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Research ArticleEndocrine and Diabetes

KGA-2727, a Novel Selective Inhibitor of a High-Affinity Sodium Glucose Cotransporter (SGLT1), Exhibits Antidiabetic Efficacy in Rodent Models

Toshihide Shibazaki, Masaki Tomae, Yukiko Ishikawa-Takemura, Nobuhiko Fushimi, Fumiaki Itoh, Mitsuhiko Yamada and Masayuki Isaji
Journal of Pharmacology and Experimental Therapeutics August 2012, 342 (2) 288-296; DOI: https://doi.org/10.1124/jpet.112.193045
Toshihide Shibazaki
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Masaki Tomae
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Yukiko Ishikawa-Takemura
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Nobuhiko Fushimi
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Fumiaki Itoh
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Mitsuhiko Yamada
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Masayuki Isaji
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Article Information

vol. 342 no. 2 288-296
DOI 
https://doi.org/10.1124/jpet.112.193045
PubMed 
22537769

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 10, 2012
  • Accepted April 23, 2012
  • Published online July 16, 2012.

Article Versions

  • Earlier version (April 26, 2012 - 11:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Toshihide Shibazaki,
  2. Masaki Tomae,
  3. Yukiko Ishikawa-Takemura,
  4. Nobuhiko Fushimi,
  5. Fumiaki Itoh,
  6. Mitsuhiko Yamada and
  7. Masayuki Isaji
  1. Central Research Laboratory, Kissei Pharmaceutical Co., Ltd., Azumino, Japan (T.S., M.T., Y.I.-T., N.F., F.I., M.I.); and Department of Molecular Pharmacology, Shinshu University School of Medicine, Matsumoto, Japan (M.Y.)
  1. Address correspondence to:
    Masayuki Isaji, Central Research Laboratory, Kissei Pharmaceutical Co., Ltd., 4365-1, Hotaka, Azumino, Nagano 399-8304, Japan. E-mail: masayuki_isaji{at}pharm.kissei.co.jp
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Journal of Pharmacology and Experimental Therapeutics: 342 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 342, Issue 2
1 Aug 2012
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Research ArticleEndocrine and Diabetes

SGLT1 Selective Inhibitor Has Antidiabetic Efficacy

Toshihide Shibazaki, Masaki Tomae, Yukiko Ishikawa-Takemura, Nobuhiko Fushimi, Fumiaki Itoh, Mitsuhiko Yamada and Masayuki Isaji
Journal of Pharmacology and Experimental Therapeutics August 1, 2012, 342 (2) 288-296; DOI: https://doi.org/10.1124/jpet.112.193045

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Research ArticleEndocrine and Diabetes

SGLT1 Selective Inhibitor Has Antidiabetic Efficacy

Toshihide Shibazaki, Masaki Tomae, Yukiko Ishikawa-Takemura, Nobuhiko Fushimi, Fumiaki Itoh, Mitsuhiko Yamada and Masayuki Isaji
Journal of Pharmacology and Experimental Therapeutics August 1, 2012, 342 (2) 288-296; DOI: https://doi.org/10.1124/jpet.112.193045
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