Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn
Research ArticleMetabolism, Transport, and Pharmacogenomics

An Insulin-Like Growth Factor 1 Receptor Inhibitor Induces CYP3A4 Expression through a Pregnane X Receptor-Independent, Noncanonical Constitutive Androstane Receptor-Related Mechanism

Linhao Li, Michael W. Sinz, Kurt Zimmermann and Hongbing Wang
Journal of Pharmacology and Experimental Therapeutics March 2012, 340 (3) 688-697; DOI: https://doi.org/10.1124/jpet.111.188854
Linhao Li
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael W. Sinz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kurt Zimmermann
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hongbing Wang
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 340 no. 3 688-697
DOI 
https://doi.org/10.1124/jpet.111.188854
PubMed 
22171088

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received October 7, 2011
  • Accepted December 6, 2011
  • Published online February 14, 2012.

Article Versions

  • Earlier version (December 9, 2011 - 07:04).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Linhao Li,
  2. Michael W. Sinz,
  3. Kurt Zimmermann and
  4. Hongbing Wang
  1. Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland (L.L., H.W.); and Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S., K.Z.)
  1. Address correspondence to:
    Dr. Hongbing Wang, Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD 21201. E-mail: hwang{at}rx.umaryland.edu
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: December 2011 to March 2021

AbstractFullPdf
Dec 2011181092
Jan 2012940110
Feb 201234123140
Mar 20122451432
Apr 20121261719
May 2012932429
Jun 201271819
Jul 201265618
Aug 201255514
Sep 201255810
Oct 2012501117
Nov 201231712
Dec 201217815
Jan 2013621932
Feb 201344870
Mar 201334923
Apr 201334914
May 201319516
Jun 2013111212
Jul 2013151110
Aug 2013121510
Sep 201325913
Oct 2013241111
Nov 20131476
Dec 2013171815
Jan 20141169
Feb 201411415
Mar 20141396
Apr 20141676
May 2014171012
Jun 20141088
Jul 2014201011
Aug 2014641
Sep 2014825
Oct 20141368
Nov 2014758
Dec 201412210
Jan 20151479
Feb 20151657
Mar 201510107
Apr 2015878
May 20159613
Jun 2015443
Jul 201510514
Aug 2015522
Sep 2015881
Oct 2015935
Nov 20151012
Dec 20151488
Jan 201633119
Feb 2016479
Mar 201613912
Apr 2016641
May 2016543
Jun 20162098
Jul 2016753
Aug 20161366
Sep 20161244
Oct 201672426
Nov 2016141110
Dec 20161133
Jan 2017172
Feb 20171192
Mar 20174116
Apr 20170101
May 20170114
Jun 2017162
Jul 20172110
Aug 2017178
Sep 201721420
Oct 20171157
Nov 20171153
Dec 20170124
Jan 20181192
Feb 201833024
Mar 201811211
Apr 201821611
May 20180117
Jun 20180913
Jul 201821610
Aug 2018144
Sep 2018065
Oct 2018284
Nov 2018037
Dec 20189010
Jan 2019810
Feb 2019411
Mar 20191603
Apr 20191020
May 2019453
Jun 2019709
Jul 20191001
Aug 20191221
Sep 20191314
Oct 2019700
Nov 20192202
Dec 20191923
Jan 2020930
Feb 20201201
Mar 20201412
Apr 2020610
May 2020531
Jun 20202300
Jul 20202252
Aug 2020133
Sep 2020551
Oct 2020771
Nov 2020713
Dec 2020901
Jan 20211152
Feb 202114105
Mar 2021700

PreviousNext
Back to top

In this issue

Journal of Pharmacology and Experimental Therapeutics: 340 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 340, Issue 3
1 Mar 2012
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Journal of Pharmacology and Experimental Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
An Insulin-Like Growth Factor 1 Receptor Inhibitor Induces CYP3A4 Expression through a Pregnane X Receptor-Independent, Noncanonical Constitutive Androstane Receptor-Related Mechanism
(Your Name) has forwarded a page to you from Journal of Pharmacology and Experimental Therapeutics
(Your Name) thought you would be interested in this article in Journal of Pharmacology and Experimental Therapeutics.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleMetabolism, Transport, and Pharmacogenomics

Nonclassical CAR-Dependent Induction of CYP3A4 Expression

Linhao Li, Michael W. Sinz, Kurt Zimmermann and Hongbing Wang
Journal of Pharmacology and Experimental Therapeutics March 1, 2012, 340 (3) 688-697; DOI: https://doi.org/10.1124/jpet.111.188854

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Research ArticleMetabolism, Transport, and Pharmacogenomics

Nonclassical CAR-Dependent Induction of CYP3A4 Expression

Linhao Li, Michael W. Sinz, Kurt Zimmermann and Hongbing Wang
Journal of Pharmacology and Experimental Therapeutics March 1, 2012, 340 (3) 688-697; DOI: https://doi.org/10.1124/jpet.111.188854
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Authorship Contributions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • HDL Mimetic 4F Modulates Aβ Distribution in Brain and Plasma
  • AOX1 Inhibition by Gefitinib, Erlotinib, and Metabolites
  • Catalytic Activity of CYP2C9 Variants
Show more Metabolism, Transport, and Pharmacogenomics

Similar Articles

  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics