Meurs and Johan Zaagsma

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 780-787; DOI: https://doi.org/10.1124/jpet.112.195867
You have access
Soluble Glucan Is Internalized and Trafficked to the Golgi Apparatus in Macrophages via a Clathrin-Mediated, Lipid Raft-Regulated Mechanism
Tammy R. Ozment, Matthew P. Goldman, John H. Kalbfleisch and David L. Williams

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 808-815; DOI: https://doi.org/10.1124/jpet.112.196329
You have access
15-Deoxy-Δ^12,14-Prostaglandin J₂-Glycerol, a Putative Metabolite of 2-Arachidonyl Glycerol and a Peroxisome Proliferator-Activated Receptor γ Ligand, Modulates Nuclear Factor of Activated T Cells
Priyadarshini Raman, Barbara L. F. Kaplan and Norbert E. Kaminski

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 816-826; DOI: https://doi.org/10.1124/jpet.112.193003
You have access
Vidofludimus Inhibits Colonic Interleukin-17 and Improves Hapten-Induced Colitis in Rats by a Unique Dual Mode of Action
Leo R. Fitzpatrick, Jeffrey S. Small, Robert Doblhofer and Aldo Ammendola

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 850-860; DOI: https://doi.org/10.1124/jpet.112.192203

Metabolism, Transport, and Pharmacogenomics

You have access
Hormonal and Chemical Regulation of Paraoxonases in Mice
Xingguo Cheng and Curtis D. Klaassen

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 688-695; DOI: https://doi.org/10.1124/jpet.112.194803
You have access
Intestinal Transport of Aminopterin Enantiomers in Dogs and Humans with Psoriasis Is Stereoselective: Evidence for a Mechanism Involving the Proton-Coupled Folate Transporter
Alan Menter, Breck Thrash, Christina Cherian, Larry H. Matherly, Lei Wang, Aleem Gangjee, Joel R. Morgan, Dean Y. Maeda, Aaron D. Schuler, Stuart J. Kahn and John A. Zebala

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 696-708; DOI: https://doi.org/10.1124/jpet.112.195479
You have access
Bioenergetic Effects of Mitochondrial-Targeted Coenzyme Q Analogs in Endothelial Cells
Brian D. Fink, Judith A. Herlein, Mark A. Yorek, Amanda M. Fenner, Robert J. Kerns and William I. Sivitz

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 709-719; DOI: https://doi.org/10.1124/jpet.112.195586
You have access
Quantification of Hepatic UDP Glucuronosyltransferase 1A Splice Variant Expression and Correlation of UDP Glucuronosyltransferase 1A1 Variant Expression with Glucuronidation Activity
Nathan R. Jones, Dongxiao Sun, Willard M. Freeman and Philip Lazarus

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 720-729; DOI: https://doi.org/10.1124/jpet.112.192658
You have access
Phenanthrene Metabolism in Smokers: Use of a Two-Step Diagnostic Plot Approach to Identify Subjects with Extensive Metabolic Activation
Jing Wang, Yan Zhong, Steven G. Carmella, J. Bradley Hochalter, Diane Rauch, Andrew Oliver, Joni Jensen, Dorothy K. Hatsukami, Pramod Upadhyaya, Stephen S. Hecht and Cheryl L. Zimmerman

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 750-760; DOI: https://doi.org/10.1124/jpet.112.194118

Neuropharmacology

You have access
The Antinociceptive Effects of Nicotinic Partial Agonists Varenicline and Sazetidine-A in Murine Acute and Tonic Pain Models
Shakir D. AlSharari, F. Ivy Carroll, J. Michael McIntosh and M. Imad Damaj

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 742-749; DOI: https://doi.org/10.1124/jpet.112.194506

Toxicology

You have access
Differences in Early Acetaminophen Hepatotoxicity between Obese ob/ob and db/db Mice
Jacinthe Aubert, Karima Begriche, Matthieu Delannoy, Isabelle Morel, Julie Pajaud, Catherine Ribault, Sylvie Lepage, Mitchell R. McGill, Catherine Lucas-Clerc, Bruno Turlin, Marie-Anne Robin, Hartmut Jaeschke and Bernard Fromenty

Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 676-687; DOI: https://doi.org/10.1124/jpet.112.193813

Notice of Withdrawal

You have access
Notice of Withdrawal
Journal of Pharmacology and Experimental Therapeutics September 2012, 342 (3) 861;

Main menu

User menu

Search

Table of Contents

Highlighted Papers

JPET Miniseries: Mitochondria

Behavioral Pharmacology

Cardiovascular

Cellular and Molecular

Drug Discovery and Translational Medicine

Gastrointestinal, Hepatic, Pulmonary, and Renal

Inflammation, Immunopharmacology, and Asthma

Metabolism, Transport, and Pharmacogenomics

Neuropharmacology

Toxicology

Notice of Withdrawal

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals