Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn
Research ArticleNeuropharmacology

S32212, a Novel Serotonin Type 2C Receptor Inverse Agonist/α2-Adrenoceptor Antagonist and Potential Antidepressant: I. A Mechanistic Characterization

Mark J. Millan, Clotilde Mannoury la Cour, Benjamin Chanrion, Delphine S. Dupuis, Benjamin Di Cara, Valérie Audinot, Didier Cussac, Adrian Newman-Tancredi, Maud Kamal, Jean A. Boutin, Ralf Jockers, Philippe Marin, Joël Bockaert, Olivier Muller, Anne Dekeyne and Gilbert Lavielle
Journal of Pharmacology and Experimental Therapeutics March 2012, 340 (3) 750-764; DOI: https://doi.org/10.1124/jpet.111.187468
Mark J. Millan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Clotilde Mannoury la Cour
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Benjamin Chanrion
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Delphine S. Dupuis
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Benjamin Di Cara
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Valérie Audinot
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Didier Cussac
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adrian Newman-Tancredi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maud Kamal
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jean A. Boutin
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ralf Jockers
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Philippe Marin
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joël Bockaert
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Olivier Muller
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anne Dekeyne
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gilbert Lavielle
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 340 no. 3 750-764
DOI 
https://doi.org/10.1124/jpet.111.187468
PubMed 
22178752

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 30, 2011
  • Accepted November 29, 2011
  • Published online February 14, 2012.

Article Versions

  • Earlier version (December 16, 2011 - 08:49).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mark J. Millan,
  2. Clotilde Mannoury la Cour,
  3. Benjamin Chanrion,
  4. Delphine S. Dupuis,
  5. Benjamin Di Cara,
  6. Valérie Audinot,
  7. Didier Cussac,
  8. Adrian Newman-Tancredi,
  9. Maud Kamal,
  10. Jean A. Boutin,
  11. Ralf Jockers,
  12. Philippe Marin,
  13. Joël Bockaert,
  14. Olivier Muller,
  15. Anne Dekeyne and
  16. Gilbert Lavielle
  1. Departments of Psychopharmacology (M.J.M., C.M.l.C., B.C., D.S.D., B.D.C., D.C., A.N.-T., A.D.), Molecular and Cellular Pharmacology (V.A., J.A.B.), and Chemistry (O.M., G.L.), Institut de Recherches Servier, Centre de Recherches de Croissy, Croissy/Seine, Paris, France; Institut National de la Santé et de la Recherche Médicale U1016, Institut Cochin, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France (M.K., R.J.); and Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, Universités Montpellier I and II, Montpellier, France (B.C., P.M., J.B.)
  1. Address correspondence to:
    Dr. Mark J. Millan, Institut de Recherches Servier, Centre de Recherches de Croissy, Psychopharmacology Department, 125 Chemin de Ronde, 78290 Croissy/Seine, France. E-mail: mark.millan{at}fr.netgrs.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: December 2011 to May 2023

AbstractFullPdf
Dec 2011160039
Jan 201293071
Feb 20123111380
Mar 20122711837
Apr 2012109820
May 2012931528
Jun 2012521420
Jul 2012541620
Aug 201254513
Sep 2012541527
Oct 201235914
Nov 2012451416
Dec 2012261018
Jan 20133827
Feb 2013491010
Mar 2013371119
Apr 2013283317
May 2013333023
Jun 2013241010
Jul 201319148
Aug 2013774
Sep 201346179
Oct 201328166
Nov 2013182510
Dec 2013131513
Jan 201416259
Feb 2014151820
Mar 201412185
Apr 2014161112
May 2014956
Jun 2014131111
Jul 2014212214
Aug 201412104
Sep 201461014
Oct 201416107
Nov 201418194
Dec 2014161110
Jan 2015172018
Feb 20159205
Mar 201515269
Apr 20158197
May 2015142111
Jun 201510155
Jul 201561019
Aug 201512193
Sep 201521274
Oct 201512218
Nov 2015202010
Dec 20156145
Jan 201625168
Feb 2016142418
Mar 2016151317
Apr 2016252311
May 2016182411
Jun 2016201721
Jul 20169129
Aug 2016142518
Sep 2016154113
Oct 20162569
Nov 20165565
Dec 201644612
Jan 201716315
Feb 201715727
Mar 201727727
Apr 201715313
May 201713622
Jun 20173186
Jul 201712911
Aug 20171278
Sep 20174308
Oct 20176244
Nov 20173335
Dec 20173256
Jan 20184295
Feb 2018162615
Mar 201867821
Apr 201878422
May 201822418
Jun 20184324
Jul 20181144
Aug 20183192
Sep 20181265
Oct 20181100
Nov 20181337
Dec 20181620
Jan 201929117
Feb 201919112
Mar 201931414
Apr 201919211
May 20191216
Jun 20193608
Jul 20192203
Aug 20194007
Sep 20192721
Oct 20192212
Nov 20192504
Dec 20194213
Jan 20202947
Feb 20201002
Mar 20201433
Apr 20203322
May 20204922
Jun 2020741
Jul 20201500
Aug 20201434
Sep 20201811
Oct 20201211
Nov 20203165
Dec 20204215
Jan 20212327
Feb 20212163
Mar 20213010
Apr 20212520
May 202127119
Jun 20212811
Jul 20212033
Aug 20211942
Sep 20211954
Oct 20211621
Nov 20212654
Dec 20213029
Jan 20223225
Feb 20223231
Mar 20222845
Apr 20224327
May 20221832
Jun 20221920
Jul 20222631
Aug 20223527
Sep 20222145
Oct 202213210
Nov 20221821
Dec 20222212
Jan 20234734
Feb 20231333
Mar 20233213
Apr 20231422
May 20232434

PreviousNext
Back to top

In this issue

Journal of Pharmacology and Experimental Therapeutics: 340 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 340, Issue 3
1 Mar 2012
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Journal of Pharmacology and Experimental Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
S32212, a Novel Serotonin Type 2C Receptor Inverse Agonist/α2-Adrenoceptor Antagonist and Potential Antidepressant: I. A Mechanistic Characterization
(Your Name) has forwarded a page to you from Journal of Pharmacology and Experimental Therapeutics
(Your Name) thought you would be interested in this article in Journal of Pharmacology and Experimental Therapeutics.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleNeuropharmacology

5-HT2C Receptors, α2-Adrenoceptors, and Depression

Mark J. Millan, Clotilde Mannoury la Cour, Benjamin Chanrion, Delphine S. Dupuis, Benjamin Di Cara, Valérie Audinot, Didier Cussac, Adrian Newman-Tancredi, Maud Kamal, Jean A. Boutin, Ralf Jockers, Philippe Marin, Joël Bockaert, Olivier Muller, Anne Dekeyne and Gilbert Lavielle
Journal of Pharmacology and Experimental Therapeutics March 1, 2012, 340 (3) 750-764; DOI: https://doi.org/10.1124/jpet.111.187468

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleNeuropharmacology

5-HT2C Receptors, α2-Adrenoceptors, and Depression

Mark J. Millan, Clotilde Mannoury la Cour, Benjamin Chanrion, Delphine S. Dupuis, Benjamin Di Cara, Valérie Audinot, Didier Cussac, Adrian Newman-Tancredi, Maud Kamal, Jean A. Boutin, Ralf Jockers, Philippe Marin, Joël Bockaert, Olivier Muller, Anne Dekeyne and Gilbert Lavielle
Journal of Pharmacology and Experimental Therapeutics March 1, 2012, 340 (3) 750-764; DOI: https://doi.org/10.1124/jpet.111.187468
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Authorship Contributions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • VTA Muscarinic M5 Receptors and Effort-Choice Behavior
  • Substituted Tryptamine Activity at 5-HT Receptors and SERT
  • KRM-II-81 Analogs
Show more Neuropharmacology

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics