Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

July 01, 2012; Volume 342,Issue 1

Highlighted Papers

  • You have access
    Lyn Activation and Restoring Glucose Tolerance
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 1;
  • You have access
    Lyn Kinase Activator MLR-1023 Potentiates Insulin and Improves Glucose Homeostasis
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 1;
  • You have access
    Regulation of Vemurafenib Exposure in the Brain by ABC Transporters
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 1;
  • You have access
    Attenuation of Chemotherapy-Induced Peripheral Neuropathy by Etodolac
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 1;

Perspectives in Pharmacology

  • You have access
    Revisiting the Isobole and Related Quantitative Methods for Assessing Drug Synergism
    Ronald J. Tallarida
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 2-8; DOI: https://doi.org/10.1124/jpet.112.193474
  • You have access
    Cigarette Smoking, Coffee Drinking, and Ingestion of Charcoal-Broiled Beef as Potential Modifiers of Drug Therapy and Confounders of Clinical Trials
    A. H. Conney and M. M. Reidenberg
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 9-14; DOI: https://doi.org/10.1124/jpet.112.193193

Behavioral Pharmacology

  • You have access
    Effects of Alterations in Cannabinoid Signaling, Alone and in Combination with Morphine, on Pain-Elicited and Pain-Suppressed Behavior in Mice
    Laurence L. Miller, Mitchell J. Picker, Michael D. Umberger, Karl T. Schmidt and Linda A. Dykstra
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 177-187; DOI: https://doi.org/10.1124/jpet.112.191478
  • You have access
    Cocaine Dose and Self-Administration History, but Not Initial Cocaine Locomotor Responsiveness, Affects Sensitization to the Motivational Effects of Cocaine in Rats
    Bruce H. Mandt, Emily Gomez, Nickie L. Johnston, Nancy R. Zahniser and Richard M. Allen
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 214-221; DOI: https://doi.org/10.1124/jpet.112.194092

Cardiovascular

  • You have access
    Polyethylene Glycol-Modified Pigment Epithelial-Derived Factor: New Prospects for Treatment of Retinal Neovascularization
    Yu-Jing Bai, Lv-Zhen Huang, Xiao-Lei Xu, Wei Du, Ai-Yi Zhou, Wen-Zhen Yu and Xiao-Xin Li
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 131-139; DOI: https://doi.org/10.1124/jpet.112.192575

Chemotherapy, Antibiotics, and Gene Therapy

  • You have access
    Combining Doublecortin-Like Kinase Silencing and Vinca Alkaloids Results in a Synergistic Apoptotic Effect in Neuroblastoma Cells
    Carla S. Verissimo, Sou Cheng, Jordi C. Puigvert, Yu Qin, Anne Vroon, Judith van Deutekom, Leo S. Price, Erik H. J. Danen, Bob van de Water, Carlos P. Fitzsimons and Erno Vreugdenhil
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 119-130; DOI: https://doi.org/10.1124/jpet.111.188813

Drug Discovery and Translational Medicine

  • You have access
    The β2-Adrenoceptor Agonist Formoterol Stimulates Mitochondrial Biogenesis
    Lauren P. Wills, Richard E. Trager, Gyda C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Craig C. Beeson and Rick G. Schnellmann
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 106-118; DOI: https://doi.org/10.1124/jpet.112.191528
  • You have access
    The Novel Reversible Fatty Acid Amide Hydrolase Inhibitor ST4070 Increases Endocannabinoid Brain Levels and Counteracts Neuropathic Pain in Different Animal Models
    Antonio Caprioli, Roberto Coccurello, Cinzia Rapino, Stefano Di Serio, Monia Di Tommaso, Mario Vertechy, Valentina Vacca, Natalia Battista, Flaminia Pavone, Mauro Maccarrone and Franco Borsini
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 188-195; DOI: https://doi.org/10.1124/jpet.111.191403
  • You have access
    Arginine Attenuates Methylglyoxal- and High Glucose-Induced Endothelial Dysfunction and Oxidative Stress by an Endothelial Nitric-Oxide Synthase-Independent Mechanism
    Indu Dhar, Arti Dhar, Lingyun Wu and Kaushik Desai
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 196-204; DOI: https://doi.org/10.1124/jpet.112.192112
  • You have access
    Repeated Administration of a Mutant Cocaine Esterase: Effects on Plasma Cocaine Levels, Cocaine-Induced Cardiovascular Activity, and Immune Responses in Rhesus Monkeys
    Gregory T. Collins, Remy L. Brim, Kathleen R. Noon, Diwahar Narasimhan, Nicholas W. Lukacs, Roger K. Sunahara, James H. Woods and Mei-Chuan Ko
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 205-213; DOI: https://doi.org/10.1124/jpet.112.194639

Endocrine and Diabetes

  • You have access
    MLR-1023 Is a Potent and Selective Allosteric Activator of Lyn Kinase In Vitro That Improves Glucose Tolerance In Vivo
    Michael S. Saporito, Alexander R. Ochman, Christopher A. Lipinski, Jeffrey A. Handler and Andrew G. Reaume
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 15-22; DOI: https://doi.org/10.1124/jpet.112.192096
  • You have access
    The Lyn Kinase Activator MLR-1023 Is a Novel Insulin Receptor Potentiator that Elicits a Rapid-Onset and Durable Improvement in Glucose Homeostasis in Animal Models of Type 2 Diabetes
    Alexander R. Ochman, Christopher A. Lipinski, Jeffrey A. Handler, Andrew G. Reaume and Michael S. Saporito
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 23-32; DOI: https://doi.org/10.1124/jpet.112.192187
  • You have access
    The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Attenuates Inflammation and Accelerates Epithelialization in Wounds of Diabetic ob/ob Mice
    Christoph Schürmann, Andreas Linke, Kerstin Engelmann-Pilger, Cornelia Steinmetz, Michael Mark, Josef Pfeilschifter, Thomas Klein and Stefan Frank
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 71-80; DOI: https://doi.org/10.1124/jpet.111.191098

Gastrointestinal, Hepatic, Pulmonary, and Renal

  • You have access
    Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1 Plays a Role in the Impairing Effects of Cyclooxygenase Inhibitors on Gastric Ulcer Healing
    Rocchina Colucci, Luca Antonioli, Nunzia Bernardini, Chiara Ippolito, Cristina Segnani, Oriana Awwad, Marco Tuccori, Corrado Blandizzi, Carmelo Scarpignato and Matteo Fornai
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 140-149; DOI: https://doi.org/10.1124/jpet.111.190116
  • You have access
    Effects of Ritobegron (KUC-7483), a Novel Selective β3-Adrenoceptor Agonist, on Bladder Function in Cynomolgus Monkey
    Itaru Maruyama, Satoshi Tatemichi, Yoshiaki Goi, Kazuyasu Maruyama, Yuji Hoyano, Yoshinobu Yamazaki and Hiroshi Kusama
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 163-168; DOI: https://doi.org/10.1124/jpet.112.191783

Inflammation, Immunopharmacology, and Asthma

  • You have access
    Carnosol and Carnosic Acids from Salvia officinalis Inhibit Microsomal Prostaglandin E2 Synthase-1
    Julia Bauer, Susanne Kuehnl, Judith M. Rollinger, Olga Scherer, Hinnak Northoff, Hermann Stuppner, Oliver Werz and Andreas Koeberle
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 169-176; DOI: https://doi.org/10.1124/jpet.112.193847

Metabolism, Transport, and Pharmacogenomics

  • You have access
    Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on the Brain Distribution of a Novel BRAF Inhibitor: Vemurafenib (PLX4032)
    Rajendar K. Mittapalli, Shruthi Vaidhyanathan, Ramola Sane and William F. Elmquist
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 33-40; DOI: https://doi.org/10.1124/jpet.112.192195

Neuropharmacology

  • You have access
    Morphine Activates the E Twenty Six-Like Transcription Factor-1/Serum Response Factor Pathway via Extracellular Signal-Regulated Kinases 1/2 in F11 Cells Derived from Dorsal Root Ganglia Neurons
    Kathrin Rothe, Hans Jürgen Solinski, Ingrid Boekhoff, Thomas Gudermann and Andreas Breit
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 41-52; DOI: https://doi.org/10.1124/jpet.112.192757
  • You have access
    Etodolac, a Cyclooxygenase-2 Inhibitor, Attenuates Paclitaxel-Induced Peripheral Neuropathy in a Mouse Model of Mechanical Allodynia
    Sunao Ito, Koyuki Tajima, Masaki Nogawa, Naoki Inoue, Takashi Kyoi, Yosuke Takahashi, Takahiro Sasagawa, Akio Nakamura, Takashi Kotera, Makoto Ueda, Yasuhiro Yamashita and Kouji Banno
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 53-60; DOI: https://doi.org/10.1124/jpet.111.187401
  • You have access
    Positive Allosteric Modulators Differentially Affect Full versus Partial Agonist Activation of the Glycine Receptor
    Dean Kirson, Jelena Todorovic and S. John Mihic
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 61-70; DOI: https://doi.org/10.1124/jpet.112.191486
  • You have access
    Pharmacology of JNJ-37822681, a Specific and Fast-Dissociating D2 Antagonist for the Treatment of Schizophrenia
    Xavier Langlois, Anton Megens, Hilde Lavreysen, John Atack, Miroslav Cik, Paula te Riele, Luc Peeters, Ria Wouters, Jef Vermeire, Herman Hendrickx, Gregor Macdonald and Marcel De Bruyn
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 91-105; DOI: https://doi.org/10.1124/jpet.111.190702
  • You have access
    Pyroglutamyl Peptidase II Inhibition Enhances the Analeptic Effect of Thyrotropin-Releasing Hormone in the Rat Medial Septum
    Ivan Lazcano, Rosa Maria Uribe, Erick Martínez-Chávez, Miguel Angel Vargas, Magdalini Matziari, Patricia Joseph-Bravo and Jean-Louis Charli
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 222-231; DOI: https://doi.org/10.1124/jpet.112.192278

Toxicology

  • You have access
    Resveratrol Inhibits Paraquat-Induced Oxidative Stress and Fibrogenic Response by Activating the Nuclear Factor Erythroid 2-Related Factor 2 Pathway
    Xiaoqing He, Liping Wang, Grazyna Szklarz, Yongyi Bi and Qiang Ma
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 81-90; DOI: https://doi.org/10.1124/jpet.112.194142
  • You have access
    Unique O-Methoxyethyl Ribose-DNA Chimeric Oligonucleotide Induces an Atypical Melanoma Differentiation-Associated Gene 5-Dependent Induction of Type I Interferon Response
    Sebastien A. Burel, Todd Machemer, Frank L. Ragone, Hiroki Kato, Patrick Cauntay, Sarah Greenlee, Aneeza Salim, William A. Gaarde, Gene Hung, Raechel Peralta, Susan M. Freier and Scott P. Henry
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 150-162; DOI: https://doi.org/10.1124/jpet.112.193789

Erratum

  • You have access
    Correction to “Synergistic Interaction between the Two Mechanisms of Action of Tapentadol in Analgesia”
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 232;

Notice of Retraction

  • You have access
    Notice of Retraction
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 233;

Notice of Withdrawal

  • You have access
    Notice of Withdrawal
    Journal of Pharmacology and Experimental Therapeutics July 2012, 342 (1) 234;
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 342 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 342, Issue 1
1 Jul 2012
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Highlighted Papers
  • Perspectives in Pharmacology
  • Behavioral Pharmacology
  • Cardiovascular
  • Chemotherapy, Antibiotics, and Gene Therapy
  • Drug Discovery and Translational Medicine
  • Endocrine and Diabetes
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Inflammation, Immunopharmacology, and Asthma
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
  • Toxicology
  • Erratum
  • Notice of Retraction
  • Notice of Withdrawal
  • Most Cited
  • Most Read
Loading
  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics